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The Oncological Safety of Submental Flap Reconstruction in Head-and-Neck Cancers: An Extended Follow-up Study Cover

The Oncological Safety of Submental Flap Reconstruction in Head-and-Neck Cancers: An Extended Follow-up Study

Open Access
|Aug 2024

Figures & Tables

Figure 1:

Survival difference between level I positive versus level I negative patients (P = 0.27)
Survival difference between level I positive versus level I negative patients (P = 0.27)

Figure 2:

Survival difference between clear versus close/positive tumor margins P = 0.47
Survival difference between clear versus close/positive tumor margins P = 0.47

Breakdown of cervical lymph node involvement (n=88)

Positive cervical lymph node (involvement by levels)Number of subjects (percentage)
No lymph node involved66 (75.0)
Ipsilateral positive level I11 (12.5)
Ipsilateral positive levels I and II2 (2.3)
Ipsilateral positive level I and III1 (1.1)
Bilateral positive level I1 (1.1)
Ipsilateral positive level II7 (8.0)

Details of subjects with primary local recurrence (n=26)

Total patients with recurrenceNumber of patients (percentage)
Involved margins7 (26.9)
Close margins5 (19.2)
Level I positive lymph node5 (19.2)
Involved/close margins and level I positive lymph node5 (19.2)
Clear margins and level I (pN0)4 (15.3)

Characteristics of demographics and clinical data (n=88)

VariableNumber of sub-jects (percentage)
Gender
  Male71 (80.68)
  Female17 (19.31)
Median age55.3 (25–79) years
Mean follow-up months33.5 (4–75) months
Risk factors: (Smoking, chewable tobacco, betel nut, alcohol)
  Yes59 (67.04)
  No29 (32.95)
Primary site
  Buccal mucosa37 (42.05)
  Tongue24 (27.27)
  Lower alveolus27 (30.68)
pTNM stage:
  No primary tumor (salvage surgery post-induction chemotherapy)3 (3.40)
  Stage I14 (15.90)
  Stage II27 (30.68)
  Stage III18 (20.45)
  Stage IV26 (29.54)
Flap complications
  Complete loss3 (3.40)
  Partial loss/salvaged17 (19.31)
  Uneventful recovery68 (77.27)

Summary of pattern of recurrence (n=88)

RecurrenceNumber of subjects (percentage)
No recurrence51 (58.0)
Local recurrence10 (11.4)
Local recurrence away from flap10 (11.4)
Local and nodal recurrence6 (6.8)
Nodal recurrence9 (10.2)
Distant metastasis1 (1.1)
Lost to follow-up1 (1.1)
Language: English
Page range: 1 - 7
Submitted on: Aug 10, 2023
Accepted on: Jul 6, 2024
Published on: Aug 16, 2024
Published by: Shakuat Khanum Memorial Cancer Hospital and Research Centre
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2024 Muhammad Umar Qayyum, Ahmed Ali Keerio, Ramsha Zaheer, Usman Mushtaq, Verda Baig, Raza Hussain, Muhammad Faisal, published by Shakuat Khanum Memorial Cancer Hospital and Research Centre
This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.