Fig 1.

Fig. 2.

Baseline age and anthropometric characteristics
| Variable | HIIT group | MICT group | p-value |
|---|---|---|---|
| Age [years] | 42.13 ± 6.81 | 41.10 ± 2.92 | 0.700 |
| Height [cm] | 157.25 ± 2.19 | 157.70 ± 2.06 | 0.659 |
| Body weight [kg] | 81.77 ± 12.10 | 87.58 ± 6.49 | 0.209 |
| BMI [kg/m2] | 33.08 ± 4.95 | 35.22 ± 2.58 | 0.255 |
Description of the exercise interventions
| HIIT [15] | MICT | |
|---|---|---|
| Frequency | Three days per week | Three days per week |
| Intensity |
|
|
| Time or Duration |
| The session lasted 45 minutes (5–10 minutes of warming up, 30 minutes of the working phase, and 3–5 minutes of cooling down) |
| Type/mode | Treadmill, interval walking exercise | Treadmill, continuous walking exercise |
Results of the two groups at baseline and post-intervention
| Variables | HIIT group | MICT group | Levene's test | Unpaired t-test | |
|---|---|---|---|---|---|
| p-value | p-value | ||||
| PAI-1 [ng/mL] | baseline | 37.42 ± 3.52 | 38.49 ± 2.40 | 0.089 | 0.457 |
| post | 29.09 ± 2.67 | 30.37 ± 2.92 | 0.995 | 0.352 | |
| p-value | < 0.001* | < 0.001* | |||
| HbA1c[%] | baseline | 8.34 ± 0.44 | 8.15 ± 0.63 | 0.297 | 0.482 |
| post | 6.45 ± 0.50 | 6.78 ± 0.36 | 0.377 | 0.127 | |
| p-value | < 0.001* | < 0.001* | |||
| BMI [kg/m2] | baseline | 33.08 ± 4.95 | 35.22 ± 2.58 | 0.079 | 0.255 |
| post | 32.97 ± 4.29 | 34.76 ± 3.00 | 0.289 | 0.314 | |
| p-value | 0.783 | 0.239 | |||