Duodenal Neuroendocrine Tumour: An Incidental Discovery of an Indolent Disease

Neuroendocrine neoplasms arise from the neuroendocrine cells distributed throughout the body. Duodenal neuroendocrine neoplasms are rare. Most of these are nonfunctional and therefore present with nonspecific symptoms or with clinico-pathological features unique to their location. The management of neuroendocrine tumours is dependent on its grade and stage. Classification of neuroendocrine tumours and hence its grading has been updated multiple times. Here we present a patient who complained of very non specific upper gastrointestinal symptoms and was found to have a duodenal polyp on endoscopy which was diagnosed by histology and immunohistochemistry as a grade three neuroendocrine tumour according to the latest WHO classification (2022).