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Reinforcement Learning and Decision Making in Depression in Adolescents and Young Adults: Insights from a New Model of the Probabilistic Reward Task Cover

Reinforcement Learning and Decision Making in Depression in Adolescents and Young Adults: Insights from a New Model of the Probabilistic Reward Task

Open Access
|Dec 2025

Figures & Tables

Table 1

Demographics and clinical characteristics of the sample.

M (SD)
N = 726
n (%)
Gender
    Cisgender female476 (66%)
    Cisgender male225 (31%)
    Non-binary, transgender, gender-fluid, or not reported23 (3.2%)
Ethnicity
    Hispanic or Latino/Latinx/Latine122 (17%)
    Non-Hispanic and non-Latino/Latinx/Latine602 (83%)
    Not reported2 (0.28%)
Race
    African American20 (2.8%)
    American Indian/Alaskan native2 (0.3%)
    Asian125 (18%)
    Native Hawaiian/other Pacific Islander1 (0.1%)
    White432 (62%)
    More than one race56 (8.1%)
    Other or not reported62 (8.9%)
Age19 (2)
Mood Symptoms
    MASQ-LOI16.71 (6.79)
N = 422
n (%)
Current Mood Diagnoses
    (Unipolar) Depressive Disorder121 (29%)
        Major depressive disorder73 (17%)
        Persistent depressive disorder48 (11%)
    Bipolar Disorder26 (6.2%)
        Bipolar I disorder11 (2.6%)
        Bipolar II disorder10 (2.4%)
        Bipolar disorder not otherwise specified5 (1.2%))
    Non-Psychiatric Control275 (65%)

[i] Notes: MASQ-LOI = Mood and Anxiety Symptom Questionnaire, Loss of Interest Anhedonia subscale.

cpsy-9-1-147-g1.png
Figure 1

Probabilistic Reward Task and Graphical Illustration of Action-DDM. (A) On each trial, participants saw a face with a long or short mouth and responded by pressing a button to indicate which mouth length was shown. Rewards were delivered three times more often for correct identifications of the rich vs. lean stimulus; assignment of short/long mouths to the rich/lean conditions was counterbalanced. (B) Graphical illustration of Action-DDM. Shaded nodes represent observed data and unshaded nodes represent parameter estimations. Double-bordered nodes represent trial-wise computed variables. Parameters include alpha: learning rate; Bv: the degree to which value differences influenced drift rate; Bz: the degree to which value differences influenced starting point bias; vintercept: baseline stimulus processing efficiency or drift rate; t: non-decision time; a: decision threshold.

Table 2

Summary of PRT performance statistics.

VARIABLEMEANSD
Block 1response bias0.050.21
discriminability0.670.27
rich acc0.820.10
lean acc0.790.12
rich RT529.6491.94
lean RT530.0092.43
rich correct RT530.6789.50
lean correct RT529.1489.91
rich error RT540.25143.50
lean error RT555.30144.90
Block 2response bias0.080.23
discriminability0.640.27
rich acc0.820.11
lean acc0.760.14
rich RT532.8894.20
lean RT541.1595.56
rich correct RT532.6291.94
lean correct RT543.7593.81
rich error RT550.44140.57
lean error RT554.92135.46
Averageresponse bias0.070.19
discriminability0.660.25
rich acc0.820.09
lean acc0.770.12
rich RT531.2688.70
lean RT535.5788.98
rich correct RT531.6586.19
lean correct RT536.4586.99
rich error RT544.77128.20
lean error RT554.31128.11
cpsy-9-1-147-g2.png
Figure 2

Posterior Predictive Performance. (A) Observed and simulated overall accuracy by stimulus type and response time (fast RT < .1 RT quantile; slow RTs > .9 RT quantile). (B) Observed and simulated changes in response bias and discriminability. The task trials were binned into eight timepoints with 25 trials each and response bias and discriminability were calculated independently for each timepoint. (C) Observed and simulated changes in response time distributions across four timepoints with 50 trials each. For a stimulus (rich or lean), we plotted the RT distributions when participants responded correctly (positively-valued RTs) and incorrectly (flipped to be negatively-valued RTs for illustrations).

cpsy-9-1-147-g3.png
Figure 3

Comparisons of PRT behavioral parameters between non-psychiatric control group (NC) and unipolar depression group (UNI).

Note: PRT summary statistics and Action-DDM parameters are indicated in gold and red respectively.

cpsy-9-1-147-g4.png
Figure 4

Correlations between anhedonic symptoms and PRT parameters.

Note: PRT summary statistics and Action-DDM parameters are indicated in gold and red respectively.

DOI: https://doi.org/10.5334/cpsy.147 | Journal eISSN: 2379-6227
Language: English
Submitted on: Apr 19, 2025
|
Accepted on: Nov 24, 2025
|
Published on: Dec 30, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Ziwei Cheng, Amelia D. Moser, Jenna Jones, Christopher D. Schneck, David J. Miklowitz, Daniel G. Dillon, Roselinde H. Kaiser, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.