Treatment of bipolar mania with obsessive symptoms with clozapine: a case report
Abstract
Obsessive compulsive disorder (OCD) and bipolar disorder can be comorbid, although the exact pathogenesis of obsessive compulsive symptoms (OCS) in bipolar disorder is not clear. Bipolar disorder and OCD can co-occur either due to independent aetiologies or due to the hyposerotonergic state caused by treatment with atypical antipsychotics leading to emergence of OCS. Clozapine, an atypical antipsychotic has been repeatedly implicated in de novo emergence or exacerbation of OCS. In this case report, we describe an elderly man with bipolar disorder currently manic and OCS who was successfully treated with clozapine.
DOI: http://dx.doi.org/10.4038/sljpsyc.v4i2.5311
© 2013 Shubhangi Parkar, Chetali Dhuri, Rueeta Athalye, published by Sri Lanka College of Psychiatrists
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