Table 1
Demographic data of Essential Tremor and reference sample groups.
| DEMOGRAPHIC DATA | ET SAMPLE (N = 15) | NON-ET SAMPLE (N = 15) |
|---|---|---|
| Age (years ± SD) | 51.86 ± 17.17 | 46.13 ± 13.75 |
| Sex F(M) | 10(5) | 10(5) |
| Right-handed laterality (n) | 15 | 15 |
| Smokers (n) | 2 | 2 |
| Consumption of CNS acting drugs (n) | 0 | 0 |
| Evidence of neurologic disease other than essential tremor (n) | 0 | 0 |
| Adverse effects (n) | 3 | 1 |
| Mild | 3 | 1 |
| Moderate | 0 | 0 |
| Severe | 0 | 0 |
| Correctly guessed pill content (n) | 8 | 7 |
| Familiar history of essential tremor (n) | 7 | 0 |
| Age at ET diagnosis (years ± SD). | 50.8 ± 17.72 | NA |
| Time with disease (years ± SD). | 10.08 ± 7.27 | NA |
| History of favorable response to alcohol intake (n) | 4 | NA |
[i] n, number of subjects; SD, standard deviation; F, female; M, male; CNS, central nervous system; ET, essential tremor.
Figure 1
WHIGET tremor score for the ET and reference sample groups after placebo or propranolol intake. *p < 0.05 for the subjects administered propranolol.
Figure 2
Resting and active motor threshold for the ET and reference sample groups in the right and left hemispheres after placebo or propranolol intake. *p < 0.05 for the subjects given propranolol (rMT, resting motor threshold; aMT, active motor threshold).
Figure 3
MEPs amplitude and MEPs amplitude while in contraction for the ET and reference sample groups in the right and left hemispheres after placebo or propranolol intake. *p < 0.05 for the subjects given propranolol (MEP, motor evoked potential).
Figure 4
I/O curve in the right and left hemisphere of the ET and reference sample groups after placebo or propranolol intake. *p < 0.05 for the subjects given propranolol.
Figure 5
I/O area under the curve in the right and left hemisphere of the ET and reference sample groups after placebo or propranolol intake. *p < 0.05 for the subjects given propranolol.