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Figures & Tables

gh-20-1-1496-g1.png
Figure 1

Variables that influence a greater probability of not receiving each of the vaccines.

Table 1

Baseline characteristics of the sample.

INFLUENZA VACCINEPNEUMOCOCCUSSARS CoV-2
N%N%N%
Vaccinated15,87174.2%7,65735.8%20,72696.9%
GenderFemale6,94363.8%4,75162.2%12,68661.2%
Male3,94636.2%2,88237.8%8,04938.8%
RegionNorth America8227.5%4926.4%1,1155.4%
Andean3,75634.4%2,61134.1%7,23134.8%
Brazil7406.8%3204.2%1,0925.3%
Caribbean1,0819.9%90911.9%3,32416.0%
Central America2,22320.4%1,81823.8%4,35821.0%
South Cone2,28420.9%1,49819.6%3,64517.6%
Job positionRetired2,82025.9%2,05626.9%5,23125.2%
Formal worker5,50350.5%3,72448.7%9,94647.9%
Informal worker2,58323.7%1,86824.4%5,58826.9%
ResidenceRural1,0559.7%7539.8%1,8859.1%
>500,000 inhabitants3,95636.3%2,73635.8%7,29935.2%
100,000 to 500,000 inhabitants1,88617.3%1,36017.8%3,52217.0%
<100,000 inhabitants1,69315.5%1,14415.0%3,11015.0%
Education levelNone620.6%420.5%1050.5%
Primary school4013.7%2363.1%9274.5%
College1,57314.4%1,08714.2%3,61717.4%
University/Technician8,87095.8%6,28396.4%16,1164.9%
Income (US dollars)<4992,77725.5%2,27029.7%6,17329.7%
500–9992,33521.4%1,54220.2%4,33820.9%
1,000–1,4991,83116.8%1,09514.3%3,15815.2%
1,500–1,9991,0449.6%7559.9%1,8338.8%
2,000–2,4998437.7%5757.5%1,4537.0%
2,500–2,9996125.6%4245.5%1,0605.1%
>30001,46413.4%98712.9%2,75013.2%
Age<202642.4%3003.9%8514.1%
>802172.0%1431.9%3761.8%
21–302,18420.0%1,80923.7%4,01219.3%
31–402,16819.9%1,46319.1%3,80318.3%
41–501,89317.4%1,17715.4%3,73518.0%
51–601,82816.8%1,12014.6%3,82918.4%
61–701,64515.1%1,09414.3%2,95314.2%
71–807076.5%5427.1%1,2065.8%
>802172.0%1431.9%3761.8%
Hypertension2,91526.7%1,90524.9%5,44226.2%
Obesity2,44722.4%1,60721.0%4,05019.5%
COPD3873.5%3254.2%6012.9%
Dyslipidemia1,64915.1%1,04913.7%2,90714.0%
gh-20-1-1496-g2.png
Figure 2

Forest Plot—Factors associated with influenza vaccination.

gh-20-1-1496-g3.png
Figure 3

Forest Plot—Factors associated with pneumococcal vaccination.

gh-20-1-1496-g4.png
Figure 4

Forest Plot—Factors associated with COVID-19 vaccination.

Table 1

Description of the questions included in the survey.

QUESTIONSPOSSIBLE RESPONSES
Region1. North, Central America and the Caribbean
2. Andean
3. Southern Cone
Age
Gender1. Female
2. Male
3. Transgender
4. Other
What perception do you have of your state of health?Scale of 1–10 (Unhealthy to Very healthy)
Number of inhabitants city/town of residence1. <10,000 population
2. 10,000–100,000 population
3. 100,000–500,000 population
4. >500,000 population
5. Don’t know
Marital relationship1. Married
2. Divorced
3. Single
4. United to
5. Widower
6. None of the above
Work relationship7. Dependent asset
8. Independent asset
9. Retired/Pensioned/Retired
10. Independent worker
11. Irregular worker
12. None of the above
Education level13. None
14. Primary
15. Secondary
16. University
17. Master’s degree
If you are a professional, could you describe your occupation?18. Lawyer
19. Business Administration
20. Architect
21. Engineer
22. Entrepreneur
23. Finance
24. Doctor
25. Marketing/Advertising
26. Business
27. Health area personnel
28. Others
Economic income in US dollars per month1. <499
2. 500–999
3. 1000–1499
4. 1500–1999
5. 2000–2499
6. 2500–2999
7. >3000
Access to health services1. Private with direct payment
2. Private with medical insurance
3. Social Security
4. Public Health Service
5. None
What Chronic Diseases do you have?1. Cancer
2. Mellitus diabetes
3. Diseases of the immune System
4. Psychiatric mental illness
5. Psychological
6. Chronic lung diseases
7. Renal disease
8. Fatty liver
9. Arterial hypertension
10. Hypothyroidism
11. Polycystic ovary
12. Cholesterol and/or triglyceride problems
13. Overweight/Obesity
14. Smoking
15. None of the above
Have you been diagnosed by a doctor with the following diseases?1. Angina pectoris
2. Arrhythmias
3. Disease of the arteries of the lower limbs and/or aorta
4. Stroke
5. Myocardial infarction
6. Heart failure
7. None of the above
Have you had any of the following procedures?1. Cardiac catheterization with stent placement in any coronary artery
2. Cardiac surgery for heart valve prostheses
3. Bypass surgery or revascularization of the coronary arteries
4. Lower limb vascular surgery
5. Pacemaker
6. None of the above
For his chronic illnesses, I take my medications1. Every day without fail, at the corresponding time
2. Every day without fail, but not at the corresponding time
3. I remember from time to time
4. I forget from time to time
5. I don’t take them
6. I don’t need medication
How many medications do you take?1. 1
2. 2
3. 3
4. 4
5. 5
6. More than 5
7. None
8. I don’t like taking medications
Please select your medication scheme1. Single-drug pills
2. One pill with two medications
3. One pill with three medications
4. They told me it’s called Polypill
5. None of the above
Have you had the flu?1. Yes
2. No
3. Don’t know
Have you had pneumococcus infection?4. Yes
5. No
6. Don’t know
How confident are you in the influenza vaccination?Scale 1–10 (Not at all confident to Very confident)
How confident are you in the pneumococcus vaccination?Scale 1–10 (Not at all confident to Very confident)
How often do you get the influenza vaccine?1. Annually in season
2. Every 2 years
3. Every 3 years
4. When I remember
5. From time to time
6. I don’t put it on
Have you had a pneumococcus vaccine?1. Yes
2. No
Who prescribes the vaccines?1. General Physician
2. Internal Medicine
3. Family Medicine
4. Cardiologist
5. Endocrinologist
6. Geriatrician
7. Gynecologist
8. Pulmonologist
9. Neurologist
10. Pediatrician for my children/grandchildren
11. Others (gastroenterologist, rheumatologist, etc.)
12. I prescribe myself
13. None of the above
What health service does vaccination provide you?1. Public
2. Private
3. Social Security
4. Annual vaccination campaign in my country
5. I buy it at the pharmacy without prescription
6. None of the above
How much do you know about the cardiovascular benefits of vaccination?Scale 1–10 (I don’t know them to I know them)
If you are not a doctor, do you suggest other Vaccinations?1. Yes
2. No
3. Does not apply
If you are a doctor, do you indicate vaccination for Influenza and Pneumococcus?1. Yes
2. No
3. Does not apply
Do you know when the influenza season is in your country?1. Yes
2. No
Are there vaccination campaigns for influenza and pneumococcus in your country?1. Yes
2. No
3. Don’t know
Have you been vaccinated for COVID-19?1. Yes
2. No
Number of doses given1. 1
2. 2
3. 3
4. 4
5. 5
6. None
7. All necessary
What type of vaccine do you use?1. Abdala (Cuban)
2. Moderna
3. J&J/Janssen
4. Oxford/Astra Zeneca
5. Pfizer/BioNTech
6. Sinopharm (China)
7. Sinovac/Biotech (China)
8. Sputnik 5 (Russia)
9. None
How confident are you in the COVID-19 vaccination?Scale 1–10 (Not at all confident to Very confident)
gh-20-1-1496-g5.png
Figure 1

Distribution of participating countries by region.

  1. North, Central, and Caribbean region (NCC): Mexico, Guatemala, El Salvador, Honduras, Nicaragua, Costa Rica, Panama, Cuba, Puerto Rico, and Dominican Republic.

  2. Andean region (AR): Venezuela, Colombia, Ecuador, Bolivia, and Perú.

  3. Southern Cone region (SCR): Paraguay, Chile, Uruguay, and Argentina

DOI: https://doi.org/10.5334/gh.1496 | Journal eISSN: 2211-8179
Language: English
Submitted on: Sep 18, 2025
Accepted on: Nov 24, 2025
Published on: Dec 5, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Fernando Wyss, Ricardo Lopez-Santi, Daniel Piskorz, Horacio Márquez Gonzalez, Lucelli Yañez Gutierrez, Shyla Gupta, Ana Munera-Echeverri, Pilar Lopez Santi, Gonzalo Piskorz, Vladimir Ullauri, Juan Esteban Gomez, Mildren del Sueldo, Claudia Almonte, Máxima Mendez, Osiris Valdez, Carlos Ignacio Ponte-Negretti, María Alayde Mendoça Rivera, Iván Romero Rivera, Adriana Puente Barragan, Raúl Villar, Julio Effio, Jorge Alberto Rivera Pineda, Percy Berrospi, Ana Isabel Barrientos, Nancy Silvera, Edmundo Jordan, Shirley Alejandrina Xiloj Lopez, Daniel Quezada, Ariel Arguello, Gonzalo Perez, Adrián Baranchuk, On Behalf of The CorVacc Study investigators, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.