Simultaneous determination of cytochrome P450 1A, 2A and 3A activities in porcine liver microsomes
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|Jan 2013References
- Alden PG, Plumb RS, Jones MD, Rainville PD, Shave D. (2010). A rapid ultraperformance liquid chromatography/tandem mass spectrometric methodology for theanalysis of Pooled and Cocktail cytochrome P450 assays.147-154.
- Anzenbacher P, Anzenbacherová E. (2001). Cytochromes P450 and metabolism of xenobiotics.737-747.
- He F, Bi HC, Xie ZY, Zuo Z, Li JK, Li X, Zhao LZ, Chen X, Huang M. (2007). Rapid determination of six metabolites from multiple cytochrome P450 probe substrates in human liver microsome by liquid chromatography/mass spectrometry: application to high-throughput inhibition screening of ter-penoids..635-643.
- Hickman D, Wang J P, Wang Y, Unadkat JD. (1998). Evaluation of the selectivity ofprobes and suitability of organic solvents for the measurement of human cytochrome P450 monooxygenase activities.207-215.
- Glue P, Clement R P. (1999). Cytochrome P450 enzymes and drug metabolism - Basic concepts and methods of assessment.309-323.
- Jurica J, Kyr M, McCaskey Hadasova E, Tomandl J. (2009). Evaluation of the activity of P450 enzymes in rats: use of the single marker or combined drug administration.(Suppl 1): 92-95.
- Lahoz A, Donato MT, Montero S, Castell JV, Gómez-Lechón MJ. (2008). A newapproach for the simultaneous determination of phase I and phase II enzymatic activities of human hepatocyte preparations. Rapid Commun240-244.
- Otten JN, Hingorani G P, Hartley D P, Kragerud SD, Franklin RB. (2011). An, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.17 - 2 4 .
- Rasmussen MK, Ekstrand B, Zamaratskaia G. (2011). Comparison of cyto-chrome P450 concentrations and metabolic activities in porcine hepatic microsomes prepared with two dif erent methods.343- 346.
- Zamaratskaia G, Zlabek V. (2009). EROD and MROD as markers of cytochrome P450 1A activities in hepatic microsomes from entire and castrated male pigs.2134-2147.
Language: English
Page range: 150 - 154
Published on: Jan 16, 2013
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
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© 2013 Monika Johansson, Jana Tomankova, Shengjie Li, Galia Zamaratskaia, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.