Fifth Universal Definition of Myocardial Infarction (2026)

Cardiology and Cardiac MRI Department, Royal Brompton and Harefield Hospitals, Guys and St Thomas NHS Foundation Trust, London; National Heart and Lung Institute, Imperial College London, London; School of Biomedical Engineering and Imaging Sciences, Kings College London, London

Monica M. Colvin

editorialoffice@globalheartjournal.com

Cardiovascular Division, University of Michigan, Ann Arbor, MI

George D. Dangas

editorialoffice@globalheartjournal.com

Cardiology, Mount Sinai Medical Center, New York, NY

Holli A. DeVon

editorialoffice@globalheartjournal.com

School of Nursing, University of California Los Angeles, Los Angeles

Rohan Dharmakumar

editorialoffice@globalheartjournal.com

Cardiovascular Imaging Research Center, Medical Imaging Research Institute, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN; Division of Cardiovascular Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN

Thomas A. Gaziano

editorialoffice@globalheartjournal.com

Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, MA; Health Policy and Management, Harvard School of Public Health, Boston, MA; Medicine, Harvard Medical School, Boston, MA

Derek J. Hausenloy

editorialoffice@globalheartjournal.com

Cardiovascular and Metabolic Disorders Program, Duke-NUS Medical School, Singapore; National Heart Research Institute Singapore, National Heart Centre Singapore, SG; The Hatter Cardiovascular Institute, University College London, London

Mohamed Jeilan

editorialoffice@globalheartjournal.com

Department of Medicine, Aga Khan University Hospital, Nairobi

Konstantinos C. Koskinas

editorialoffice@globalheartjournal.com

Department of Cardiology, Bern University Hospital, Inselspital, Bern

Bertil Lindahl

editorialoffice@globalheartjournal.com

Department of Medical Sciences, Uppsala University, Uppsala

Zuzana Motovska

editorialoffice@globalheartjournal.com

Cardiocenter, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague

Maria Rubini Gimenez

editorialoffice@globalheartjournal.com

Cardiology Department, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid; Cardiology Department, Ascires Biomedical Group, Valencia

Ana María Salvati

editorialoffice@globalheartjournal.com

Cardiology, Clínica Modelo de Morón, Buenos Aires, Argentina, and Argentine Society of Cardiology, Buenos Aires

Jacqueline E. Tamis-Holland

editorialoffice@globalheartjournal.com

Cardiovascular Medicine, Cleveland Clinic, Heart, Vascular and Thoracic Institute, Cleveland, OH

ESC/ACC/AHA/WHF Universal Definition Document Advisory Group

nick.mills@ed.ac.uk

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DOI: https://doi.org/10.5334/gh.1578 | Journal eISSN: 2211-8179

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Language: English

Page range: 64 - 64

Submitted on: Jul 31, 2026

Accepted on: Jul 31, 2026

Published on: Aug 28, 2026

Published by: Ubiquity Press

In partnership with: Paradigm Publishing Services

Keywords:

Universal Definition,

Expert Consensus Document,

Myocardial infarction,

Primary myocardial infarction,

Secondary myocardial infarction,

Cardiac troponin,

High-sensitivity cardiac troponin,

Acute myocardial injury,

Chronic myocardial injury,

Unrecognized myocardial infarction,

Unstable angina,

Recurrent myocardial infarction,

Coronary and cardiac imaging,

Takotsubo syndrome,

Myocardial injury with non-obstructive coronary arteries (MINOCA),

International Classification of Diseases 11th Revision (ICD-11)

© 2026 Nicholas L. Mills, L. Kristin Newby, Sarah Zaman, Wael A. Almahmeed, Chiara Bucciarelli-Ducci, Monica M. Colvin, George D. Dangas, Holli A. DeVon, Rohan Dharmakumar, Thomas A. Gaziano, Derek J. Hausenloy, Mohamed Jeilan, Konstantinos C. Koskinas, Bertil Lindahl, Zuzana Motovska, Maria Rubini Gimenez, Ana María Salvati, Jacqueline E. Tamis-Holland, ESC/ACC/AHA/WHF Universal Definition Document Advisory Group, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 21 (2026): Issue 1