References
- Aarabi, S., Kettani, K., Chauiyakh, O., Bouganssa, T., El Fahime, E., & Et-tahir, A. (2024). Bioaccumulation of heavy metals in five species of fish obtained from the estuary of Rabat, Morocco. Tropical Journal of Natural Product Research, 8 (4), 6765–6770. https://doi.org/10.26538/tjnpr/v8i4
- Abbas, M. M. M. (2023). Heavy metal levels and cancer risk assessments of the commercial Denis (Sparus aurata) collected from Bardawil Lake and private fish farm waters as a cultured source, Egypt. Biological Trace Element Research, 202, 2864–2877. https://doi.org/10.1007/s12011-023-03880-0
- Abd-Elghany, S. M., Sayed-Ahmed, M. Z., Rahmo, H. M., Zakaria, A. I., Ahmad, S., Alam, N., Ali, M. S., & Sallam, K. I. (2024). Carcinogenic and non-carcinogenic health risks associated with the consumption of fishes contaminated with heavy metals from Manzala Lake, Egypt. Marine Pollution Bulletin, 202, Article 116391. https://doi.org/10.1016/j.marpolbul.2024.116391
- Abdel-Kader, H. H., & Mourad, M. H. (2022). Investigation of a balanced healthy diet for human consumption of Clarias gariepinus and Oreochromis niloticus species from Lake Manzalah (Egypt), and target cancer/hazard quotient (non-cancer) risk metrics. Egyptian Journal of Aquatic Biology and Fisheries, 26(4), 1151–1170. https://doi.org/10.21608/ejabf.2022.256392
- Ahmed, M. K., Shaheen, N., Islam, M. S., Habibullah-al-Mamun, M., Islam, S., Mohiduzzaman, M., & Bhattacharjee, L. (2015). Dietary intake of trace elements from highly consumed cultured fish (Labeo rohita, Pangasius pangasius, and Oreochromis mossambicus) and human health risk implications in Bangladesh. Chemosphere, 128, 284–292. https://doi.org/10.1016/j.chemosphere.2015.01.035
- Artar, E., Olgunoglu, M. P., & Olgunoglu, I. A. (2024). Evaluation of heavy metal accumulation and associated human health risks in three commercial marine fish species from the Aegean Sea, Türkiye. Italian Journal of Food Science, 36(2), 136–149. https://doi.org/10.15586/ijfs.v36i2.2474
- ATSDR. (2005). Agency for toxic substances and disease registry, toxicological profile for Zinc. U.S. Department of Health and Human Services, Public Health Service, Atlanta. https://www.atsdr.cdc.gov/toxprofiles/tp60-p.pdf
- ATSDR. (2023). Agency for toxic substances and disease registry, toxicological profile for Copper. https://www.atsdr.cdc.gov/toxprofiles/tp132-c1.pdf
- Aydın-Önen, S., & Öztürk, M. (2017). Investigation of heavy metal pollution in eastern Aegean Sea coastal waters by using Cystoseira barbata, Patella caerulea, and Liza aurata as biological indicators. Environmental Science and Pollution Research, 24(8), 7310–7334. https://doi.org/10.1007/s11356-016-8226-4
- Azadeh, A., Takdastan, A., & Alivand, S. (2022). Determination of heavy metals including Hg, Pb, Cd, and Cr in edible fishes Liza abu, Brachirus orientalis and attributed cancer and non-cancer risk assessment. Environmental Health Engineering and Management Journal, 9(2), 157–164. https://doi.org/10.15171/ehem.2022.26
- Babuji, P., Thirumalaisamy, S., Duraisamy, K., & Periyasamy, G. (2023). Human health risks due to exposure to water pollution: A review. Water, 15(14), 2532. https://doi.org/10.3390/w15142532
- Barone, G., Storelli, A., Garofalo, R., Busco, V. P., Quaglia, N. C., Centrone, G., & Storelli, M. M. (2015). Assessment of mercury and cadmium via seafood consumption in Italy: Estimated dietary intake (EWI) and target hazard quotient (THQ). Food Additives & Contaminants: Part A, 32(8), 1277–1286. https://doi.org/10.1080/19440049.2015.1055594
- Bat, L., Öztekin, H. C., & Üstün, F. (2015). Heavy metal levels in four commercial fishes caught in Sinop coasts of the Black Sea, Turkey. Turkish Journal of Fisheries and Aquatic Sciences, 15(2), 393–399. https://doi.org/10.4194/1303-2712-v15_2_25
- Bernhard, M. (1976). Manual of methods in aquatic environment research (Technical Paper No. 158 FIRI/T 158). Rome: FAO Fisheries. https://www.vliz.be/imisdocs/publications/381361.pdf
- Bilgin, M., Uluturhan, E., Darilmaz, E., & Katalay, S. (2023). Combined evaluation of multi-biomarkers and metal bioaccumulations in two different fish species (Sparus aurata and Chelon labrosus) from Izmir Bay, Türkiye (Aegean Sea): Spatial, temporal and tissue-specific approaches. Marine Pollution Bulletin, 197, Article 115709. https://doi.org/10.1016/j.marpolbul.2023.115709
- Chandrapalan, T., & Kwong, R. W. M. (2021). Functional significance and physiological regulation of essential trace metals in fish. The Journal of Experimental Biolgy, 224(24), jeb238790. https://doi.org/10.1242/jeb.238790
- Edo, G. I., Samuel, P. O., Oloni, G. O., Ezekiel, G. O., Ikpekoro, V. O., Obasohan, P., Ongulu, J., Otunuya, C. F., Opiti, A. R., Ajakaye, R. S., Essagha, A. E. A., & Agbo, J. J. (2024). Environmental persistence, bioaccumulation, and ecotoxicology of heavy metals. Chemistry and Ecology, 40(3), 322–349. https://doi.org/10.1080/02757540.2024.2306839
- FAO/WHO. (2004). Summary and conclusions of the sixty-first meeting of the Joint FAO/WHO expert committee on food additives (JECFA). Retrived from ftp://ftp.fao.org/es/esn/jecfa/jecfa61sc.pdf
- FAO/WHO. (2010). Summary report of the seventy-third meeting of JECFA, Joint FAO/WHO expert committee on food additives (JECFA). Geneva. https://openknowledge. fao.org/server/api/core/bitstreams/a3da64ef-146b-4818-9cdb-2a37e1fe59d9/content
- FAO/WHO. (2011). Food Standards programme codex committee on contaminants in foods Food (Report No. CF/5 INF/1) (pp. 1–89). Geneva, Switzerland: WHO. https://www.fao.org/input/download/report/758/REP11_CFe.pdf
- Farhat, N., Hidri, R., Ghnaya, T., Abdelly, C., & Zorrig, W. (2025). The risk of cadmium accumulation in lettuce (Lactuca sativa): How can zinc help? Euro-Mediterranean Journal for Environmental Integration, 10(5), 4145–4159. https://doi.org/10.1007/s41207-025-00845-8
- Gawade, L., Chari, N. V. H., Sarma, V. V., & Ingole, B. S. (2013). Variation in heavy metals concentration in the edible oyster Crassostrea madrasensis, clam Polymesoda erosa and grey mullet Liza aurata from coastline of India. Indian Journal of Science, 2(4), 59–63. http://www.discovery.org. in/ijs.htm
- Hosseini, S. M., Vajdi, R., Monsef Rad, S. F., Dahmardeh Behrooz, R., Chamanara, V., & Hosseini, S. V. (2022). Risk assessment of trace elements bioaccumulated in golden gray mullet (Liza aurata) harvested from the southern Caspian Sea. Journal of Great Lakes Research, 48(4), 1079–1086. https://doi.org/10.1016/j.jglr.2022.04.010
- Ilkyaz, A., Fırat, K., Saka, Ş, & Kınacıgil, H. T. (2006). Age, growth, and sex ratio of golden grey mullet, Liza aurata (Risso, 1810) in Homa Lagoon (Izmir Bay, Aegean Sea). Turkish Journal of Zoology, 30(3), 279–284.
- Iyiola, A. O., Kolawole, A. S., Setufe, S. B., Bilikoni, J., Ofori, E., & Ogwu, M. C. (2024). Fish as a sustainable biomonitoring tool in aquatic environments. In S. C. Izah, M. C. Ogwu, & H. Hamidifar (Eds.), Biomonitoring of pollutants in the Global South. Springer. https://doi.org/10.1007/978-981-97-1658-6_12
- Jelodar, H. T., Sharifzadeh Baei, M., Najafpour, S. H., & Fazli, H. (2011). The comparison of heavy metals concentrations in different organs of Liza aurata inhabiting in southern part of Caspian Sea. World Applied Sciences Journal 14 (Special Issue of Food and Environment), 96–100.
- Jomova, K., Alomar, S. Y., Nepovimova, E., Kuca, K., & Valko, M. (2025). Heavy metals: Toxicity and human health effects. Archives of Toxicology, 99(1), 153–209. https://doi.org/10.1007/s00204-024-03903-2
- Kadim, M. K., & Risjani, Y. (2022). Biomarker for monitoring heavy metal pollution in aquatic environment: An overview toward molecular perspectives. Emerging Contaminants, 8, 195–205. https://doi.org/10.1016/j.emcon.2022.02.003
- Kamidis, N., Sapounidis, A., Spanos, T., Chatzichristou, C., Topi, V., Triantafillidis, S., Karampetsis, D., Papadopoulou, P., Mitkidou, S., Kokkinos, N., Ene, A., & Stamatis, N. (2024). Trace elements in two endemic fish species (Barbus strumicae, Karaman 1955 and Squalius orpheus, Kottelat & Economidis, 2006) of Nestos River (NE Greece): Levels, organ bioaccumulation and potential health risk. Marine Pollution Bulletin, 208, Article 116967. https://doi.org/10.1016/j.marpolbul.2024.116967
- Kaya, M. (2017). Commercial marine fish of Izmir (pp. 33–42). Izmir Fisheries. Izmir Metropolitan Municipality.
- Kontas, A., Alyuruk, H., Bilgin, M., Uluturhan, E., Ünlüoğlu, A., Darilmaz, E., & Altay, O. (2022). Metal bioaccumulation and potential health risk assessment in different tissues of three commercial fish species (Merluccius merluccius, Mullus barbatus, and Pagellus erythrinus) from Edremit Bay (Aegean Sea), Turkey. Biological Trace Element Research, 200(2), 868–880. https://doi.org/10.1007/s12011-021-02683-5
- Korkmaz, C., Ay, Ö, Ersoysal, Y., Köroğlu, M. A., & Erdem, C. (2019). Heavy metal levels in muscle tissues of some fish species caught from north-east Mediterranean: Evaluation of their effects on human health. Journal of Food Composition and Analysis, 81(1), 1–9. https://doi.org/10.1016/j.jfca.2019.04.005
- Kwong, R. W. (2024). Trace metals in the teleost fish gill: Biological roles, uptake regulation, and detoxification mechanisms. Journal of Comparative Physiology B, 194(5), 749–763. https://doi.org/10.1007/s00360-024-01565-1
- Lall, S. P., & Kaushik, S. J.(2021). Nutrition and metabolism of minerals in Fish. Animals, 11(9), 2711. https://doi.org/10.3390/ani11092711
- Leblanc, J.C., Guérin, T., Noёl, L., Calamassi-Tran, G., Volatier, J.L., & Verger, P. (2005). Dietary exposure estimates of 18 elements from the 1st French total diet study. Food Additives & Contaminants, 22(7), 624–641. https://doi.org/10.1080/02652030500135367
- Le, T. T., Kim, K. W., Nguyen, D. Q., & Ngo, H. T. T. (2023). Trace element contamination in rice and its potential health risks to consumers in north-central Vietnam. Environmental Geochemistry and Health, 45(10), 3361–3375. https://doi.org/10.1007/s10653-022-01415-5
- Maulvault, A. L., Anacleto, P., Barbosa, V., Sloth, J. J., Rasmussen, R. R., Tediosi, A., Fernandez-Tejedor, M., van den Heuvel, F. H. M., Kotterman, M., & Marques, A. (2015). Toxic elements and speciation in seafood samples from different contaminated sites in Europe. Environmental Research, 143(Pt B), 72–81. https://doi.org/10.1016/j.envres.2015.09.016
- Mohammadi, M. J., Kiani, F., Farhadi, M., Ghanbari, S., Jalili, D., & Mirzaei, L. (2024). Evaluation of carcinogenic risk of heavy metals due to consumption of rice in Southwestern Iran. Toxicology Reports, 12, 578–583. https://doi.org/10.1016/j.toxrep.2024.01.045
- Mol, S., Karakulak, F. S., & Ulusoy, S. (2017). Assessment of potential health risks of heavy metals to the general public in Turkey via consumption of red mullet, whiting, turbot from the southwest Black Sea. Turkish Journal of Fisheries and Aquatic Sciences, 17(6), 1135–1143. https://doi.org/10.4194/1303-2712-v17_6_07
- Monier, M. N., Soliman, A. M., & Al-Halani, A. A. (2023). The seasonal assessment of heavy metals pollution in water, sediments, and fish of grey mullet, red seabream, and sardine from the Mediterranean coast, Damietta, North Egypt. Regional Studies in Marine Science, 57(347), 102744. https://doi.org/10.1016/j.rsma.2022.102744
- Naeem, S., Ashraf, M., Babar, M. E., Zahoor, S., & Ali, S. (2021). The effects of some heavy metals on some fish species. Environmental Science and Pollution, 28(20), 25566–25578. https://doi.org/10.1007/s11356-021-12385-z
- Nyarko, E., Boateng, C. M., Asamoah, O., Edusei, M. O., & Mahu, E. (2023). Potential human health risks associated with ingestion of heavy metals through fish consumption in the Gulf of Guinea. Toxicology Reports, 10, 117–123. https://doi.org/10.1016/j.toxrep.2023.01.005
- Oliveira, M., Ahmad, I., Maria, V. L., Serafim, A., Bebianno, M. J., Pacheco, M., & Santos, M. A. (2010). Hepatic metallothionein concentrations in the golden grey mullet (Liza aurata): Relationship with environmental metal concentrations in a metal-contaminated coastal system in Portugal. Marine Environmental Research, 69(4), 227–233. https://doi.org/10.1016/j.marenvres.2009.10.012
- Pan, Y., Peng, H., Xie, S., Zeng, M., & Huang, C. (2019). Eight elements in soils from a typical light industrial city, China: Spatial distribution, ecological assessment, and the source apportionment. International Journal of Environmental Research and Public Health, 16(14), 2591. https://doi.org/10.3390/ijerph16142591
- Ramírez Ortega, D., González Esquivel, D. F., Blanco Ayala, T., Pineda, B., Gómez Manzo, S., Marcial Quino, J., Carrillo Mora, P., & Pérez de la Cruz, V. (2021). Cognitive impairment induced by lead exposure during lifespan: Mechanisms of lead neurotoxicity. Toxics, 9(2), 23. https://doi.org/10.3390/toxics9020023
- Saleem, M., Iqbal, J., Shi, Z., Garrett, S. H., & Shah, M. H. (2022). Distribution and bioaccumulation of essential and toxic metals in tissues of Thaila (Catla catla) from a natural lake, Pakistan, and its possible health impact on consumers. Journal of Marine Science and Engineering, 10(7), 933. https://doi.org/10.3390/jmse10070933
- Salem, Z. B., & Ayadi, H. (2016). Heavy metal accumulation in Diplodus annularis, Liza aurata, and Solea vulgaris relevant to their concentration in water and sediment from the southwestern Mediterranean (coast of Sfax). Environmental Science and Pollution Research, 23(13), 13895–13906. https://doi.org/10.1007/s11356-016-6531-6
- Shah, S. B. (2021). Heavy metals in the marine environment— an overview. In Heavy metals in scleractinian corals (pp. 1–98). Springer Briefs in Earth Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-73613-2_1
- Shahjahan, M., Taslima, K., Rahman, M. S., Al-Emran, M., Alam, S. I., & Faggio, C. (2022). Effects of heavy metals on fish physiology - A review. Chemosphere, 300, 134519. https://doi.org/10.1016/j.chemosphere.2022.134519
- Sharma, A. K., Sharma, M., Sharma, S., Malik, D. S., Sharma, M., Sharma, M., & Sharma, A. K. (2024). A systematic review on assessment of heavy metals toxicity in freshwater fish species: Current scenario and remedial approaches. Journal of Geochemical Exploration, 262, Article 107472. https://doi.org/10.1016/j.gexplo.2024.107472
- Sigamani, S., Jebasingh, A. D., Dhas, Y. T., Sundaram, S., Babu, U., Kolandhasamy, P., Syed, A., & Elgorban, A. M. (2024). Bioaccumulation and health risk of metal contamination from different tiers of food chain in Ennore estuary, Southeast coast of India. Marine Pollution Bulletin, 200, Article 116154. https://doi.org/10.1016/j.marpolbul.2024.116154
- Taş, E. Ç, Başaran, A., Sunlu, U., & Salman, A. (2024). Heavy metal concentration and potential health risk assessment for the European eel (Anguilla anguilla, Linnaeus 1758) from the Gediz Delta (Eastern Aegean, Türkiye). Oceanological and Hydrobiological Studies, 53(2), 144–152. https://doi.org/10.26881/oahs-2024.2.05
- Taş, E. Ç, Filipuçi, I., Türker Çakır, D., Beyaztaş, S., Sunlu, U., Toğulga, M., Özaydin, O., & Arslan, O. (2011). Heavy metal concentrations in tissues of edible fish (Mullus barbatus L., 1758) from Çandarli Bay (Turkey). Fresenius Environmental Bulletin, 20(11), 2834–2839.
- Telahigue, K., Rabeh, I., Mdaini, Z., Ghali, R., Chouba, L., & Hajji, T. (2024). Human health risk assessment of heavy metal(oid)s in four fish species harvested from the Bizerte Lagoon (Tunisia). Bulletin de l’Institut National des Sciences et Technologies de la Mer, 49, 61–77. https://www.instm-bulletin.tn/index.php/bulletin/article/view/1709
- Tokaç, A. (2017). Commercial marine fish of Izmir. Izmir Fisheries. Izmir Metropolitan Municipality, Konak, Izmir, 17–25.
- TUIK. (2023). Turkish Statistical Institute, Aquaculture Statistics 2022 in Türkiye. Accessed August 4, 2023, from https://biruni.tuik.gov.tr/medas/?kn=97&locale=tr
- Turan, F., Yilmaz, M. B., Yola, M. L., Ergenler, A., Ilgaz, N. S., & Oksuz, H. (2022). Bioaccumulation of trace metals and genotoxicity responses in Liza aurata as an indicator of industrial pollution. Ecotoxicology, 31 (9), 1390–1402. https://doi.org/10.1007/s10646-022-02591-x
- Türkmen, M., Tepe, Y., Türkmen, A., & Ateş, A. (2012). Investigation of metals in tissues of fish species from Akyatan Lagoon. Fresenius Environmental Bulletin, 21(11c), 3562–3567.
- US EPA. (1989). Risk assessment guidance for superfund, Vol. I: Human Health Evaluation Manual (No. EPA/540/1-89/002). Office of Emergency and Remedial Response, Washington, DC.
- US EPA. (2007). Concepts, methods, and data sources for cumulative health risk assessment of multiple chemicals, exposures and effects: A resource document. US Environmental Protection Agency, Washington, DC.
- US EPA. (2009). Risk-based concentration table. Environmental Protection Agency. Philadelphia PA, Washington DC.
- US EPA. (2023). Integrated Risk Information System (IRIS) on Copper. https://iris.epa.gov/
- US EPA. (2024). Regional Screening Level (RSL) – Generic Tables: November 2024. https://www.epa.gov/risk/regional-screening-levels-rsls-users-guide#target
- Usero, J., Izquierdo, C., Morillo, J., & Gracia, I. (2003). Heavy metals in fish (Solea vulgaris, Anguilla anguilla and Liza aurata) from salt marshes on the southern Atlantic coast of Spain. Environment International, 29(7), 949–956. https://doi.org/10.1016/S0160-4120(03)00061-8
- Ustaoğlu, F., & Yüksel, B. (2024). Bioaccumulation of metals in muscle tissues of economically important fish species from Black Sea lagoon lakes in Türkiye: Consumer health risk and nutritional value assessment. Microchemical Journal, 205, 111337. https://doi.org/10.1016/j.microc.2024.111337
- Varol, M., Kaçar, E., Sünbül, M. R., & Islam, A. R. M. T. (2022). Levels of metals and elements in tissues of fish species in the Kızılırmak River (Turkey) and assessment of health risks and nutritional benefits. Environmental Research, 214 (Pt 1), Article 113791. https://doi.org/10.1016/j.envres.2022.113791
- Wei, Y., Zhang, J., Zhang, D., Tu, T., & Luo, L. (2014). Metal concentrations in various fish organs of different fish species from Poyang Lake, China. Ecotoxicology and Environmental Safety, 104, 182–188. https://doi.org/10.1016/j.ecoenv.2014.03.001
- Wosnick, N., Niella, Y., Hammerschlag, N., Chaves, A. P., Hauser-Davis, R. A., da Rocha, R. C., Jorge, M. B., de Oliveira, R. W. S., & Nunes, J. L. S. (2021). Negative metal bioaccumulation impacts on systemic shark health and homeostatic balance. Marine Pollution Bulletin, 168, Article 112398. https://doi.org/10.1016/j.marpolbul.2021.112398
- Yuvka, İ, Kosker, A. R., Durmus, M., Ucar, Y., & Ozogul, Y. (2025). Seasonal changes in the elemental composition of five valuable fish species (sparidae) from Bozcaada, North Aegean Sea: A health risk and nutritional benefit assessment. Foods, 14(2), 324. https://doi.org/10.3390/foods14020324
- Zaghloul, G. Y., Eissa, H. A., Zaghloul, A. Y., Kelany, M. S., Hamed, M. A., & El Moselhy, K. M. (2024). Impact of some heavy metal accumulation in different organs on fish quality from Bardawil Lake and human health risks assessment. Geochemical Transactions, 25(1), 1. https://doi.org/10.1186/s12932-023-00084-2