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Use of Fibrin Glue in the Treatment of Persistent Pneumothorax in Premature Infants at the Limit of Viability: Ethical Issues and Two and A Half Years Follow-Up Cover

Use of Fibrin Glue in the Treatment of Persistent Pneumothorax in Premature Infants at the Limit of Viability: Ethical Issues and Two and A Half Years Follow-Up

Open Access
|Nov 2023

Abstract

Introduction

Due to the extreme immaturity of many internal organs, including lungs, infants at the limit of viability are more predisposed to a pneumothorax (PTX). In some cases, PTX becomes persistent. Previously, only a few attempts of PTX treatment with fibrin glue were reported. However, its impact on further lung development is unknown.

Case report

We present a case of an extremely preterm infant with persistent PTX who was successfully treated with fibrin glue. In addition, we present a two-and-a-half-year corrected age follow-up focusing on respiratory problems, motor development and sensory organs. Furthermore, we touch upon the related ethical issues.

Conclusions

Fibrin glue should be used to treat persistent PTX even in an extremely preterm infant. No adverse effects were observed. At the two-and-a-half-year corrected age follow-up, despite severe bronchopulmonary dysplasia development, no serious pulmonary problems were observed. However, the child's development is uncertain. This situation raises important ethical issues concerning saving the lives of infants at the limit of viability.

DOI: https://doi.org/10.34763/jmotherandchild.20232701.d-23-00061 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 190 - 197
Submitted on: Jul 5, 2023
Accepted on: Sep 15, 2023
Published on: Nov 22, 2023
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2023 Magdalena Rutkowska, Martyna Woynarowska, Iwona Terczyńska, Małgorzata Seroczyńska, Dariusz Mydlak, Jarosław Mądzik, Ewa Nowakowska, Katarzyna Niepokój, Sławomir Szczepaniak, Krystyna Polak, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.