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Umbilical cord arterial blood lactate dehydrogenase and pH as predictors of perinatal outcome in high-risk term pregnancies: A cohort study Cover

Umbilical cord arterial blood lactate dehydrogenase and pH as predictors of perinatal outcome in high-risk term pregnancies: A cohort study

By: Naina Kumar and  Ashu Yadav  
Open Access
|Jul 2022

References

  1. Jehan I, Harris H, Salat S, Zeb A, Mobeen N, Pasha O, et al. Neonatal mortality, risk factors and causes: a prospective population-based cohort study in urban Pakistan. Bull World Health Organ. 2009;87(2):130-8. doi: 10.2471/blt.08.050963.
  2. United Nations Inter-Agency Group for Child Mortality Estimation (UN IGME). Neonatal mortality. New York: United Nations Children’s Fund (UNICEF), 2021. Available from: https://data.unicef.org/topic/child-survival/neonatal-mortality/
  3. WHO. World Health Report, 2005. Make Every Mother and Child Count. Geneva, Switzerland: WHO, 2005; XXIII, 219 pp. ISBN 92 4 156290 0. Available from: http://www.who.int/whr/2004/annex/en/index.html.
  4. Lawn JE, Cousens S, Zupan J, Lancet Neonatal Survival Steering Team. 4 million neonatal deaths: when? Where? Why? Lancet. 2005;365(9462):891-900. doi: 10.1016/S0140-6736(05)71048-5.
  5. Lawn JE, Cousens SN, Wilczynska K. Estimating the causes of four million neonatal deaths in the year 2000: statistical annex. In: The world health report 2005. Geneva: WHO; 2005.
  6. WHO: World Health Statistics. Geneva: WHO, 2013. Available from: http://www.who.int/gho/publications/worldhealthstatistics/2013/en/.
  7. National Neonatal Perinatal Database : Human Reproduction Research Centre Network : Report 2002-2003. Compiled & Published by NNPD Nodal Center at Department of Pediatrics, WHO Collaborating Centre Newborn; Training & Research, All India Institute of Medical Sciences, New Delhi for National Neonatology Forum NNPD Network, India. New Delhi, India: Nodal Centre, AIIMS, 2006; 45 p. Available from: https://www.newbornwhocc.org/pdf/HRRC-Report_2002-03.pdf
  8. Cloherty JP, Eichenwald EC, Stark AR. Manual of neonatal care. 6th ed. Philadelphia : Wolters Kluwer Health/Lippincott Williams & Wilkins, c2008; p. 735-52. ISBN 9780781769846.
  9. Parer JT, Livingston EG. What is fetal distress? Am J Obstet Gynecol. 1990;162(6):14215; discussion 1425-7. doi: 10.1016/0002-9378(90)90901-i.
  10. WHO. Basic Newborn Resuscitation: A Practical Guide. Geneva: WHO; 1997. Available from: https://pubmed.ncbi.nlm.nih.gov/23700652/.
  11. American College of Obstetricians and Gynecologists. Task Force on Neonatal Encephalopathy and Cerebral Palsy.; American Academy of Pediatrics. Neonatal encephalopathy and cerebral palsy : defining the pathogenesis and pathophysiology. 1st edition. Washington, DC, USA: American College of Obstetricians and Gynecologists, ©2003; XIX, 94 p.
  12. Gibson PR, Dudley FJ. Ischemic hepatitis: clinical features, diagnosis and prognosis. Aust N Z J Med. 1984;14(6):822-5. doi: 10.1111/j.1445-5994.1984.tb03780.x.
  13. Choudhary M, Sharma D, Dabi D, Lamba M, Pandita A, Shastri S. Hepatic dysfunction in asphyxiated neonates: prospective case-controlled study. Clin Med Insights Pediatr. 2015;9:1-6. doi: 10.4137/CMPed.S21426.
  14. Reddy S, Dutta S, Narang A. Evaluation of lactate dehydrogenase, creatine kinase and hepatic enzymes for the retrospective diagnosis of perinatal asphyxia among sick neonates. Indian Pediatr. 2008;45(2):144-7.
  15. Karlsson M, Wiberg-Itzel E, Chakkarapani E, Blennow M, Winbladh B, Thoresen M. Lactate dehydrogenase predicts hypoxic ischaemic encephalopathy in newborn infants: a preliminary study. Acta Paediatr. 2010;99(8):1139-44. doi: 10.1111/j.1651-2227.2010.01802.x.
  16. Victory R, Penava D, Da Silva O, Natale R, Richardson B. Umbilical cord pH and base excess values in relation to adverse outcome events for infants delivering at term. Am J Obstet Gynecol. 2004;191(6):2021-8. doi: 10.1016/j.ajog.2004.04.026.
  17. Watt WF, Tan KH, Yeo GS. Umbilical cord lactate: A preliminary study of 130 term babies. Singapore J Obstet Gynecol. 2002;33(2):42-8.
  18. Ogik V, Muyingo M, Musooko M, Nankunda J. Umbilical artery lactate levels and associated maternal and newborn characteristics at Mulago National Referral Hospital: a cross-sectional observational study. BMJ Open. 2021;11(8):e043827. doi: 10.1136/bmjopen-2020-043827.
  19. Mohamed MA, Aly H. Impact of race on male predisposition to birth asphyxia. J Perinatol. 2014;34(6):449-52. doi: 10.1038/jp.2014.27.
  20. Mazouri A, Fallah R, Saboute M, Taherifard P, Dehghan M. The prognostic value of the level of lactate in umbilical cord blood in predicting complications of neonates with meconium aspiration syndrome. J Matern Fetal Neonatal Med. 2021;34(7):1013-9. doi: 10.1080/14767058.2019.1623195.
  21. Y RB, S LR, Lewis LE. Umbilical cord blood acid-base parameters and lactate as predictors of subsequent meconium aspiration syndrome in neonates. Indian J Pediatr. 2022 Feb 16. doi: 10.1007/s12098-022-04082-7. Epub ahead of print.
  22. Wiberg-Itzel E, Josephson H, Wiberg N, Olson L, Winbladh B, Karlsson M. Lactic dehydrogenase in umbilical cord blood in healthy infants after different modes of delivery. J Neonatal Biol. 2015;4:204. doi:10.4172/2167-0897.1000204.
  23. Gaertner VD, Bassler D, Zimmermann R, Fontijn JR. Reference values for umbilical artery lactate by mode of delivery and gestational age: a retrospective observational study. Neonatology. 2021;118(5):609-16. doi: 10.1159/000518748.
  24. Goyel S, Sen G, Sarkar D, Choudhury S, Bhattacharjee D, Saha S. Prospective study to evaluate correlation between umbilical cord blood pH at birth and perinatal outcome in relation to the mode of delivery. Int J Res Health Sci. 2014;2(3):792-9.
  25. Kamath MK, Asha MN, Saihari B, Sneha M. Lactate dehydrogenase as a prognosticating tool in predicting NICU stay and oxygen dependence in meconium stained amniotic fluid neonates. J Clin Diag Res. 2019;13(5):SC11-SC13. 10.7860/JCDR/2019/40139.12809.
  26. Khoshnow Q, Mongelli M. Cord Blood Lactate and pH Values at Term and Perinatal Outcome: A Retrospective Cohort Study. Webmed Central Obstetrics and Gynaecology. 2010;1(9):WMC00694.
  27. Misra S, Sarkar S, Das NK. Correlation of umbilical blood pH and outcome in meconium-stained deliveries. Asian J Med Sci. 2016;7(4):113-5. doi: 10.3126/ajms.v7i4.14211. Available from: https://www.nepjol.info/index.php/AJMS/article/view/14211.
  28. Patil SS, Sukanya, Rath S, George CE. Study on umbilical cord arterial blood gas analysis and cord blood lactate levels as predictors for adverse neonatal outcome: an observational study. Int J Reprod Contracept Obstet Gynecol. 2018;7(4):1494-500. doi: 10.18203/2320-1770.ijrcog20181342.
  29. Geetha Damodaran K, Gilsa Engoor S, Janaki M, Parvathy R. APGAR score and umbilical cord blood levels of lactate and creatinine in perinatal asphyxia. Int J Biomed Res. 2015;6(4):242-5. doi: 10.7439/IJBR.V6I4.1715.
  30. Meena P, Meena M, Gunawat M. Correlation of APGAR score and cord blood pH with severity of birth asphyxia and short-term outcome. Int J Contemp Pediatr. 2017;4(4):13258. 10.18203/2349-3291.ijcp20172659.
  31. Karlsson M, Dung KT, Thi TL, Borgström E, Jonstam K, Kasström L, et al. Lactate dehydrogenase as an indicator of severe illness in neonatal intensive care patients: a longitudinal cohort study. Acta Paediatr. 2012;101(12):1225-31. doi: 10.1111/apa.12014.
  32. Eltaieb E, Elkholy H. Umbilical cord arterial blood gas study and cord blood lactate predictability for unfavorable neonatal outcomes. Int Gyn & Women’s Health. 2018;1(2):104-10. doi: 10.32474/IGWHC.2018.01.000123.
  33. Jahan R, Khanam A, Masood A, Rehman R. Diagnostic accuracy of lactate dehydrogenase for diagnosis of perinatal asphyxia in neonates with non-reactive CTG. Pak J Med Health Sci (PJMHS). 2019;13(2):458-60.
  34. Antil PK, Mahajan K, Chandwani C, Rathee S, Bhardwaj AK, Maini B, et al. Serum lactate dehydrogenase levels with birth asphyxia in term neonates. Journal of Clinical and Diagnostic Research. 2020;14(2):SC01-SC03. doi: 10.7860/JCDR/2020/43249.13476.
  35. Malik M, Mital R, Jaiswal V, Malik NP, Agarwal V, Upadhyay A. Correlation of acidosis with blood markers (LDH and nucleated RBCs/100 WBC) and with mortality and neurodevelopmental outcome in neonates with perinatal asphyxia. Int J Contemp Med Res. 2016;3(4):938-42.
  36. Torres Yordán NC, Lewis AG, McElrath TF, Tolan NV, Greenberg JA. Point-of-care assessment of combined umbilical arterial and venous lactate: A potential screening test for neonatal acidosis. Int J Gynaecol Obstet. 2022;158(1):86-92. doi: 10.1002/ijgo.13968. Epub 2021 Oct 31.
  37. Allanson ER, Waqar T, White C, Tunçalp Ö, Dickinson JE. Umbilical lactate as a measure of acidosis and predictor of neonatal risk: a systematic review. BJOG. 2017;124(4):584594. doi: 10.1111/1471-0528.14306.
DOI: https://doi.org/10.34763/jmotherandchild.20222601.d-22-00004 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
Language: English
Page range: 27 - 34
Submitted on: Jan 6, 2022
Accepted on: Mar 29, 2022
Published on: Jul 20, 2022
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2022 Naina Kumar, Ashu Yadav, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.