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Metastasis of Breast Cancer Promoted by Circadian Rhythm Disruption due to Light/Dark Shift and its Prevention by Dietary Quercetin in Mice Cover

Metastasis of Breast Cancer Promoted by Circadian Rhythm Disruption due to Light/Dark Shift and its Prevention by Dietary Quercetin in Mice

Journal of Circadian Rhythms
Volume 19 (2021): Issue 1
By: Minoru Numata,  Akane Hirano,  Yukika Yamamoto,  Michiko Yasuda,  Nobuhiko Miura,  Kazutoshi Sayama,  Masa-Aki Shibata,  Tomohiro Asai,  Naoto Oku,  Noriyuki Miyoshi and  Kayoko Shimoi  
Open Access
|Feb 2021

References

  1. 1Cajochen C, Krauchi K, Wirz-Justice A. Role of melatonin in the regulation of human circadian rhythms and sleep. J Neuroendocrinol. 2003; 15(4): 432–437. DOI: 10.1046/j.1365-2826.2003.00989.x
    Back to article
  2. 2Mancia G, Ferrari A, Gregorini L, Parati G, Pomidossi G, Bertinieri G, et al. Blood pressure and heart rate variabilities in normotensive and hypertensive human beings. Circ Res. 1983; 53: 96–104. DOI: 10.1161/01.RES.53.1.96
    Back to article
  3. 3Suzuki S, Toyabe S, Moroda T, Tada T, Tsukahara A, Iiai T, et al. Circadian rhythm of leucocytes and lymphocytes subsets and its possible correlation with the function of the autonomic nervous system. Clin Exp Immunol. 1997; 110(3): 500–508. DOI: 10.1046/j.1365-2249.1997.4411460.x
    Back to article
  4. 4Okamura H. Clock genes in cell clocks: roles, actions, and mysteries. J Biol Rhythms. 2004; 19(5): 388–399. DOI: 10.1177/0748730404269169
    Back to article
  5. 5Aoshima Y, Sakakibara H, Suzuki T, Yamazaki S, Shimoi K. Nocturnal light exposure alters hepatic Pai-1 expression by stimulating the adrenal pathway in C3H mice. Exp Anim. 2014; 63(3): 331–338. DOI: 10.1538/expanim.63.331
    Back to article
  6. 6Hickie IB, Naismith SL, Robillard R, Scott EM, Hermens DF. Manipulating the sleep-wake cycle and circadian rhythms to improve clinical management of major depression. BMC Med. 2013; 11: 79. DOI: 10.1186/1741-7015-11-79
    Back to article
  7. 7Ishida A, Mutoh T, Ueyama T, Bando H, Masubuchi S, Nakahara D, et al. Light activates the adrenal gland: Timing of gene expression and glucocorticoid release. Cell Metab. 2005; 2(5): 297–307. DOI: 10.1016/j.cmet.2005.09.009
    Back to article
  8. 8Mohawk JA, Pargament JM, Lee TM. Circadian dependence of corticosterone release to light exposure in the rat. Physiol Behav. 2007; 92(5): 800–806. DOI: 10.1016/j.physbeh.2007.06.009
    Back to article
  9. 9Mukherji A, Kobiita A, Chambon P. Shifting the feeding of mice to the rest phase creates metabolic alterations, which, on their own, shift the peripheral circadian clocks by 12 hours. Proc Natl Acad Sci USA. 2015; 112(48): e6683–e6690. DOI: 10.1073/pnas.1519735112
    Back to article
  10. 10Yeh CM, Shay J, Zeng TC, Chou JL, Huang TH, Lai HC, et al. Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer. Int J Oncol. 2014; 45(5): 2101–2107. DOI: 10.3892/ijo.2014.2627
    Back to article
  11. 11Zeng ZL, Luo HY, Yang J, Wu WJ, Chen DL, Huang P, et al. Overexpression of the circadian clock gene bmal1 increases sensitivity to oxaliplatin in colorectal cancer. Clin Cancer Res. 2014; 20(4): 1042–1052. DOI: 10.1158/1078-0432.CCR-13-0171
    Back to article
  12. 12Hsu CM, Lin SF, Lu CT, Lin PM, Yang MY. Altered expression of circadian clock genes in head and neck squamous cell carcinoma. Tumour Biol. 2012; 33: 149–155. DOI: 10.1111/j.1749-4486.2010.02231.x
    Back to article
  13. 13Yang X, Wood PA, Oh EY, Du-Quiton J, Ansell CM, Hrushesky WJ. Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm. Breast Cancer Res Treat. 2009; 117(2): 423–431. DOI: 10.1007/s10549-008-0133-z
    Back to article
  14. 14Fitzmaurice C, Allen C, Barber RM, Barregard L, Bhutta ZA, Brenner H, et al. Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived with Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015: A Systematic Analysis for the Global Burden of Disease Study. JAMA Oncol. 2017; 3(4): 524–548. DOI: 10.1001/jamaoncol.2016.5688
    Back to article
  15. 15Schernhammer ES, Laden F, Speizer FE, Willett WC, Hunter DJ, Kawachi I, et al. Rotating night shifts and risk of breast cancer in women participating in the nurses’ health study. J Natl Cancer Inst. 2001; 93(20): 1563–1568. DOI: 10.1093/jnci/93.20.1563
    Back to article
  16. 16Erdem JS, Notø HØ, Skare Ø, Lie JS, Petersen-Øverleir M, Reszka E, et al. Mechanisms of breast cancer risk in shift workers: Association of telomere shortening with the du-ration and intensity of night work. Cancer Med. 2017; 6(8): 1988–1997. DOI: 10.1002/cam4.1135
    Back to article
  17. 17Hansen J, Stevens RG. Case-control study of shift-work and breast cancer risk in Danish nurses: Impact of shift systems. Eur J Cancer. 2012; 48(11): 1722–1729. DOI: 10.1016/j.ejca.2011.07.005
    Back to article
  18. 18Rezaianzadeh A, Jalali M, Maghsoudi A, Mokhtari AM, Azgomi SH, Dehghani SL. The overall 5-year survival rate of breast cancer among Iranian women: A systematic review and meta-analysis of published studies. Breast Dis. 2017; 37(2): 63–68. DOI: 10.3233/BD-160244
    Back to article
  19. 19Szpunar MJ, Belcher EK, Dawes RP, Madden KS. Sympathetic innervation, norepinephrine content, and norepinephrine turnover in orthotopic and spontaneous models of breast cancer. Brain Behav Immun. 2016; 53: 223–233. DOI: 10.1016/j.bbi.2015.12.014
    Back to article
  20. 20Yamazaki S, Miyoshi N, Kawabata K, Yasuda M, Shimoi K. Quercetin-3-O-glucuronide inhibits noradrenaline-promoted invasion of MDA-MB-231 human breast cancer cells by blocking β2-adrenergic signaling. Arch Biochem Biophys. 2014; 557: 18–27. DOI: 10.1016/j.abb.2014.05.030
    Back to article
  21. 21Suzuki K, Hayano Y, Nakai A, Furuta F, Noda M. Adrenergic control of the adaptive immune response by diurnal lymphocyte recirculation through lymph nodes. J Exp Med. 2016; 213(12): 2567–2574. DOI: 10.1084/jem.20160723
    Back to article
  22. 22Yasuda MT, Watanabe Y, Hosono T, Seki T, Suzuki TA, Sakakibara H, Shimoi K. Nocturnal light exposure stimulates the cardiac fibrinolysis system and stress responses in C3H/He mice. Thromb Res. 2020; 180: 79–81. DOI: 10.1016/j.thromres.2020.02.003
    Back to article
  23. 23Oyama I, Kubo T, Fujino Y, Kadowaki K, Kunimoto M, Shirane K, et al. Retrospective cohort study of the risk of impaired glucose tolerance among shift workers. Scand J Work Environ Health. 2012; 38(4): 337–342. DOI: 10.5271/sjweh.3297
    Back to article
  24. 24Kazemi R, Sajad Z, Rasoul H. Comparison of melatonin profile and alertness of firefighters with different work schedules. J Circadian Rhythms. 2018; 16(1): 1–7. DOI: 10.5334/jcr.155
    Back to article
  25. 25Jongwoo K. The relationship between frequency of injuries and workplace environment in Korea: Focus on shift work and workplace environmental factors. Saf Health Work. 2018; 9(4): 421–426. DOI: 10.1016/j.shaw.2018.01.006
    Back to article
  26. 26Ito Y, Shibata MA, Eid N, Morimoto J, Otsuka Y. Lymphangiogenesis and axillary lymph node metastases correlated with VEGF-C expression in two immunocompetent mouse mammary carcinoma models. Int J Breast Cancer. 2011; 2011: 867152. DOI: 10.4061/2011/867152
    Back to article
  27. 27Hong X, Cui B, Wang M, Yang Z, Wang L, Xu Q. Systemic Immune-inflammation Index, Based on Platelet Counts and Neutrophil-Lymphocyte Ratio, Is Useful for Predicting Prognosis in Small Cell Lung Cancer. Tohoku J Exp Med. 2015; 236: 297–304. DOI: 10.1620/tjem.236.297
    Back to article
  28. 28Minardi D, Scartozzi M, Montesi L, Santoni M, Burattini L, Bianconi M, et al. Neutrophil-to-lymphocyte ratio may be associated with the outcome in patients with prostate cancer. SpringerPlus. 2015; 4: 255. DOI: 10.1186/s40064-015-1036-1
    Back to article
  29. 29Grosso G, Godos J, Lamuela-Raventos R, Ray S, Micek A, Pajak A, et al. A comprehensive meta-analysis on dietary flavonoid and lignan intake and cancer risk: Level of evidence and limitations. Mol Nutr Food Res. 2017; 61(4): DOI: 10.1002/mnfr.201600930
    Back to article
  30. 30Yao LH, Jiang YM, Shi J, Tomás-Barberán FA, Datta N, Singanusong R, et al. Flavonoids in food and their health benefits. Plant Foods Hum Nutr. 2004; 59(3): 113–122. DOI: 10.1007/s11130-004-0049-7
    Back to article
  31. 31Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993; 342(8878): 1007–1011. DOI: 10.1016/0140-6736(93)92876-U
    Back to article
  32. 32Dihal AA, de Boer VC, van der Woude H, Tilburgs C, Bruijntjes JP, Alink GM, et al. Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats. J Nutr. 2006; 136(11): 2862–2867. DOI: 10.1093/jn/136.11.2862
    Back to article
  33. 33Shibata MA, Shibata E, Morimoto J, Eid Nabil AS, Tanaka Y, Watanabe M, et al. An immunocompetent murine model of metastatic mammary cancer accessible to bioluminescence imaging. Anticancer Res. 2009; 29(11): 4389–4395.
    Back to article
  34. 34Ohtani K, Ashimori A, Yanagiba Y, Yoshioka H, Hasegawa T, Hwang GW, et al. Combined effect of circadian dysfunction and cadmium on immune suppression. Fundam Toxicol Sci. 2016; 3(5): 237–242. DOI: 10.2131/fts.3.237
    Back to article
  35. 35Shibata MA, Hamaoka H, Morimoto J, Kanayama T, Maemura K, Ito Y, et al. Synthetic a-mangostin dilaurate strongly suppresses wide-spectrum organ metastasis in a mouse model of mammary cancer. Cancer Sci. 2018; 109(5): 1660–1671. DOI: 10.1111/cas.13590
    Back to article
  36. 36Yuan X, Zhu C, Wang M, Mo F, Du W, Ma X. Night Shift Work Increases the Risks of Multiple Primary Cancers in Women: A Systematic Review and Meta-analysis of 61 Articles. Cancer Epidemiol Biomarkers Prev. 2019; 28(2): 423. DOI: 10.1158/1055-9965.EPI-18-1085
    Back to article
  37. 37Morales-Santana S, Morell S, Leon J, Carazo-Gallego A, Jimenez-Lopez JC, Morell M. An Overview of the Polymorphisms of Circadian Genes Associated with Endocrine Cancer. Front Endocrinol. 2019; 10: 104. DOI: 10.3389/fendo.2019.00104
    Back to article
  38. 38Ruszkowaka-Ciastek B, Rhone P, Bielawski K, Zarychta E, Rosc D, Nava E. Divergent Impact of Breast Cancer Laterality on Clinicopathological, Angiogenic, and Hemostatic Profiles: A Potential Role of Tumor Localization in Future Outcomes. J Clin Med. 2020; 9(6): 1708. DOI: 10.3390/jcm9061708
    Back to article
  39. 39Yang X, Wood PA, oh EY, Du-Quiton J, Ansell CM, Hrushesky WJM. Down regulation of circadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm. Breast Cancer Res Treat. 2009; 117: 423–431. DOI: 10.1007/s10549-008-0133-z
    Back to article
  40. 40Humphries BA, Buschhaus JM, Chen YC, Haley HR, Qyli T, Chiang B, et al. Plasminogen Activator Inhibitor 1 (PAI1) Promotes Actin Cytoskeleton Reorganization and Glycolytic Metabolism in Triple-Negative Breast Cancer. Mol Cancer Res. 2019; 17(5): 1142–1154. DOI: 10.1158/1541-7786.MCR-18-0836
    Back to article
  41. 41Almholt K, Nielsen BS, Frandsen TL, Brünner N, Danø K, Johnsen M. Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice. 2003; 22: 4389–4397. DOI: 10.1038/sj.onc.1206601
    Back to article
  42. 42Eva H, William T, Xiao-Mei L, Yetki A, Marthe V, Julie R, et al. Chronic Circadian Disruption Modulates Breast Cancer Stemness and Immune Microenvironment to Drive Metastasis in Mice. Nat Commun. 2020; 11: 3193. DOI: 10.1038/s41467-020-16890-6
    Back to article
  43. 43Le CP, Nowell CJ, Kim-Fuchs C, Botteri E, Hiller JG, Ismail H, et al. Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination. Nat Commun. 2016; 7: 10634. DOI: 10.1038/ncomms10634
    Back to article
  44. 44Obi-Ioka Y, Ushijima K, Kusama M, Ishikawa-Kobayashi E, Fujimura A. Involvement of Wee1 in the circadian rhythm-dependent intestinal damage induced by docetaxel. J Pharmacol Exp Ther. 2013; 347: 242–248. DOI: 10.1124/jpet.113.203299
    Back to article
  45. 45Taufique SKT, Prabhat A, Kumar V. Illuminated night alters hippocampal gene expressions and induces depressive-like responses in diurnal corvids. Eur J Neurosci. 2018; 48(9): 3005–3018. DOI: 10.1111/ejn.14157
    Back to article
  46. 46Zou JM, Qin J, Li YC, Wang Y, Li D, Shu Y, et al. IL-35 induces N2 phenotype of neutrophils to promote tumor growth. Oncotarget. 2017; 8(20): 33501–33514. DOI: 10.18632/oncotarget.16819
    Back to article
  47. 47Liang W, Ferrara N. The Complex Role of Neutrophils in Tumor Angiogenesis and Metastasis. Cancer Immunol Res. 2016; 4(2): 83–91. DOI: 10.1158/2326-6066.CIR-15-0313
    Back to article
  48. 48Swierczak A, Mouchemore KA, Hamilton JA, Anderson RL. Neutrophils: important contributors to tumor progression and metastasis. Cancer Metastasis Rev. 2015; 34(4): 735–751. DOI: 10.1007/s10555-015-9594-9
    Back to article
  49. 49Kettner NM, Voicu H, Finegold MJ, Coarfa C, Sreekumar A, Putluri N, et al. Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis. Cancer Cell. 2016; 30(6): 909–924. DOI: 10.1016/j.ccell.2016.10.007
    Back to article
  50. 50Wu M, Zeng J, Chen Y, Zeng Z, Zhang J, Cai Y, et al. Experimental chronic jet lag promotes growth and lung metastasis of Lewis lung carcinoma in C57BL/6 mice. Oncol Rep. 2012; 27(5): 1417–1428. DOI: 10.3892/or.2012.1688
    Back to article
  51. 51Oshima H, Nakayama M, Han TS, Naoi K, Ju X, Maeda Y, et al. Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer. Cancer Res. 2015; 75(4): 766–776. DOI: 10.1158/0008-5472.CAN-14-2036
    Back to article
  52. 52Allin KH, Nordestgaard BG, Flyger H, Bojesen SE. Elevated pre-treatment levels of plasma C-reactive protein are associated with poor prognosis after breast cancer: a cohort study. Breast Cancer Res. 2011; 13(3): R55. DOI: 10.1186/bcr2891
    Back to article
  53. 53Landskron G, De la Fuente M, Thuwajit P, Thuwajit C, Hermoso MA. Chronic Inflammation and Cytokines in the Tumor Microenvironment. J Immunol Res. 2014; 2014: 149185. DOI: 10.1155/2014/149185
    Back to article
  54. 54Odle TG. Adverse effects of breast cancer treatment. Radiol Technol. 2014; 85(3): 297M–319M.
    Back to article
  55. 55Khorsandi L, Orazizadeh M, Niazvand F, Abbaspour MR, Mansouri E, Khodadadi A. Quercetin induces apoptosis and necroptosis in MCF-7 breast cancer cells. Bratisl Lek Listy. 2017; 118(2): 123–128. DOI: 10.4149/BLL_2017_025
    Back to article
  56. 56Jia L, Huang S, Yin X, Zan Y, Guo Y, Han L. Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction. Life Sci. 2018; 208: 123–130. DOI: 10.1016/j.lfs.2018.07.027
    Back to article
  57. 57Baruah MM, Khandwekar AP, Sharma N. Quercetin modulates Wnt signaling components in prostate cancer cell line by inhibiting cell viability, migration, and metastases. Tumour Biol. 2016; 37(10): 14025–14034. DOI: 10.1007/s13277-016-5277-6
    Back to article
  58. 58Teekaraman D, Elayapillai SP, Viswanathan MP, Jagadeesan A. Quercetin inhibits human metastatic ovarian cancer cell growth and modulates components of the intrinsic apoptotic pathway in PA-1 cell line. Chem Biol Interact. 2019; 300: 91–100. DOI: 10.1016/j.cbi.2019.01.008
    Back to article
  59. 59de Boer VC, Dihal AA, van der Woude H, Arts IC, Wolffram S, Alink GM, et al. Tissue distribution of quercetin in rats and pigs. J Nutr. 2005; 135(7): 1718–1725. DOI: 10.1093/jn/135.7.1718
    Back to article
  60. 60Nakamura T, Kinjo C, Nakamura Y, Kato Y, Nishikawa M, Hamada M, et al. Lymphatic metabolites of quercetin after intestinal administration of quercetin-3-glucoside and its aglycone in rats. Arch Biochem Biophys. 2018; 645: 126–136. DOI: 10.1016/j.abb.2018.03.024
    Back to article
DOI: https://doi.org/10.5334/jcr.203 | Journal eISSN: 1740-3391
Journal RSS Feed
Language: English
Submitted on: Nov 7, 2020
Accepted on: Jan 31, 2021
Published on: Feb 18, 2021
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
light/dark shift,
circadian rhythm,
breast cancer,
lymph node metastasis,
quercetin

© 2021 Minoru Numata, Akane Hirano, Yukika Yamamoto, Michiko Yasuda, Nobuhiko Miura, Kazutoshi Sayama, Masa-Aki Shibata, Tomohiro Asai, Naoto Oku, Noriyuki Miyoshi, Kayoko Shimoi, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.

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