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Successful Management of Acyclovir-Induced Nephrotoxicity in a Patient with Varicella Zoster Virus Encephalitis in a Resource-Limited Setting- A Case Report Cover

Successful Management of Acyclovir-Induced Nephrotoxicity in a Patient with Varicella Zoster Virus Encephalitis in a Resource-Limited Setting- A Case Report

Open Access
|Jun 2025

Abstract

This case report describes a 42-year-old male patient who developed acyclovir-induced nephrotoxicity while being treated for varicella zoster virus encephalitis. The case report underscores the challenges faced in a low-income setting where continuing acyclovir at a reduced dose was necessary due to the lack of alternative antiviral treatments. The patient's condition was successfully managed through careful dose adjustment and intensive monitoring, resulting in a gradual recovery of renal function.

DOI: https://doi.org/10.4038/joth.v1i2.8 | Journal eISSN: 3084-9314
Language: English
Page range: 98 - 103
Published on: Jun 30, 2025
Published by: Rajarata University of Sri Lanka
In partnership with: Paradigm Publishing Services

© 2025 Supun Wedasingha, Rathnasiri Rajapaksha, Thilina Rathnasekara, Hemal Senanayake, Chamara Sarathchandra, published by Rajarata University of Sri Lanka
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.