Figure 1.
PICU patients treated with nitroglycerin – demographic and comorbidity data_
| No. | Year of admission | Sex | Age, days | Reason for PICU admission | IMV, days | Inotropic support, days | Renal replacement therapy | Sepsis | Length of stay, days |
|---|---|---|---|---|---|---|---|---|---|
| 1. | 2022 | M | 315 (10.5 months) | Postoperative care (cardiac surgery) | 17 | 7 | NN | + | † |
| 2. | 2022 | M | 505 (16.8 months) | Postoperative care (cardiac surgery) | 33 | 43 | HDF + peritoneal dialysis | + | 41 |
| 3. | 2023 | F | 73 (2.4 months) | Postoperative care (cardiac surgery) | 28 | 25 | NN | + | 62 |
| 4. | 2023 | F | 5692 (15,5years) | Acute liver failure | * | 4 | HDF | + | 109 |
| 5. | 2024 | M | 106 (3.5 months) | Postoperative care (craniosynostosis surgery) | 1 | - | No AKI | - | 3 |
| 6. | 2024 | M | 22 (0.7 months) | Congenital heart disease with cardiogenic shock | 53 | 23 | HDF | + | 63 |
| 7. | 2024 | F | 244 (8.1 months) | Bronchiolitis with ARDS | 18 | 6 | NN | + | 31 |
PICU patients treated with nitroglycerin – ALI location, management and outcome_
| No. | ALI etiology | ALI location | NG administration | NG started | Treatment duration, days | ACT | ACT, days | ABX | Maximum MetHb value, % | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| 1. | PH | Extremities of all four limbs (hands and feet) | NG patches of 5 mg every 48 hours | D6 | † | LMWH | † | + | 0.4 | Stopped ischemia progression (child died of non-ALI related complications) |
| 2. | AC | Right hand fingers | NG ointment 4 mg/g every 24 hours | D0 | 12 | NFH → LMWH | 28 | + | 1.2 | Stopped ischemia progression. Partial recovery, partial amputation of 4th finger |
| 3. | PH | Fingers of both feet | NG ointment 4 mg/g every 24 hours | D1 | 9 | LMWH | 28 | + | 1.6 | Full recovery |
| 4. | PH | Both legs, up to the knees | NG ointment 4 mg/g every 24 hours | D5 | 3 | NFH → LMWH | 89 | + | 1.9 | No recovery, early amputation due to infectious gangrene |
| 5. | AC | Right hand | NG ointment 4 mg/g every 12 hours | D1 | 2 | LMWH | 89 | - | 1.2 | Full recovery |
| 6. | AC | Left leg, up to the knee | NG ointment 4 mg/g every 12 hours | D0 | 17 | LMWH | 7 | + | 1.8 | Full recovery |
| 7. | AC | 1st to 4th right hand fingers | NG ointment 4 mg/g every 12 hours | D5 | 20 | NFH → LMWH | 79 | + | 1.4 | Stopped ischemia progression. Partial recovery, partial amputation of 1st finger |