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Correction: Can Plasma α-Synuclein Help Us to Differentiate Parkinson’s Disease from Essential Tremor? Cover

Correction: Can Plasma α-Synuclein Help Us to Differentiate Parkinson’s Disease from Essential Tremor?

Open Access
|Jun 2021

Full Article

Correction

In Table 1 of Albillos et al. [1] there is no Off-State N = 33 value of NMSS total score and of PDCRS total score.

Table 1

Comparison of participant’s characteristics.

NOVO-PD
N = 19
PD
N = 35
ET
N = 19
CONTROLS
N = 35
P-VALUE
ON-STATEOFF-STATE
Males (%)13 (68)24 (69)22 (67)12 (63)11 (31)0.01
Age (years)a66.9 (8.8)64.5 (9.1)64.1 (9.0)70.8 (6.7)61.4 (7.3)0.002
Disease duration (years)1 (0.6; 3)10 (2; 25)7 (1; 29)
UPDRS-III score20 (8; 41)24 (5; 49)35 (12; 70)0.01
NMSS total score42 (24; 86)69 (12; 119)0.08
PDCRS total score74 (58; 112)80 (43; 109)0.91

[i] Values are expressed in medians (interquartile range) otherwise specified a = mean (Standard deviation). Parkinson’s disease (PD) (total sample = 35) measured in the ON state (ON-PD) (n = 35) and OFF state (OFF-PF), (n = 33); ET = Essential Tremor; UPDRS = Unified Parkinson’s disease Rating Scale; NMSS = Non motor symptoms severity score: PDCRS = Parkinson’s disease cognitive rating scale. Data were compared using the ANOVA test.

In Table 2, the values of α-Synuclein are quoted in ng/ml. The label of the first cell of the last row is ‘Pairwise comparisons’ and should read (1) vs. (5), (2) vs. (4), and (3) vs. (5) (second cell), (1) vs. (2) and (1) vs. (3) (third cell) and (1) vs. (2), (1) vs. (4), and (3) vs. (4) (fifth cell).

Table 2

Plasma α-synuclein quantitation (ng/ml) stratified by age and gender.

GROUPSα-SYNUCLEIN (ng/ml)
MEAN ± SD
p-VALUEα-SYNUCLEIN (ng/ml)
MEAN ± SD
P-VALUE
MEN
(n)
WOMEN
(n)
<66 YEARS OLD
(n)
≥66 YEARS OLD
(n)
CONTROL (1)158.40 ± 102.95
(11)
177.12 ± 86.53
(24)
0.57174.81 ± 94.85
(25)
162.32 ± 84.18
(10)
0.71
ON-PD (2)112.30 ± 56.63
(23)
111.08 ± 40.45
(10)
0.95125.76 ± 56.77
(17)
97.24 ± 42.45
(16)
0.11
OFF-PD (3)128.64 ± 46.37
(21)
127.26 ± 29.16
(10)
0.92137.40 ± 43.43
(16)
118.37 ± 37.40
(15)
0.20
NOVO-PD (4)91.92 ± 35.28
(13)
131.25 ± 50.01
(6)
0.0690.21 ± 26.38
(7)
112.58 ± 49.91
(12)
0.21
ET (5)79.74 ± 32.11
(12)
143.73 ± 71.89
(6)
0.0854.33 ± 1.95
(2)
106.92 ± 56.94
(16)
Pairwise comparisons(1) vs. (5)(2) vs. (4)(3) vs. (5)(1) vs. (2)(1) vs. (3)<0.05*(1) vs. (2)(1) vs. (4)(3) vs. (4)n.s<0.05*

[i] SD = Standard deviation. Age was stratified based on the median distribution of the total sample. * Pairwise intra-group comparisons as indicated in each column; n.s = not significant.

The correct tables are included here.

This information was not included correctly in the final versions sent by the authors.

Competing interests

The authors have no competing interests to declare.

DOI: https://doi.org/10.5334/tohm.637 | Journal eISSN: 2160-8288
Language: English
Submitted on: Jun 8, 2021
Accepted on: Jun 8, 2021
Published on: Jun 25, 2021
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2021 Silvia M. Albillos, Olimpio Montero, Sara Calvo, Berta Solano, José María Trejo, Esther Cubo, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.