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The retrospective molecular analysis of large or giant congenital melanocytic nevi in a group of Polish children Cover

The retrospective molecular analysis of large or giant congenital melanocytic nevi in a group of Polish children

Journal of Mother and Child
Volume 25 (2021): Issue 1 (March 2021)
By: Katarzyna Wertheim-Tysarowska,  Orest Szczygielski,  Katarzyna Seliga,  Andrzej Tysarowski,  Jerzy Bal,  Elżbieta Michalak,  Agnieszka Magdalena Rygiel and  Ewa Sawicka  
Open Access
|Oct 2021

References

  1. Nikfarjam J, Chambers E. Congenital melanocytic nevi and the risk of malignant melanoma: establishing a guideline for primary-care physicians. Einstein J Biol Med. 2011;27(2):59-66. doi: 10.23861/EJBM20112745.
    Open DOISearch in Google ScholarBack to article
  2. Shah J, Feintisch AM, Granick MS. Congenital melanocytic nevi. Eplasty. 2016 Jan 28;16:ic4.
    Search in Google ScholarBack to article
  3. del Carmen Boente M. Congenital melanocytic nevi. p. 249-60. In: Pediatric skin of color. Eds. Silverberg NB, Durán-McKinster C, Tay Y-K. New York: Springer-Verlag, 2015; XV, 473 p. ISBN 9781-4614-6653-6 (hardcover). ISBN 978-1-4614-6654-3 (eBook). doi: 10.1007/978-1-4614-6654-3.
    Open DOISearch in Google ScholarBack to article
  4. Price HN. Congenital melanocytic nevi: update in genetics and management. Curr Opin Pediatr. 2016;28(4):476-82. doi: 10.1097/MOP.0000000000000384.
    Open DOISearch in Google ScholarBack to article
  5. Kinsler VA, Thomas AC, Ishida M, Bulstrode NW, Loughlin S, Hing S, et al. Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS. J Invest Dermatol. 2013;133(9):2229-36. doi: 10.1038/jid.2013.70.
    Open DOISearch in Google ScholarBack to article
  6. Krengel S, Scope A, Dusza SW, Vonthein R, Marghoob AA. New recommendations for the categorization of cutaneous features of congenital melanocytic nevi. J Am Acad Dermatol. 2013;68(3):441-51. doi: 10.1016/j.jaad.2012.05.043.
    Open DOISearch in Google ScholarBack to article
  7. Polubothu S, McGuire N, Al-Olabi L, Baird W, Bulstrode N, Chalker J, et al. Does the gene matter? Genotype-phenotype and genotype-outcome associations in congenital melanocytic naevi. Br J Dermatol. 2020;182(2):434-43. doi: 10.1111/bjd.18106.
    Open DOISearch in Google ScholarBack to article
  8. Dessars B, De Raeve LE, Morandini R, Lefort A, El Housni H, Ghanem GE, et al. Genotypic and gene expression studies in congenital melanocytic nevi: insight into initial steps of melanotumorigenesis. J Invest Dermatol. 2009;129(1):139-47. doi: 10.1038/jid.2008.203.
    Open DOISearch in Google ScholarBack to article
  9. Bekiesińska-Figatowska M, Szczygielski O, Boczar M, Mądzik J, Klepacka T, Michalak E, et al. Neurocutaneous melanosis in children with giant congenital melanocytic nevi. Clin Imaging. 2014;38(2):79-84. doi: 10.1016/j.clinimag.2013.10.001.
    Open DOISearch in Google ScholarBack to article
  10. Sawicka E, Szczygielski O, Żak K, Pęczkowski P, Michalak E, Bekiesińska-Figatowska M. Giant congenital melanocytic nevi: selected aspects of diagnostics and treatment. Med Sci Monit. 2015 Jan 11;21:123-32. doi: 10.12659/MSM.891279.
    Open DOISearch in Google ScholarBack to article
  11. Roh MR, Eliades P, Gupta S, Tsao H. Genetics of melanocytic nevi. Pigment Cell Melanoma Res. 2015;28(6):661-72. doi: 10.1111/pcmr.12412.
    Open DOISearch in Google ScholarBack to article
  12. Ichii-Nakato N, Takata M, Takayanagi S, Takashima S, Lin J, Murata H, et al. High frequency of BRAFV600E mutation in acquired nevi and small congenital nevi, but low frequency of mutation in medium-sized congenital nevi. J Invest Dermatol. 2006;126(9):2111-8. doi: 10.1038/sj.jid.5700366.
    Open DOISearch in Google ScholarBack to article
  13. Charbel C, Fontaine RH, Malouf GG, Picard A, Kadlub N, El-Murr N, et al. NRAS mutation is the sole recurrent somatic mutation in large congenital melanocytic nevi. J Invest Dermatol. 2014;134(4):1067-74. doi: 10.1038/jid.2013.429.
    Open DOISearch in Google ScholarBack to article
  14. Stark MS. Large-giant congenital melanocytic nevi: moving beyond NRAS mutations. J Invest Dermatol. 2019;139(4):756-9. doi: 10.1016/j.jid.2018.10.003.
    Open DOISearch in Google ScholarBack to article
  15. Alqathama A. BRAF in malignant melanoma progression and metastasis: potentials and challenges. Am J Cancer Res. 2020;10(4):1103-14.
    Search in Google ScholarBack to article
  16. Frech M, Darden TA, Pedersen LG, Foley CK, Charifson PS, Anderson MW, Wittinghofer A. Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study. Biochemistry. 1994;33(11):3237-44. doi: 10.1021/bi00177a014.
    Open DOISearch in Google ScholarBack to article
  17. Hélias-Rodzewicz Z, Funck-Brentano E, Terrones N, Beauchet A, Zimmermann U, Marin C, et al. Variation of mutant allele frequency in NRAS Q61 mutated melanomas. BMC Dermatol. 2017;17(1):9. doi: 10.1186/s12895-017-0061-x.
    Open DOISearch in Google ScholarBack to article
  18. Bauer J, Curtin JA, Pinkel D, Bastian BC. Congenital melanocytic nevi frequently harbour NRAS mutations but no BRAF mutations. J Invest Dermatol. 2007;127(1):179-82. doi: 10.1038/sj.jid.5700490.
    Open DOISearch in Google ScholarBack to article
  19. Martins da Silva V, Martinez-Barrios E, Tell-Martí G, Dabad M, Carrera C, Aguilera P, et al. Genetic abnormalities in large to giant congenital nevi: beyond NRAS mutations. J Invest Dermatol. 2019;139(4):900-8. doi: 10.1016/j.jid. 2018.07.045.
    Open DOISearch in Google ScholarBack to article
  20. Pedersen M, Küsters-Vandevelde HVN, Viros A, Groenen PJTA, Sanchez-Laorden B, Gilhuis JH, et al. Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes. Cancer Discov. 2013 ;3(4) :458-69. doi : 10.1158/2159-8290.CD-12-0464.
    Open DOISearch in Google ScholarBack to article
  21. Burd CE, Liu W, Huynh MV, Waqas MA, Gillahan JE, Clark KS, et al. Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma. Cancer Discov. 2014;4(12):1418-29. doi: 10.1158/2159-8290.CD-14-0729.
    Open DOISearch in Google ScholarBack to article
  22. AACR Project GENIE Consortium. AACR Project GENIE: Powering Precision Medicine through an International Consortium. Cancer Discov. 2017;7(8):818-31. doi: 10.1158/2159-8290.CD-17-0151.
    Open DOISearch in Google ScholarBack to article
DOI: https://doi.org/10.34763/jmotherandchild.20212501.d-21-00007 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488
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Language: English
Page range: 19 - 24
Submitted on: Mar 7, 2021
|
Accepted on: Apr 22, 2021
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Published on: Oct 11, 2021
Published by: Institute of Mother and Child
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
Congenital melanocytic nevi,
CMN,
GCMN,
NRAS
Related subjects:
Medicine,
Clinical medicine,
Pediatrics and juvenile medicine,
Paediatric haematology and oncology,
Public health

© 2021 Katarzyna Wertheim-Tysarowska, Orest Szczygielski, Katarzyna Seliga, Andrzej Tysarowski, Jerzy Bal, Elżbieta Michalak, Agnieszka Magdalena Rygiel, Ewa Sawicka, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.

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