Abstract
Medication adherence among heart failure (HF) patients in the Middle East remains a critical, under-explored issue. This systematic review examines medication adherence rates and their influencing factors in this region. A search of PubMed, Scopus, and Google Scholar identified 12 studies published between 2013 and 2023, revealing an average non-adherence rate of 60%. Influential factors include socioeconomic status, education, psychiatric conditions, and medication-related issues. Significant gaps in research methodologies and reporting were noted. The review highlights the impact of socio-economic determinants on adherence and calls for more robust research and targeted interventions to address these barriers. Improving patient education and healthcare provider communication are crucial to enhancing adherence rates. These findings underscore the importance of addressing regional challenges through tailored approaches and suggest further studies are needed to develop effective strategies for improving adherence among HF patients in the Middle East.