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Pharmacoeconomic Analysis of Medicines Used for Bronchial Asthma in Children in Kazakhstan Cover

Pharmacoeconomic Analysis of Medicines Used for Bronchial Asthma in Children in Kazakhstan

Open Access
|May 2025

Figures & Tables

Calculation of CER coefficients for different severity levels of bronchial asthma_

SeverityTreatment tacticsThe cost of the course, USD (tenge)Effectiveness, %CER
MildScheme 1USD 5.4 (2380 tenge)700.077 (34)
Scheme 2USD 10.8 (4760 tenge)630.171 (75.5)
ModerateScheme 1USD 11.17 (4920 tenge)400.27 (123)
Scheme 2USD 19.61 (8640 tenge)560.35 (154.2)
SevereScheme 1USD 25.3 (11150 tenge)500.506 (223)
Scheme 2USD 47.88 (21100 tenge)600.798 (351.6)

Distribution of patients according to severity, age_

Degree of severityAgeNumber of people
MildFrom 6 to 8 years old10
From 9 to 12 years old8
MediumFrom 6 to 8 years old12
From 9 to 12 years old9
SevereFrom 6 to 8 years old10
From 9 to 12 years old5

Treatment regimens depending on the stage, age_

The stage of bronchial asthmaAgeMedicationCost USD (tenge)
The mild stage6–8 yearsBerodual inhalation solution 20 ml 1 flUSD 5.4 (2380 tenge)
9–12 yearsBerodual inhalation solution 20 ml 2 flUSD 10.8 (4760 tenge)
The medium stage6–8 yearsFlixotide 50 mcg 120 doses 1 fl + Salbutamol 100 mcg 200 doses 1 flUSD 11.17 (4920 tenge)
9–12 yearsFlixotide 50 mcg 120 doses 2 fl + Salbutamol 100 mcg 200 doses 1 flUSD 19.61 (8640 tenge)
The severe stage6–8 yearsSymbicort 80/4.5 mcg 120 doses of 1 fl. + Salbutamol 100 mcg 200 doses of 1 fl.USD 25.3 (11150 tenge)
9–12 yearsSymbicort 80/4.5 mcg 120 doses 2 fl. + Salbutamol 100 mcg 200 doses of 1 fl.USD 47.88 (21100 tenge)

The number of exacerbations, according to the treatment regimens in each group_

The stage of bronchial asthmaAge groupNumber of patientsTreatment regimenThe frequency of exacerbations per yearPercentage ratio
The mild stage6–8 years old10Scheme 1330%
9–12 years old8Scheme 2337%
The medium stage6–8 years old12Scheme 1660%
9–12 years old9Scheme 2444%
The severe stage6–8 years old10Scheme 1550%
9–12 years old5Scheme 2240%
DOI: https://doi.org/10.34763/jmotherandchild.20252901.d-24-00046 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 20 - 29
Submitted on: Nov 4, 2024
Accepted on: Feb 13, 2025
Published on: May 24, 2025
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Elmira Serikbayeva, Nizom Suyunov, Baurzhan Makhatov, Ainash Atimtaikyzy, Aigul Ibragimova, Maksuda Abdullaeva, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.