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Cholinesterase based amperometric biosensors for assay of anticholinergic compounds Cover

Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Open Access
|Jun 2009

Abstract

Biosensors are analytical devices being approachable for multiple analytes assay. Here, biosensors with intercepted acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) are presented as tool for assay of anticholinergic compounds such as pesticides, nerve agents and some natural toxins. Principle of assay is based on evaluation of cholinesterase activity and its pertinent decrease in presence of analyte. Nerve agents, pesticides, anticholinergic drugs useable for treatment of Alzheimer's disease as well as myasthenia gravis and aflatoxins are enlisted as compounds simply analyzable by cholinesterase biosensors.

DOI: https://doi.org/10.2478/v10102-009-0011-5 | Journal eISSN: 1337-9569 | Journal ISSN: 1337-6853
Language: English
Page range: 52 - 54
Published on: Jun 19, 2009
Published by: Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2009 Miroslav Pohanka, published by Slovak Academy of Sciences, Institute of Experimental Pharmacology & Toxicology, Centre of Experimental Medicine
This work is licensed under the Creative Commons License.

Volume 2 (2009): Issue 2 (June 2009)