Fig. 1.
Epidemiological trends of Micrococcus luteus bloodstream infection (BSI) in the First Medical Center of the Chinese People’s Liberation Army General Hospital. Incidence was calculated as cases divided by the admission number of the year. Data for 2019 was unavailable due to a lack of hospital admission number.
Table I
Characteristics of the patients with M. luteus BSI.
| Variable | Value |
|---|---|
| Age (year), mean ± SD (range) | 51.9 ± 22.0 (2-92) |
| Age ≤ 12 | 8 (8.2) |
| Age ≥ 60 | 38 (39.2) |
| Male | 61 (62.9) |
| BMI, mean ± SD (range) | 22.6 ± 4.5 (13.4-35.4) |
| SOFA Score, mean ± SD (range) | 1.4 ± 1.8 (0-8) |
| Infection type | |
| Hospital-acquired | 70 (72.2) |
| Community-acquired | 27 (27.8) |
| Hospitalization time (day), mean ± SD (range) | 32.2 ± 36.4 (6-267) |
| Polymicrobial bloodstream infection | 5 (5.2) |
| Symptom | |
| Fever | 87 (89.7) |
| Chill | 18 (18.6) |
| Fatigue | 12 (12.4) |
| Maximal body temperature (T, °C), mean ± SD (range) | 38.7 ± 0.9 (36.5-41.0) |
| 37.2 < T ≤ 38 | 8 (8.2) |
| 38 < T ≤ 39 | 43 (44.3) |
| 39<T<41 | 36 (37.1) |
| WBC count (× 109/l), mean ± SD (range) | 7.9 ± 4.3 (0.6-21.8) |
| WBC count above 10 × 109/l (n = 95) | 31 (32.6) |
| NEUT%, mean ± SD (range) | 72.2 ± 18.3 (4-97.6) |
| NEUT% above 70% (n = 92) | 58 (63.0) |
| CRP concentration (mg/dl), mean ± SD (range) | 5.5 ± 6.4 (0.09-33.5) |
| CRP above 0.8 mg/dl (n = 79) | 60 (75.9) |
| Underlying diseases | |
| Malignancy | 47 (48.5) |
| Immune diseases | 15 (15.5) |
| Infectious diseases | 13 (13.4) |
| Risk factors | |
| Underwent invasive surgery | 39 (40.2) |
| With indwelling catheter | 37 (38.1) |
| ICU stay | 15 (15.5) |
| Any of the above | 65 (67.0) |
| Outcome | |
| Survive | 94 (96.9) |
| Died | 3 (3.1) |
| Causes of death | |
| Lung infection, renal failure | 1 (33.3) |
| Pancreatic cancer, hepatic encephalopathy | 1 (33.3) |
| Acute leukemia | 1 (33.3) |
Table II
Results of antimicrobial susceptibility tests
| Antimicrobial agent | Number of samples | Average diameter of inhibition zone (mm) |
|---|---|---|
| Linezolid | 90 | 36 |
| Cefoxitin | 88 | 35 |
| Rifampin | 87 | 33 |
| Cefazolin | 89 | 32 |
| Penicillin | 90 | 32 |
| Ampicillin-sulbactam | 89 | 31 |
| Cefuroxime | 88 | 31 |
| Trimethoprim-sulfamethoxazole | 90 | 29 |
| Ertapenem | 90 | 27 |
| Gentamycin | 90 | 26 |
| Vancomycin | 88 | 25 |
| Levofloxacin | 90 | 25 |
| Clindamycin | 90 | 25 |
| Erythromycin | 89 | 15 |