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Clival Infiltrative Lesions: A Review of Differential Diagnosis Illustrated by a Rare Case of Coexisting Invasive Pituitary Adenoma and Clival Intravascular Lymphoma Cover

Clival Infiltrative Lesions: A Review of Differential Diagnosis Illustrated by a Rare Case of Coexisting Invasive Pituitary Adenoma and Clival Intravascular Lymphoma

Open Access
|Dec 2025

Abstract

Pituitary adenoma, a common benign tumor that can invade the clivus or appear ectopically, poses diagnostic challenges. Intravascular lymphoma is extremely rare and frequently underdiagnosed. A case is presented of coexisting pituitary adenoma and clival intravascular large B‑cell lymphoma, highlighting the differential diagnosis of clival infiltrative lesions.

Teaching point: Clival lesions present a wide diagnostic spectrum; when imaging findings are atypical, histopathology remains essential for definitive diagnosis and appropriate treatment.

DOI: https://doi.org/10.5334/jbsr.4102 | Journal eISSN: 2514-8281
Language: English
Submitted on: Sep 13, 2025
Accepted on: Nov 20, 2025
Published on: Dec 11, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Eva Van Pée, Lina Daoud, Idil Gunes Tatar, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.