New steroidal derivatives synthesized using 3β-hydroxyandrosten-17-one as starting material

Nehad Abd El-Latif; Mohamed Abdulla; Abd Amr

doi:10.2478/v10007-007-0044-2

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New steroidal derivatives synthesized using 3β-hydroxyandrosten-17-one as starting material

Acta Pharmaceutica

Volume 58 (2008): Issue 1 (March 2008)

By: Nehad Abd El-Latif, Mohamed Abdulla and Abd Amr

Open Access

|Mar 2008

Abstract

In this study, we synthesized some new substituted steroidal derivatives using 3β-hydroxyandrosten-17-one (dehydroepiandrosterone) as starting material. The synthesized steroidal derivatives 1-11 were evaluated for their androgenic-anabolic activities compared to testosterone as positive control. Details of the synthesis, spectroscopic data and toxicity (LD₅₀) of synthesized compounds are reported.

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Articles in this issue

DOI: https://doi.org/10.2478/v10007-007-0044-2 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075

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Language: English

Page range: 43 - 59

Published on: Mar 12, 2008

Published by: Croatian Pharmaceutical Society

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

dehidroepiandrosteron,

steroidni derivati,

androgeno-anabolički steroidi

Related subjects:

Pharmacy,

Pharmacy, other

© 2008 Nehad Abd El-Latif, Mohamed Abdulla, Abd Amr, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons License.

Volume 58 (2008): Issue 1 (March 2008)