Table 1
Characteristics of the breasts analyzed.
| AGE | BREAST COMPOSITION | CANCER (N = 52) | HISTOLOGICALLY BENIGN (N = 28) |
|---|---|---|---|
| 31–82 years (median: 45 years) | A: 1 /B: 22 /C: 57 /D: 13 Dense breast 70 (75.3%) | DCIS 9 (17.3%) IDC 43 (82.7%) | Fibroadenoma 7 Intraductal papilloma 2 Apocrine metaplasia 1 Hemangioma 1 Phyllodes tumor 1 Negative 16 |
[i] 186 breasts in 93 nationality women.
A. fatty, B. scattered fibroglandular densities, C. heterogeneously dense, D. extremely dense, DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma; Negative, no indication of cancer.
Figure 1
Two sequential modes were full-field digital mammography (FFDM) followed by FFDM/digital breast tomosynthesis (DBT) (Group 1), and two-dimensional synthetic mammography (SM) followed by SM/DBT (Group 2). FFDM/DBT and SM/DBT were compared using Fisher’s exact test.
Table 2
Radiation dose for image acquisition.
| RADIATION DOSE (MGY) | MEDIAN | ||
|---|---|---|---|
| FFDM | MLO | 0.69–6.29 | |
| CC | 0.70–6.18 | 1.47 | |
| DBT (=SM/DBT) | MLO | 0.92–5.43 | |
| CC | 0.93–5.03 | 1.50 | |
| FFDM/DBT | MLO | 1.64–11.72 | |
| CC | 1.63–11.21 | 2.95 |
[i] FFDM, full-field digital mammography; DBT, digital breast tomosynthesis; SM, two-dimensional synthetic mammography; MLO, mediolateral oblique; CC, craniocaudal.
Table 3
Inter-rater reliability with Cohen’s Kappa coefficients.
| COMPARISON | COHEN’S KAPPA COEFFICIENTS | |
|---|---|---|
| Readers | I and II reading FFDM/DBT | 0.780 (substantial agreement) |
| III and IV reading SM/DBT | 0.773 (substantial agreement) | |
| Interpretation | FFDM/DBT and SM/DBT | 0.745 (substantial agreement) |
[i] FFDM, full-field digital mammography; DBT, digital breast tomosynthesis; SM, two-dimensional synthetic mammography.
Table 4
FFDM/DBT compared with SM/DBT for the detection of breast cancer.
| INTERPRETATION | FISHER’S EXACT TEST | ||
|---|---|---|---|
| Sensitivity | FFDM/DBT | 38/52 (73.1%) | |
| SM/DBT | 37/52 (71.2%) | p = 1.000 | |
| Specificity | FFDM/DBT | 109/134 (81.3%) | |
| SM/DBT | 111/134 (82.8%) | p = 0.874 | |
| Accuracy | FFDM/DBT | 147/186 (79.0%) | |
| SM/DBT | 148/186 (79.6%) | p = 1.000 | |
[i] FFDM, full-field digital mammography; DBT, digital breast tomosynthesis; SM, two-dimensional synthetic mammography.
Figure 2
An ill-defined mass was detected with subtle margins in the lower area of the full-field digital mammography (FFDM) mediolateral oblique (MLO) image (a) and the inner area of the FFDM craniocaudal (CC) image (b). The mass was rated unclear on the two-dimensional synthetic mammography (SM) MLO (c) and CC (d) images.
Figure 3
Segmental amorphous microcalcifications were detected in the lower area of the full-field digital mammography (FFDM) mediolateral oblique (MLO) image (a-1 and a-2), and grouped amorphous microcalcifications with distortion were detected in the inner area of the FFDM craniocaudal (CC) image (b-1 and b-2). On the two-dimensional synthetic mammography (SM) images, there were diffuse calcifications in the left breast (c-1 and d-1), which were coarse (c-2 and d-2).