Table 1
Descriptive Statistics for Demographics and Clinical Characteristics.
| CONTINUOUS VARIABLE | OVERALL (M, SD) | OCD (M, SD) | HC (M, SD) |
|---|---|---|---|
| Age, years | 35.42 (13.46) | 34.89 (14.41) | 35.90 (13.31) |
| DOCS Total | 17.00 (16.98) | 20.80 (17.99) | 13.20 (15.91) |
| MIS Score | 7.00 (6.33) | 5.90 (5.92) | 8.38 (6.97) |
| BAI Total | 13.55 (13.34) | 13.30 (11.87) | 13.80 (15.32) |
| BDI-II Total | 11.50 (13.34) | 16.00 (14.50) | 7.00 (10.98) |
| CATEGORICAL VARIABLES | N (%) | n(%) | n (%) |
| Sex | |||
| Male | 13 (65.0%) | 6 (60.0%) | 7 (70.0%) |
| Female | 7 (35.0%) | 4 (40.0%) | 3 (30.0%) |
| Education Level | |||
| Some College | 2 (10.0%) | 2 (20.0%) | 0 (0.0%) |
| Bachelor Degree | 2 (10.0%) | 2 (20.0%) | 0 (0.0%) |
| Master’s Degree | 1 (5.0%) | 0 (0.0%) | 1 (10.0%) |
| Doctoral Degree | 6 (30.0%) | 4 (40.0%) | 2 (20.0%) |
| Other/Professional | 9 (45.0%) | 2 (20.0%) | 7 (70.0%) |
[i] Note: N = 20 total; n = 10 participants in each group. HC = Healthy Control; OCD = Obsessive-Compulsive Disorder; DOCS: Dimensional Obsessive-Compulsive Scale; MIS: Magical Ideation Scale; BAI: Beck Anxiety Inventory; BDI-II: Beck Depression Inventory-II.
Table 2
Subject-Level Classification Performance of the CNN.
| CLASS | PRECISION | RECALL | F1-SCORE | SUPPORT |
|---|---|---|---|---|
| HC (0) | 0.89 | 0.80 | 0.84 | 10 |
| OCD (1) | 0.82 | 0.90 | 0.86 | 10 |
| Accuracy | – | – | 0.85 | 20 |
| Macro Avg | 0.85 | 0.85 | 0.85 | 20 |
| Wtd Avg | 0.85 | 0.85 | 0.85 | 20 |
Figure 1
Subject-Level CNN Performance. (Left) The confusion matrix for subject-level predictions (N = 20). (Right) The Receiver Operator Curve (ROC) for the subject-level EEG scores, with an Area Under the Curve (AUC) of 0.88.
Table 3
Subject-Level Classification Performance of the SVM.
| CLASS | PRECISION | RECALL | F1-SCORE | SUPPORT |
|---|---|---|---|---|
| HC (0) | 0.45 | 0.50 | 0.47 | 10 |
| OCD (1) | 0.44 | 0.40 | 0.42 | 10 |
| Accuracy | – | – | 0.45 | 20 |
| Macro Avg | 0.45 | 0.45 | 0.45 | 20 |
| Wtd Avg | 0.45 | 0.45 | 0.45 | 20 |
[i] Notes: Performance metrics are calculated based on one prediction per subject (N = 20).
Figure 2
Subject-Level SVM Performance. (Left) The confusion matrix for subject-level predictions (N = 20). (Right) The receiver operator curve for the subject-level EEG scores, with an area under the curve (AUC) of 0.47, indicating chance-level performance.
Table 4
Predictive Performance for CNN + Clinical and Demographic Features.
| FEATURE | N | AUC | ACCURACY | PRECISION | RECALL | F1 | CHANGE (AUC) |
|---|---|---|---|---|---|---|---|
| Baseline EEG | 20 | 0.86 | 0.80 | 0.80 | 0.80 | 0.80 | – |
| DOCS Total | 20 | 0.86 | 0.80 | 0.80 | 0.80 | 0.80 | None |
| MIS Score | 18 | 0.81 | 0.78 | 0.75 | 0.75 | 0.75 | Worse |
| BAI Total | 20 | 0.86 | 0.80 | 0.80 | 0.80 | 0.80 | None |
| BDI-II Total | 20 | 0.84 | 0.80 | 0.80 | 0.80 | 0.80 | Worse |
| Age | 19 | 0.76 | 0.79 | 0.80 | 0.80 | 0.80 | Worse |
| Sex | 20 | 0.81 | 0.80 | 0.80 | 0.80 | 0.80 | Worse |
| Education | 20 | 0.84 | 0.80 | 0.80 | 0.80 | 0.80 | Worse |
[i] Note: Baseline metrics include only the convolutional neural network’s subject-level EEG scores in the second stage. N = number of subjects remaining after handling missing values. DOCS: Dimensional Obsessive-Compulsive Scale; MIS: Magical Ideation Scale; BAI: Beck Anxiety Inventory; BDI-II: Beck Depression Inventory-II.
Table 5
Predictive Performance for Clinical and Demographic Features.
| FEATURE | N | AUC | ACCURACY | PRECISION | RECALL | F1 | CHANGE |
|---|---|---|---|---|---|---|---|
| Baseline EEG | 20 | 0.47 | 0.45 | 0.45 | 0.45 | 0.45 | Baseline |
| DOCS Total | 20 | 0.97 | 0.85 | 0.89 | 0.80 | 0.84 | Improved |
| MIS Score | 18 | 0.62 | 0.67 | 0.71 | 0.56 | 0.63 | Improved |
| BAI Total | 20 | 0.94 | 0.90 | 0.90 | 0.90 | 0.90 | Improved |
| BDI-II Total | 20 | 0.90 | 0.90 | 1.00 | 0.80 | 0.89 | Improved |
| Age | 19 | 0.28 | 0.37 | 0.36 | 0.44 | 0.40 | Worse |
| Sex | 20 | 0.18 | 0.35 | 0.39 | 0.50 | 0.44 | Worse |
| Education | 20 | 0.38 | 0.45 | 0.43 | 0.30 | 0.353 | Worse |
[i] Note: Baseline metrics include only the support vector machine’s subject-level EEG scores in the second stage. N = number of subjects remaining after handling missing values. DOCS: Dimensional Obsessive-Compulsive Scale; MIS: Magical Ideation Scale; BAI: Beck Anxiety Inventory; BDI-II: Beck Depression Inventory-II.