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Lipid Control Post Coronary Artery Bypass Graft: One Year Follow-Up of a Middle-Eastern Cohort Cover

Lipid Control Post Coronary Artery Bypass Graft: One Year Follow-Up of a Middle-Eastern Cohort

Open Access
|Feb 2020

Figures & Tables

Table 1

Baseline characteristics of patients discharged following CABG (n = 189).

Mean ± SD/FrequencyPercentage
Age (years) 59.7 ± 10.4N/A
Nationality – Emirati 8846.6%
Gender – Male 16687.8%
    Out of Emiratis Only7382.95%
Past Medical History (Most to Least Prevalent)
    Hyperlipidemia17089.9%
    Hypertension15783.1
    Diabetes13470.9%
    Heart failure5127.0%
    Prior PCI4724.9%
    CKD (GFR <60 mL/min)3518.5%
    PVD157.9%
    Uncontrolled Hypothyroidism105.3%
    Stroke or TIA84.2%
    Prior CABG21.1%
Body Mass Index (kg/m2) 27.7 ± 4.9N/A
Smoker (current or former) 8243.4%
Presentation on Admission
    ACS12867.7%
    Stable angina6132.3%
Length of Stay (days) 8.4 ± 7.5N/A
AACE Classification
    Very high risk2814.8%
    Extremely high risk16185.2%
ACC/AHA Classification
    Clinical ASCVD3015.9%
    Very high risk ASCVD15984.1%

[i] PCI = Percutaneous Coronary Intervention, CKD = Chronic Kidney Disease, PVD = Peripheral Vascular Disease, TIA = Transient Ischemic Attack, CABG = Coronary Artery Bypass Graft, ACS = Acute Coronary Syndrome, AACE = American Association of Clinical Endocrinologists, ACC/AHA = American College of Cardiology/American Heart Association.

Table 2

Lipid panel and management of CABG patients (n = 189).

On statins prior to CABG91.0% (172)
    High intensity72.7% (125, n = 172)
        – Atorvastatin33.1% (40 mg)|18.6% (80 mg)
        – Rosuvastatin18.6% (20 mg)|3.5% (40 mg)
    Moderate intensity24.9% (47, n = 172)
        – Atorvastatin19.8%
        – Rosuvastatin6.4%
        – Other1.2%
    Combination with other agents7.6% (13, n = 172)
On statins at discharge 99.5% (188)
    High intensity93.6% (176, n = 188)
        – Atorvastatin35.6% (40 mg)|31.9% (80 g)
        – Rosuvastatin18.1% (20 g)|8.0% (40 mg)
    Moderate intensity6.4% (12, n = 188)
        – Atorvastatin2.7%
        – Rosuvastatin3.7%
    Combination with other agents5.3% (10, n = 188)
Availability of lipid panel
    At baseline59.8%
    Up to the 3 months visit (n = 175)14.3%
    Beyond 3 months visit (n = 84)51.2%
Achievement of LDL goal at any follow up beyond 3 months
    LDL ≤ 100 mg/dL86%
    LDL ≤ 70 mg/dL58.1%
    LDL ≤ 55 mg/dL**29%

[i] ** Percentage out of those deemed extremely high risk per the AACE guidelines (n = 161, 85.2%).

gh-15-1-530-g1.png
Figure 1

Percentage of CABG patients who completed a clinic visit at the different time intervals (up to 3 months and beyond 3 months) following surgery based on the specialty of the providers.

* Patients seen by a medical specialty physician (cardiology, endocrinology and/or internal medicine) might also have been seen by cardiac surgery (CTS).

gh-15-1-530-g2.png
Figure 2

Percentage of lipid panels performed and patients on high intensity statins at discharge and at follow up (beyond the first 3 months).

gh-15-1-530-g3.png
Figure 3

Percentage of patients achieving LDL goals at baseline and follow up visits (LDL in mg/dL).

Table 3

Prevalence of different interventions in patients who followed up.

0–4 Months5–8 Months9–12 MonthsBeyond 12 Months
No Intervention 93.1%92.3%81.2%87.4%
Statin Dose Increased 2.3%2.6%4.3%4.6%
Statin Dose Decreased 2.3%3.8%13.0%4.6%
Statin Switched 0.6%0.0%0.0%1.1%
Ezetimibe Added 1.7%1.3%1.4%2.3%
PCSK9 Added 0.0%0.0%0.0%0.0%
Follow Up (n = 189) 175 (92.6%)78 (41.3%)69 (36.5%)87 (46.0%)
Table 4

Logistic regression model for predictors of lipid panel ordering in those who followed up beyond 3 monthsX.

VariablesEstimateStd. ErrorZp-ValueOdds Ratio95% CI Odds Ratio
minmax
Intercept 2.38 2.64 0.903 0.367    10.840.061914.30
Speciality Seen (Cardiologist)1.610.802.0080.045**4.991.0423.95
Age (Years)–0.050.03–1.7220.085*  0.960.911.01

[i] ** Statistically significant at the 95% confidence interval.

* Statistically significant at the 90% confidence interval.

X The multivariate analysis included variables of Age, Specialty Seen (CT Surgeon, Cardiologist, Endo), BMI, Nationality, Diabetes, CVD Family History, and Risk Classification per ACC/AHA Guidelines, and AACE Guidelines. Patients who followed up with a cardiologist (p > 0.05) and who were younger (p > 0.1) were more likely to have lipid panels ordered during follow up.

DOI: https://doi.org/10.5334/gh.530 | Journal eISSN: 2211-8179
Language: English
Submitted on: Aug 17, 2019
Accepted on: Jan 10, 2020
Published on: Feb 10, 2020
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2020 Bassam Atallah, Ramzi Khaddage, Ziad G. Sadik, Saad I. Mallah, Terrence J. Lee-St. John, Shamsah Alfardan, Mahmoud I. Traina, Wael Almahmeed, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.