Dress syndrome in 7-year-old male child – case report

Monika Prylińska; Marta Dworakowska-Kicińska; Aneta Krogulska

doi:10.34763/jmotherandchild.20202403.2019.d-20-00006

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Dress syndrome in 7-year-old male child – case report

Journal of Mother and Child

Volume 24 (2020): Issue 3 (September 2020)

By: Monika Prylińska , Marta Dworakowska-Kicińska and Aneta Krogulska

Open Access

|Jan 2021

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) is a severe drug-induced hypersensitivity reaction, which, due to the asymptomatic beginning and non-specific nature of symptoms, is hard to identify. This report presents the case of a 7-year-old boy, who was referred to the Department of Paediatric Surgery with fever up to 38°C, vomiting and diarrhoea, accompanied by erythematous, maculopapular rash. Based on laboratory and radiology tests and specific diagnostic criteria, DRESS syndrome was diagnosed. The presented case report emphasises the need to carry out differential diagnosis, including the potentially life-threatening DRESS syndrome, with common symptoms in children such as fever and rash.

References

Bocquet H, Bagot M, Roujeau JC. Drug-induced pseudolymphoma and drug hypersensitivity syndrome (Drug Rash with Eosinophilia and Systemic Symptoms: DRESS). Semin Cutan Med Surg. 1996;15(4):250–7. doi: 10.1016/s1085-5629(96)80038-1.
Open DOI Search in Google Scholar Back to article
Callot V, Roujeau JC, Bagot M, Wechsler J, Chosidow O, Souteyrand P, et al. Drug-induced pseudolymphoma and hypersensitivity syndrome. Two diferent clinical entities. Arch Dermatol. 1996;132(11):1315–21. doi: 10.1001/archderm.1996.03890350057010.
Open DOI Search in Google Scholar Back to article
Choudhary S, McLeod M, Torchia D, Romanelli P. Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. J Clin Aesthet Dermatol. 2013;6(6):31–7.
Search in Google Scholar Back to article
Tennis P, Stern RS. Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study. Neurology. 1997;49(2):542–6. doi: 10.1212/wnl.49.2.542.
Open DOI Search in Google Scholar Back to article
Metterle L, Hatch L, Seminario-Vidal L. Pediatric drug reaction with eosinophilia and systemic symptoms: a systematic review of the literature. Pediatr Dermatol. 2020;37(1):124–9. doi: 10.1111/pde.14044.
Open DOI Search in Google Scholar Back to article
Roquin G, Peres M, Lerolle N, Dib N, Mercat A, Croue A, et al. First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis. Ann Pharmacother. 2010;44(12):1998–2000. doi: 10.1345/aph.1P350.
Open DOI Search in Google Scholar Back to article
Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Halevy S, Davidovici BB, Mockenhaupt M, et al. Variability in the clinical pattern of cutaneous side-efects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br J Dermatol. 2007;156(3):609–11. doi: 10.1111/j.1365-2133.2006.07704.x. Comment on: Peyrière H, Dereure O, Breton H, Demoly P, Cociglio M, Blayac JP, Hillaire-Buys D; Network of the French Pharmacovigilance Centers. Variability in the clinical pattern of cutaneous side-efects of drugs with systemic symptoms: does a DRESS syndrome really exist? Br J Dermatol. 2006;155(2):422–8. doi: 10.1111/j.1365-2133.2006.07284.x.
Open DOI Search in Google Scholar Back to article
Chaiken BH, Goldberg BI, Segal JP. Dilantin sensitivity; report of a case of hepatitis with jaundice, pyrexia and exfoliative dermatitis. N Engl J Med. 1950;242(23):897–8. doi: 10.1056/NEJM195006082422304.
Open DOI Search in Google Scholar Back to article
Shear NH, Spielberg SP. Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk. J Clin Invest. 1988;82(6):1826– 32. doi: 10.1172/JCI113798.
Open DOI Search in Google Scholar Back to article
Criado PR, Criado RF, Avancini JM, Santi CG. Drug reaction with Eosinophilia and Systemic Symptoms (DRESS)/Drug-induced Hypersensitivity Syndrome (DIHS): a review of current concepts. An Bras Dermatol. 2012;87(3):435–49. doi: 10.1590/s0365-05962012000300013.
Open DOI Search in Google Scholar Back to article

Articles in this issue

DOI: https://doi.org/10.34763/jmotherandchild.20202403.2019.d-20-00006 | Journal eISSN: 2719-535X | Journal ISSN: 2719-6488

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Language: English

Page range: 45 - 48

Published on: Jan 12, 2021

Published by: Institute of Mother and Child

In partnership with: Paradigm Publishing Services

Publication frequency: 1 issue per year

Keywords:

child,

DRESS,

drug reaction with eosinophilia and systemic symptoms,

drug-induced hypersensitivity,

paediatric

Related subjects:

Medicine,

Clinical medicine,

Pediatrics and juvenile medicine,

Paediatric haematology and oncology,

Public health

© 2021 Monika Prylińska, Marta Dworakowska-Kicińska, Aneta Krogulska, published by Institute of Mother and Child
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 24 (2020): Issue 3 (September 2020)