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Ensuring Knowledge Transfer: The Critical Role of “What-If” Discussions in Virtual Patient Simulation Cover

Ensuring Knowledge Transfer: The Critical Role of “What-If” Discussions in Virtual Patient Simulation

Open Access
|Aug 2026

Figures & Tables

Figure 1

Study design.

Table 1

Descriptives of the survey scales on student perceptions of learning and knowledge transfer.

CATEGORYITEMS (n)MEANSDCRONBACH’S α
Overall experience14.480.51
Role modelling44.440.390.50
Practice with varied cases44.350.610.57
“What-if” discussion73.760.810.90
Knowledge transfer34.330.700.74

[i] Note. All items were rated on a 5-point Likert scale (1 = strongly disagree to 5 = strongly agree).

Table 2

Learning outcome (n = 21).

QUESTIONMEDIAN (PRE-TEST - CASE B&C)MEDIAN (POST-TEST NEAR - CASE D)MEDIAN (POST-TEST FAR - CASE E)WILCOXON STATISTIC (W) (NEAR TRANSFER)p-VALUE (NEAR TRANSFER)WILCOXON STATISTIC (W) (FAR TRANSFER)p-VALUE (FAR TRANSFER)EFFECT SIZE (NEAR TRANSFER)EFFECT SIZE (FAR TRANSFER)
Q1 What is your first impression of the patient? (Max: 4)334290.1280.0070.390.73
Q2 Pick the examinations you need for diagnosing the patient (Max:4)3.3344290.2540.50.450.320.20
Q3 Please describe the rationale for each test (Max: 4)33322.50.10330.210.450.33
Q4 What is the T, N, and M stage of this tumour? (Max: 4)44400.088.50.160.930.47
Q5 Please conclude the tumour stage and write down the reasoning behind it (Max: 4)23414<0.00112.5<0.0010.750.78
Q6 Which treatment should be treatment of the first choice, according to the patient’s characteristics and TNM-stage? (Max 4)44460.171810.510
Total (Max 24)19202177.00.1941.50.0180.300.53
Average (Max 4)3.173.333.5
DOI: https://doi.org/10.5334/pme.2363 | Journal eISSN: 2212-277X
Language: English
Page range: 633 - 643
Submitted on: Dec 19, 2025
Accepted on: Apr 29, 2026
Published on: Aug 5, 2026
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services

© 2026 Zhien Li, Maryam Asoodar, Tom Keulers, Desirée Joosten-ten Brinke, Diana Dolmans, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.