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Global, Regional, and National Burden Attributed to Particulate Matter Pollution, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021 Cover

Global, Regional, and National Burden Attributed to Particulate Matter Pollution, 1990–2021: A Systematic Analysis for the Global Burden of Disease Study 2021

Open Access
|Feb 2026

Figures & Tables

Table 1

Global deaths and DALYs attributable to particulate matter pollution in 2021 and estimated annual percentage changes from 1990 to 2021.

CAUSE OF DEATH OR DALYSDEATHSDALYS
NUMBER OF CASES, 2021AGE‑STANDARDIZED RATES PER 100,000 PEOPLE, 2021AGE‑STANDARDIZED PAF (%), 2021EAPC IN AGE‑STANDARDIZED RATES (%), 1990–2021NUMBER OF CASES, 2021AGE‑STANDARDIZED RATES PER 100,000 PEOPLE, 2021AGE‑STANDARDIZED PAF (%), 2021EAPC IN AGE‑STANDARDIZED RATES (%), 1990–2021
All causes7,833,220.92 (6,479,473.76 to 9,263,395.35)96.69 (79.91 to 114.40)11.57 (9.73 to 13.53)−2.18 (−2.31 to −2.04)231,511,232.94 (194,538,892.20 to 270,855,451.37)2984.47 (2489.63 to 3487.35)8.25 (6.85 to 9.69)−2.27 (−2.39 to −2.15)
 APMP‑attributable causes4,718,812.24 (3,480,471.83 to 5,795,946.44)57.62 (42.32 to 70.99)6.90 (5.13 to 8.41)−0.34 (−0.48 to −0.20)120,004,672.01 (86,560,331.22 to 149,810,185.34)1483.61 (1069.48 to 1869.55)4.10 (2.98 to 5.13)−0.28 (−0.43 to −0.12)
 HPMP‑attributable causes3,112,926.41 (1,895,168.20 to 5,188,696.63)39.05 (23.97 to 64.45)4.67 (2.86 to 7.63)−3.81 (−4.13 to −3.49)111,462,958.29 (75,085,852.45 to 163,710,710.53)1500.29 (1028.38 to 2195.56)4.15 (2.79 to 5.97)−3.52 (−3.77 to −3.27)
 Female3,478,614.32 (2,842,903.78 to 4,127,413.84)78.35 (64.30 to 92.70)11.51 (9.52 to 13.43)−2.35 (−2.47 to −2.23)99,047,039.32 (82,679,826.81 to 117,756,358.69)2480.23 (2059.40 to 2951.19)7.60 (6.20 to 9.00)−2.43 (−2.54 to −2.31)
 Male4,354,606.60 (3,629,597.41 to 5,195,553.86)119.23 (99.30 to 142.09)11.70 (9.83 to 13.72)−2.06 (−2.21 to −1.90)132,464,193.62 (110,995,515.82 to 154,576,904.15)3535.80 (2953.30 to 4130.72)8.83 (7.39 to 10.23)−2.16 (−2.28 to −2.03)
Cardiovascular diseases4,482,496.23 (3,567,564.40 to 5,392,617.34)53.62 (42.70 to 64.57)22.80 (18.84 to 26.90)−1.92 (−2.06 to −1.78)99,637,837.09 (80,843,498.77 to 118,292,884.66)1161.77 (939.61 to 1380.37)22.98 (19.09 to 26.85)−1.90 (−2.03 to −1.76)
 Ischemic heart disease2,492,809.91 (1,866,677.65 to 3,103,230.08)29.88 (22.33 to 37.22)27.48 (21.21 to 33.85)−1.37 (−1.47 to −1.28)54,675,670.12 (41,652,489.01 to 67,418,885.61)638.48 (486.47 to 787.82)28.86 (22.37 to 35.37)−1.31 (−1.41 to −1.22)
 Stroke1,989,686.32 (1,530,479.07 to 2,493,237.87)23.74 (18.26 to 29.80)27.15 (21.64 to 33.64)−2.51 (−2.72 to −2.30)44,962,166.97 (35,020,338.76 to 55,467,023.53)523.30 (407.96 to 645.58)27.75 (22.32 to 34.22)−2.49 (−2.68 to −2.30)
 Intracerebral hemorrhage995,650.44 (763,171.63 to 1,249,510.29)11.69 (8.94 to 14.69)29.91 (23.60 to 36.66)−2.54 (−2.82 to −2.26)24,015,341.78 (18,414,608.05 to 29,838,879.10)276.93 (212.21 to 344.36)29.98 (23.83 to 36.70)−2.58 (−2.83 to −2.33)
 Ischemic stroke905,602.35 (694,785.38 to 1,144,793.07)11.01 (8.44 to 13.96)24.93 (19.93 to 31.10)−2.19 (−2.37 to −2.02)18,295,352.08 (14,324,970.64 to 22,541,397.17)215.64 (168.84 to 266.03)25.76 (20.60 to 32.03)−2.04 (−2.20 to −1.87)
 Subarachnoid hemorrhage88,433.52 (65,255.07 to 116,468.07)1.04 (0.76 to 1.36)24.73 (19.35 to 30.95)−4.64 (−4.92 to −4.35)2,651,473.11 (1,994,097.80 to 3,505,548.54)30.73 (23.13 to 40.64)24.50 (19.35 to 30.48)−4.20 (−4.43 to −3.97)
Maternal and neonatal disorders496,966.05 (419,486.39 to 580,880.21)8.03 (6.78 to 9.39)25.13 (23.34 to 27.04)−1.53 (−1.63 to −1.43)44,737,310.78 (37,766,689.50 to 52,293,054.19)723.06 (610.39 to 845.18)23.35 (21.54 to 25.21)−1.53 (−1.63 to −1.43)
 Neonatal disorders496,966.05 (419,486.39 to 580,880.21)8.03 (6.78 to 9.39)27.18 (25.28 to 29.26)−1.53 (−1.63 to −1.43)44,737,310.78 (37,766,689.50 to 52,293,054.19)723.06 (610.39 to 845.18)24.58 (22.65 to 26.55)−1.53 (−1.63 to −1.43)
 Neonatal preterm birth227,615.56 (189,160.11 to 271,466.91)3.68 (3.06 to 4.39)30.84 (28.69 to 33.10)−1.73 (−1.80 to −1.66)20,494,977.58 (17,038,342.06 to 24,435,506.76)331.25 (275.38 to 394.95)26.41 (24.31 to 28.80)−1.73 (−1.80 to −1.66)
 Neonatal encephalopathy due to birth asphyxia and trauma155,361.31 (129,104.49 to 187,255.72)2.51 (2.09 to 3.03)25.77 (23.38 to 28.09)−1.15 (−1.32 to −0.98)13,980,138.89 (11,617,949.83 to 16,850,172.87)225.97 (187.79 to 272.36)24.24 (21.91 to 26.44)−1.15 (−1.32 to −0.98)
 Neonatal sepsis and other neonatal infections54,025.69 (45,371.42 to 64,084.44)0.87 (0.73 to 1.04)23.24 (21.62 to 24.81)−0.96 (−1.09 to −0.84)4,861,948.25 (4,083,310.36 to 5,767,175.69)78.57 (65.98 to 93.19)21.20 (19.59 to 22.79)−0.96 (−1.09 to −0.84)
 Other neonatal disorders52,435.68 (36,764.50 to 65,587.59)0.85 (0.59 to 1.06)23.65 (21.45 to 25.59)−1.77 (−1.94 to −1.61)4,720,040.50 (3,309,887.35 to 5,902,580.05)76.29 (53.49 to 95.40)23.34 (21.15 to 25.30)−1.77 (−1.93 to −1.61)
 Hemolytic disease and other neonatal jaundice7527.82 (5818.67 to 9920.66)0.12 (0.09 to 0.16)22.40 (20.29 to 24.79)−3.52 (−3.69 to −3.35)680,205.56 (526,741.16 to 895,348.64)10.99 (8.51 to 14.47)18.82 (16.78 to 20.90)−3.51 (−3.68 to −3.34)
Respiratory infections and tuberculosis65,1356.39 (12,1714.90 to 1,076,711.75)8.68 (1.71 to 14.39)6.34 (1.26 to 10.44)−3.02 (−3.19 to −2.86)29,110,366.69 (7,007,734.71 to 48,141,777.96)420.28 (106.66 to 693.37)9.63 (2.44 to 15.57)−3.76 (−3.96 to −3.55)
 Lower respiratory infections651,238.01 (121,605.08 to 1,076,503.21)8.68 (1.71 to 14.39)30.21 (6.15 to 48.36)−3.02 (−3.19 to −2.86)29,098,330.84 (6,988,264.72 to 48,127,683.27)420.09 (106.35 to 693.12)35.84 (9.29 to 56.41)−3.76 (−3.96 to −3.55)
 Upper respiratory infections116.58 (18.26 to 299.46)0.00 (0.00 to 0.00)0.59 (0.28 to 0.85)−2.44 (−2.52 to −2.37)11,708.46 (2800.50 to 28,081.79)0.19 (0.05 to 0.45)0.23 (0.07 to 0.49)−2.32 (−2.39 to −2.25)
 Otitis media1.80 (0.55 to 4.62)0.00 (0.00 to 0.00)0.41 (0.24 to 0.74)−6.28 (−6.51 to −6.05)327.40 (156.27 to 626.36)0.01 (0.00 to 0.01)0.02 (0.01 to 0.03)−4.54 (−4.80 to −4.28)
Chronic respiratory diseases1,535,298.01 (1,214,704.19 to 1,918,255.85)18.51 (14.64 to 23.13)34.57 (28.32 to 42.55)−2.96 (−3.13 to −2.79)332,38712.44 (26,680,066.05 to 41,336,741.04)389.50 (312.59 to 484.62)30.10 (24.54 to 36.88)−2.87 (−3.01 to −2.74)
 Chronic obstructive pulmonary disease1,535,298.01 (1,214,704.19 to 1,918,255.85)18.51 (14.64 to 23.13)40.95 (33.37 to 50.00)−2.96 (−3.13 to −2.79)33,238,712.44 (26,680,066.05 to 41,336,741.04)389.50 (312.59 to 484.62)41.41 (34.01 to 50.17)−2.87 (−3.01 to −2.74)
Diabetes and kidney diseases281,908.84 (165,678.17 to 395,527.82)3.32 (1.95 to 4.66)8.69 (5.35 to 12.41)0.03 (−0.05 to 0.10)12,904,493.55 (7,501,414.23 to 19,485,253.91)148.92 (86.50 to 224.91)10.25 (6.18 to 14.71)0.77 (0.71 to 0.83)
 Diabetes mellitus281,908.84 (165,678.17 to 395,527.82)3.32 (1.95 to 4.66)16.94 (10.38 to 24.09)0.03 (−0.05 to 0.10)12,904,493.55 (7,501,414.23 to 19,485,253.91)148.92 (86.50 to 224.91)16.24 (9.94 to 23.12)0.77 (0.71 to 0.83)
 Diabetes mellitus type 2281,908.84 (165,678.17 to 395,527.82)3.32 (1.95 to 4.66)17.47 (10.69 to 24.84)0.03 (−0.05 to 0.10)12,904,493.55 (7,501,414.23 to 19,485,253.91)148.92 (86.50 to 224.91)17.07 (10.48 to 24.30)0.77 (0.71 to 0.83)
Neoplasms374,212.72 (236,358.33 to 520,255.39)4.34 (2.74 to 6.04)3.73 (2.42 to 5.17)−1.32 (−1.49 to −1.16)8,934,120.30 (5,681,090.30 to 12,409,780.48)102.08 (64.89 to 141.62)3.45 (2.24 to 4.78)−1.64 (−1.80 to −1.48)
 Tracheal, bronchus, and lung cancer374,212.72 (236,358.33 to 520,255.39)4.34 (2.74 to 6.04)18.47 (11.87 to 25.52)−1.32 (−1.49 to −1.16)8,934,120.30 (5,681,090.30 to 12,409,780.48)102.08 (64.89 to 141.62)19.15 (12.35 to 26.33)−1.64 (−1.80 to −1.48)
Sense organ diseasesNANANANA1,956,323.97 (−612,092.84 to 4,033,705.23)22.84 (−7.15 to 47.05)2.54 (−0.60 to 5.17)−1.51 (−1.72 to −1.29)
 Blindness and vision lossNANANANA1,956,323.97 (−612,092.84 to 4,033,705.23)22.84 (−7.15 to 47.05)6.83 (−1.66 to 14.11)−1.51 (−1.72 to −1.29)
 CataractNANANANA1,956,323.97 (−612,092.84 to 4,033,705.23)22.84 (−7.15 to 47.05)29.81 (−7.97 to 57.77)−1.51 (−1.72 to −1.29)
Enteric infections6558.80 (4931.11 to 9244.79)0.11 (0.08 to 0.15)0.60 (0.41 to 0.85)−6.20 (−6.49 to −5.92)593,959.88 (446,774.05 to 835,347.37)9.60 (7.22 to 13.50)0.94 (0.73 to 1.26)−6.19 (−6.47 to −5.91)
 Diarrheal diseases6558.80 (4931.11 to 9244.79)0.11 (0.08 to 0.15)0.70 (0.46 to 1.02)−6.20 (−6.49 to −5.92)593,959.88 (446,774.05 to 835,347.37)9.60 (7.22 to 13.50)1.15 (0.88 to 1.49)−6.19 (−6.47 to −5.91)
Other infectious diseases3715.75 (2867.22 to 4849.19)0.06 (0.05 to 0.08)0.74 (0.59 to 0.97)−2.65 (−3.03 to −2.26)334,394.98 (258,055.71 to 436,365.86)5.40 (4.17 to 7.05)0.91 (0.73 to 1.21)−2.65 (−3.03 to −2.26)
 Meningitis3434.16 (2619.15 to 4550.79)0.06 (0.04 to 0.07)1.89 (1.59 to 2.38)−2.70 (−3.11 to −2.29)309,052.23 (235,708.82 to 409,534.00)4.99 (3.81 to 6.62)2.40 (2.01 to 3.03)−2.70 (−3.11 to −2.29)
 Encephalitis281.58 (211.51 to 363.29)0.00 (0.00 to 0.01)0.38 (0.31 to 0.46)−1.85 (−2.03 to −1.68)25,342.75 (19,039.85 to 32,694.56)0.41 (0.31 to 0.53)0.61 (0.51 to 0.72)−1.85 (−2.03 to −1.68)
Other non‑communicable diseases708.14 (371.35 to 1049.21)0.01 (0.01 to 0.02)0.07 (0.04 to 0.10)−3.69 (−3.96 to −3.42)63,713.25 (33,411.31 to 94,401.21)1.03 (0.54 to 1.52)0.05 (0.03 to 0.08)−3.69 (−3.96 to −3.42)
 Sudden infant death syndrome708.14 (371.35 to 1049.21)0.01 (0.01 to 0.02)2.32 (1.84 to 2.83)−3.69 (−3.96 to −3.42)63,713.25 (33,411.31 to 94,401.21)1.03 (0.54 to 1.52)2.33 (1.84 to 2.83)−3.69 (−3.96 to −3.42)

Abbreviations: DALYs, disability‑adjusted life years. PMP, particulate matter pollution. APMP, ambient particulate matter pollution. HPMP, household particulate matter pollution. EAPCs, estimated annual percentage changes. PAFs, population attributable fractions.

aogh-92-1-4965-g1.png
Figure 1

Age‑specific numbers and rates of deaths and DALYs attributable to particulate matter pollution by sex in 2021.

(A) Deaths attributable to particulate matter pollution. (B) DALYs attributable to particulate matter pollution. DALYs, disability‑adjusted life years.

aogh-92-1-4965-g2.png
Figure 2

Age‑standardized DALY rates and their EAPCs attributable to ambient particulate matter pollution by country.

(A) Age‑standardised DALY rates, in 2021. (B) EAPCs in age‑standardised DALY rates, 1990–2021. DALYs, disability‑adjusted life years. EAPCs, estimated annual percentage changes.

aogh-92-1-4965-g3.png
Figure 3

Estimated annual percentage changes in age‑standardized DALY rates attributable to ambient particulate matter pollution, 1990–2021, for the leading ten level 3 attributable causes in 2021, by SDI quintile and GBD region.

For each region and SDI quintile, level 3 causes are ranked by attributable DALY counts in 2021 from left (first) to right (tenth). Causes are colored by their estimated annual percentage changes in age‑standardised DALY rates attributable to ambient particulate matter pollution, from 1990 to 2021. DALYs, disability‑adjusted life years. SDI, socio‑demographic index. GBD, Global Burden of Diseases, Injuries, and Risk Factors Study.

aogh-92-1-4965-g4.png
Figure 4

Global rankings of fractions of level 3 causes in age‑standardized DALYs attributable to ambient and household particulate matter pollution globally in 2021.

The list of causes of disease burden represents the level 3 causes of age‑standardised DALYs (per 100,000 population) attributable to APMP and HPMP observed for both sexes globally in 2021. This same list of health conditions was ranked according to their PAFs for both APMP and HPMP globally in 2021. The colors of the bars denote whether the PAFs are higher for females (yellow) or males (purple) as established by whether the 95% uncertainty interval of the absolute difference in PAFs includes zero. DALYs, disability‑adjusted life years. APMP, ambient particulate matter pollution. HPMP, household particulate matter pollution. PAFs, population attributable fractions.

aogh-92-1-4965-g5.png
Figure 5

Fraction of neonatal disorders, ischemic heart disease, and stroke in age‑standardized DALYs attributable to particulate matter pollution by region and by age group for females and males in 2021.

(A) By region. (B) By age group. The three leading GBD level 3 causes of particulate matter pollution‑attributable DALYs are shown. DALYs, disability‑adjusted life years. GBD, Global Burden of Disease Study.

aogh-92-1-4965-g6.png
Figure 6

Age‑standardized death and DALY rates attributable to particulate matter pollution across 21 GBD regions by socio‑demographic index, 1990–2021.

(A) Age‑standardised death and DALY rates attributable to particulate matter pollution by SDI. (B) Age‑standardised death and DALY rates attributable to household particulate matter pollution by SDI. (C) Age‑standardised death and DALY rates attributable to ambient particulate matter pollution by SDI. For each region, points from left to right depict estimates from each year from 1990 to 2021. DALYs, disability‑adjusted life years. GBD, Global Burden of Diseases, Injuries, and Risk Factors Study. SDI, socio‑demographic index.

DOI: https://doi.org/10.5334/aogh.4965 | Journal eISSN: 2214-9996
Language: English
Submitted on: Sep 12, 2025
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Accepted on: Jan 31, 2026
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Published on: Feb 24, 2026
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2026 YangYang Li, Ping Sun, Yiheng Yin, Chang Yu, Dongjie Xie, Zhengwei Wan, Bolin Deng, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.