Immunoglobulins content in colostrum, transitional and mature milk of Bangladeshi mothers: Influence of parity and sociodemographic characteristics

Akhter, Hashemi; Aziz, Farina; Ullah, Fahim R.; Ahsan, Monira; Islam, Sheikh N.

doi:10.34763/jmotherandchild.20202403.2032.d-20-00001

Figures & Tables

Immunoglobulins (IgA, IgG and IgM) concentration (g/L) in colostrum, transitional and mature milk_

Immunoglobulins (n = 38)	Concentration (g/L) of immunoglobulins in human milk				Statistics

	Mean ± SD	95% CI (lower-upper)	Ranges	t-statistics	Correlation co-efficient
IgA
Colostrum^a	5.92 ± 1.5	5.45–6.40	3.16–8.97	t^ab = 7.15 P^ab = 0.000**	r^ab = 0.028 P^ab = 0.94
Transitional milk^b	3.85 ± 0.64	3.64–4.05	1.35–4.69	t^bc = 1.02 P^bc = 0.32	r^bc = 0.33 P^bc = 0.04^*
Mature milk^c	3.72 ± 0.68	3.50–3.93	1.79–4.43	t^ac = 8.28 P^ac = 0.000**	r^ac = 0.001 P^ac = 0.543
IgG
Colostrum^a	0.10 ± 0.03	0.09–0.11	0.04–0.17	t^ab = =4.03 P^ab = 0.000^**	r^ab = 0.002 P^ab = 0.537
Transitional milk^b	0.12 ± 0.02	0.11–0.12	0.08–0.15	t^bc = 1.00 P^bc = 0.32	r^bc = 0.51 P^bc = 0.001^**
Mature milk^c	0.11 ± 0.02	0.11–0.12	0.07–0.17	t^ac = 2.66 P^ac = 0.011*	r^ac = 0.005 P^ac = 0.654
IgM
Colostrum^a	0.44 ± 0.10	0.41–0.47	0.23–0.59	t^ab = 21.37 P^ab = 0.000^**	r^ab = 0.023 P^ab = 0.345
Transitional milk^b	0.10 ± 0.02	0.09–0.10	0.04–0.14	t^bc = 1.28 P^bc = 0.21	r^bc = 0.34 P^bc = 0.04^*
Mature milk^c	0.09 ± 0.02	0.08–0.10	0.06–0.15	t^ac = 20.71 P^ac = 0.000^**	r^ac = 0.005 P^ac = 0.345

Association of immunoglobulins concentration at different stages of lactation with maternal characteristics and family income_

Maternal characteristics (n = 38)	% (n)	Colostrum (g/L)			Transitional milk (g/L)			Mature milk (g/L)

			Mean ± SD			Mean ± SD			Mean ± SD

		IgA	IgG	IgM	IgA	IgG	IgM	IgA	IgG	IgM
Age (years)
18–20	34.0 (13)	6.04 ± 1.3	0.10 ± 0.03	0.42 ± 0.1	3.81 ± 0.5	0.13 ± 0.02	0.10 ± 0.02	3.78 ± 0.8	0.12 ± 0.02	0.09 ± 0.02
21–25	37.0 (14)	6.01 ± 1.4	0.10 ± 0.03	0.42 ± 0.1	3.84 ± 0.8	0.12 ± 0.02	0.10 ± 0.02	3.72 ± 0.7	0.11± 0.02	0.09 ± 0.02
≥26	29.0 (11)	5.9 ± 1.5	0.10 ± 0.02	0.41 ± 0.1	3.82 ± 0.6	0.12 ± 0.02	0.10 ± 0.03	3.80 ± 0.7	0.11 ± 0.02	0.09 ± 0.03
P-value		0.98	0.74	0.19	0.78	0.69	0.94	0.99	0.57	0.39
Parity
Primiparous	34.0 (13)	6.58 ± 1.3	0.10 ± 0.022	0.44 ± 0.1	3.73 ± 0.9	0.13 ± 0.02	0.11 ± 0.02	3.78 ± 0.8	0.12 ± 0.02	0.09 ± 0.03
Multiparous	66.0 (25)	5.58 ± 1.5	0.10 ± 0.03	0.44 ± 0.1	3.91 ± 0.5	0.11 ± 0.02	0.09 ± 0.02	3.69 ± 0.6	0.11 ± 0.02	0.09 ± 0.02
P-value		0.05	0.56	0.94	0.42	*0.03	0.05	0.70	0.76	0.82
BMI (kg/m²)
<18.5	11.0 (04)	4.26 ± 1.2	0.08 ± 0.02	0.43 ± 0.1	3.91 ± 0.3	0.11 ± 0.01	0.08 ± 0.02	3.63 ± 0.9	0.10 ± 0.02	0.09 ± 0.00
18.6–25.0	71.0 (27)	6.09 ± 1.3	0.10 ± 0.03	0.44 ± 0.1	3.83 ± 0.7	0.12 ± 0.02	0.10 ± 0.02	3.67 ± 0.7	0.12 ± 0.02	0.09 ± 0.02
≥25.01	18.0 (07)	6.21 ± 1.9	0.10 ± 0.4	0.44 ± 0.1	3.86 ± 0.6	0.12 ± 0.02	0.11 ± 0.02	3.96 ± 0.4	0.11 ± 0.03	0.09 ± 0.03
P-value		0.08	0.69	0.94	0.99	0.37	0.17	0.74	0.47	0.74
Family Income (BDT)
Up to 4000	29.0 (11)	5.06 ± 1.4	0.10 ± 0.03	0.43 ± 0.1	3.88 ± 0.5	0.12 ± 0.02	0.10 ± 0.02	3.72 ± 0.7	0.11 ± 0.02	0.09 ± 0.02
4001–8000	47.0 (18)	5.94 ± 1.5	0.10 ± 0.02	0.44 ± 0.1	3.83 ± 0.8	0.12 ± 0.02	0.10 ± 0.02	3.80 ± 0.7	0.11 ± 0.02	0.09 ± 0.02
≥8001	24.0 (09)	6.22 ± 1.3	0.10 ± 0.04	0.46 ± 0.1	3.85 ± 0.6	0.12 ± 0.02	0.10 ± 0.03	3.56 ± 0.7	0.12 ± 0.03	0.09 ± 0.03
P-value		0.09	0.90	0.73	0.98	0.74	0.92	0.69	0.37	0.96

Maternal characteristics_

Characteristics	% (n)	Mean ± SD
Maternal age (years)		22.84 ± 4.8
18–20	34.0 (13)
21–25	37.0 (14)
≥26	29.0 (11)
Parity		1.78 ± 0.9
Primiparous	34.0 (13)
Multiparous	66.0 (25)
BMI (kg/m²)		24.65 ± 0.71
<18.5	11.0 (04)
18.6–25.0	71.0 (27)
≥25.01	18.0 (07)
Family income (BDT )		6131 ± 287
Up to 4000	29.0 (11)
4001–8000	47.0 (18)
≥8001	24.0 (09)

Immunoglobulins content in colostrum, transitional and mature milk of Bangladeshi mothers: Influence of parity and sociodemographic characteristics

Figures & Tables

Immunoglobulins (IgA, IgG and IgM) concentration (g/L) in colostrum, transitional and mature milk_

Association of immunoglobulins concentration at different stages of lactation with maternal characteristics and family income_

Maternal characteristics_

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