Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Miroslav Pohanka

doi:10.2478/v10102-009-0011-5

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Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Interdisciplinary Toxicology

Volume 2 (2009): Issue 2 (June 2009)

By: Miroslav Pohanka

Open Access

|Jun 2009

Abstract

Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Principle of assay is based on evaluation of cholinesterase activity and its pertinent decrease in presence of analyte. Nerve agents, pesticides, anticholinergic drugs useable for treatment of Alzheimer's disease as well as myasthenia gravis and aflatoxins are enlisted as compounds simply analyzable by cholinesterase biosensors.

References

Arkhypova VN, Dzyadevych SV, Soldatkin AP, Elskaya AV, Jaffrezic-Renault N, Jaffrezic H, Martelet C. (2001). Multibiosensor based on enzyme inhibition analysis for determination of different toxic substances. Talanta 55: 919-927.
Search in Google Scholar
Barthold CL, and Schier JG. (2005). Organic phosphorus compounds - nerve agents. Crit Care Clin 21: 673-689.
Search in Google Scholar
Brecht A, and Gauglitz G. (1995). Optical probes and transducers. Biosens Bioelectron 10: 923-936.
Search in Google Scholar
Buratti FM, D'Aniello A, Volpe MT, Menequz A, and Testai E. (2005). Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms. Drug Metab Dispos 33: 295-302.
Search in Google Scholar
Campanella L, Lelo D, Martini E, and Tomassetti M. (2007). Organophosphorus and carbamete pesticide analysis using an inhibition tyrosinase organic phase enzyme sensor; comparison by butyrylcholinesterase + choline oxidase opee and application to natural waters. Anal Chim Acta 587: 22-32.
Search in Google Scholar
Cometa MF, Lorenzini P, Fortuna S, Volpe MT, Meneguz A, and Palmery M. (2005). In vitro inhibitory effect of aflatoxin B1 on acetylcholinesterase activity in mouse brain. Toxicology 206: 125-135.
Search in Google Scholar
Del Carlo M, Pepe A, Mascini M, De Gregorio M, Visconti A, Compagnone D. (2005). Determinating pirimiphos-methyl in durum wheat samples using an acetylcholinesterase inhibition assay. Anal Bioanal Chem 381: 1367-1372.
Search in Google Scholar
Eddieston M, Buckley NA, Eyer P, and Dawson AH. (2008). Medical management of acute organophosphorus pesticide self-poisoning. Lancet 371: 597-607.
Search in Google Scholar
Egbunike GN, and Ikegwuonu FI. (1984). Effect of aflatoxicosis on acetylcholinesterase activity in the brain and adenohypophysis of the male rat. Neurosci Lett 52: 171-174.
Search in Google Scholar
Ghindilis AL, Atanasov P, Wilkins M, and Wilkins E. (1998). Immunosenors: electrochemical sensing and other engineering approaches. Biosens Bioelectron 13: 113-131.
Search in Google Scholar
Kandimalla, V. B., and Ju, H. (2006). Binding of acetylcholinesterase to multiwall carbon nanotube-cross-linked chitosan composite for flow-injection amperometric detection of an organophosphorous insecticide. Chemistry 12: 1074-1080.
Search in Google Scholar
Lopez S, Bastida J, Viladomat F, and Codina C. (2002). Acetylcholinesterase inhibitory activity of some Amaryllidaceae alkaloids and Narcissus extracts. Life Sci Narcissus 71: 2521-2529.
Search in Google Scholar
Marrs TC. (1993). Organophosphate poisoning. Pharmacol Ther 58: 51-66.
Search in Google Scholar
Musial A, Bajda M, and Malawska B. (2007). Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment. Curr Med Chem 14: 2654-2679.
Search in Google Scholar
Pavlov VA, Wang H, Czura CJ, Friedman SG, and Tracey KJ. (2003). The cholinergic anti-inflammatory pathway: a missing link in neuroimmunomodulation. Mol Med 9: 125 - 134.
Search in Google Scholar
Pijanowska DG, Sprenkels AJ, Olthuis W, and Bergveld P. (2003). A flow-through amperometric sensor for micro-analytical systems. Sens Actuat B 91: 98-102.
Search in Google Scholar
Pohanka M, Jun D, Kalasz H, and Kuca K. (2008b). Cholinesterase biosensor construction - a review. Prot Pept Lett 15: 795-798.10.2174/09298660878520366518855751
Open DOI Search in Google Scholar Open in PubMed
Pohanka M, Kuca K, and Kassa J. (2008a). New performance of biosensor technology for Alzheimer's disease drugs: in vitro comparison of tacrine and 7-methoxytacrine. Neuroendocrinol Lett 29: 755-758.
Search in Google Scholar
Pohanka M, Musilek K, and Kuca K. (2009a). Progress of biosensors based on cholinesterase inhibition. Curr Med Chem 16: 1790-1798.10.2174/09298670978818612919442145
Open DOI Search in Google Scholar Open in PubMed
Pohanka M, Dobes P, Drtinova L, and Kuca K. (2009b). Nerve agents assay using cholinesterase based biosensor. Electroanalysis DOI: 10.1002/elan.200804528.10.1002/elan.200804528
Open DOI Search in Google Scholar
Pohanka M, Jun D, and Kuca K. (2008c). Amperometric biosensor for real time assay of organophosphates. Sensors 8: 5303-5312.10.3390/s8095303370550527873815
Open DOI Search in Google Scholar Open in PubMed
Pohanka M, Kuca K, and Kassa J. (2008d). New performance of biosensor technology for Alzheimer's disease drugs: in vitro comparison of tacrine and 7-methoxytacrine. Neuroendocrinol Lett 29: 755-758.
Search in Google Scholar
Pohanka M, Kuca K, and Jun D. (2008e). Aflatoxin assay using an amperometric sensor strip and acetylcholinesterase as recognition element. Sens Lett 6: 450-453.10.1166/sl.2008.062
Open DOI Search in Google Scholar
Soreq H, and Seidman S. (2001). Acetylcholinesterase - new role for an old actor. Natur Rev 2: 294 - 302.
Search in Google Scholar
Valdes-Ramirez G, Fournier D, Ramirez-Silva MT, and Marty JL. (2008). Sensitive amperometric biosensor for dichlorvos quantification: application to detection of residues on apple skin. Talanta 74: 741-746.
Search in Google Scholar
Yoshinobu T, Schoning MJ, Finger F, Moritz W, and Iwasaki H. (2004). Fabrication of thin film LAPS with amorphous silicon. Sensors 4: 163-169.
Search in Google Scholar

Articles in this issue

DOI: https://doi.org/10.2478/v10102-009-0011-5 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853

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Language: English

Page range: 52 - 54

Published online: Jun 19, 2009

Published in print: Jun 1, 2009

Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine

In partnership with: Paradigm Publishing Services

Keywords:

biosensor,

acetylcholinesterase,

butyrylcholinesterase,

Related subjects:

Pharmacology, toxicology

© 2009 Miroslav Pohanka, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.

Volume 2 (2009): Issue 2 (June 2009)