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Wearable Movement Data as a Potential Digital Biomarker for Chronic Pain: An Investigation Using Deep Learning Cover

Wearable Movement Data as a Potential Digital Biomarker for Chronic Pain: An Investigation Using Deep Learning

Open Access
|Apr 2024

Figures & Tables

paah-8-1-329-g1.png
Figure 1

Data Processing with Artifact Correction Algorithm and Savgol Filter.

A schematic of the activity over a week for a participant is shown, where each participant was selected as a chronic pain participant (n = 688) or non-chronic pain participant (n = 3552). The data was then processed using an artifact correction algorithm, smoothed using a Savgal-Golay filter and standardized with a min-max scalar, which resulted in an overall reduction in noise.

paah-8-1-329-g2.png
Figure 2

Convolutional Long Short-Term Memory (LSTM) Model Diagram.

A diagram of the data processing for the convolutional LSTM model is provided in Figure 2. The data (model input in figure) was shaped into a 7 day by 24 hour (y-axis) by 60 minute (x-axis) for each participant. These seven daily activity logs were then fed into the Conv LSTM layers and into dense layers to make a final model prediction.

Table 1

Sociodemographic information from the NHANES 2003–2004 cohort with Physical Activity and Chronic Pain data.

NO CHRONIC PAINCHRONIC PAIN
Race and Ethnicity
Mexican American77697
Other Hispanic1149
Non-Hispanic White1817436
Non-Hispanic Black697116
Other Race-Including Multi-Racial14830
Gender
Male1768278
Female1784410
Age
<2000
20–3070163
30–40577113
40–50573126
50–60411124
60–70534135
70–84591101
>8500
paah-8-1-329-g3.png
Figure 3

AUC Curve of False Positive vs False Negative Rate. AUC, Area Under the Curve.

The AUC curve represents the interaction between sensitivity and 1-specificity to show the overall predictability of the model (AUC val = 0.60, AUC test = 0.57).

Table 2

Modeling Performance of the Conv-LSTM Model with Physical Activity and Chronic Pain.

AUCSENSITIVITYSPECIFICITYPPVNPV
Validation0.600.620.5722.4788.96
Test0.570.550.6121.5787.44
DOI: https://doi.org/10.5334/paah.329 | Journal eISSN: 2515-2270
Language: English
Submitted on: Dec 22, 2023
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Accepted on: Mar 1, 2024
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Published on: Apr 25, 2024
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2024 Hannah Dorris, Jenny Oh, Nicholas Jacobson, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.