Hypereosinophilia: Clinical Presentations and Diagnostic Distinction between Syndromic and Reactive Entities – A Case Series

Ashaq Hussain Parrey; Basharat Kassana; Hilal Bhat; Mohd. Ismail

doi:10.2478/rjim-2025-0024

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Hypereosinophilia: Clinical Presentations and Diagnostic Distinction between Syndromic and Reactive Entities – A Case Series

Romanian Journal of Internal Medicine

Volume 64 (2026): Issue 1 (March 2026)

By: Ashaq Hussain Parrey, Basharat Kassana, Hilal Bhat and Mohd. Ismail

Open Access

|Dec 2025

Figures & Tables

MRI brain showed multiple bilateral infarcts in supratentorial and bilateral cerebral hemispheres watershed infarcts.

Table 1

Serial blood counts of the patient

Hb	TLC	ANC	ALC	PLT	EOS	AEC
10.4	27.82	8.59	1.95	230	15.89	57.1%
9.4	22.94	6.78	1.88	175	13.16	57.40%
10.2	18.43	16.39	0.94	284	0.03	0.20%
9.20	12.06	10.95	0.57	231	0.03	0.20%

showing fungal hyphae on lymph node biopsy.

Table 2

Serial blood counts of patient with ANCA associated vasculitis

Hb	TLC	ANC	ALC	MCV	MCH	PLT	AEC	Eo %
6.9	13.01	7.29	1.25	88.6	27.2	267	3.59	27.6%
7.6	12.43	8.16	1.43	87	28	278	2.14	17.2%
7.4	11.90	8.21	1.32	89.6	29.6	260	1.76	14.8%
7.6	12.07	8.04	1.58	88.0	28.5	304	1.78	14.7%
6.7	7.48	6.09	0.93	97.8	29.5	343	0.00	0 %

Nerve biopsy showing infiltration of lymphocytes and eosinophils of vessel wall.

Table 3

Serial blood counts of patients with asthma and eosinophilia

Hb	TLC	ANC	ALC	Plt	Eos	AEC
12.7	2O.64	6.6	1.85	269	11.14	54%
12.15	12.2	9.72	2.31	300	1.72	14.2%
12.16	12.0	9.36	1.77	305	0.22	1.9%
12.6	10.0	8.0	1.43	349	0.01	0.1%

References

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Articles in this issue

DOI: https://doi.org/10.2478/rjim-2025-0024 | Journal eISSN: 2501-062X (formerly 1220-4749) | Journal ISSN: 1220-4749

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Language: English, Romanian

Page range: 45 - 51

Submitted on: Oct 6, 2025

Published on: Dec 24, 2025

Published by: N.G. Lupu Internal Medicine Foundation

In partnership with: Paradigm Publishing Services

Keywords:

hypereosinophilia,

hypereosinophilic syndrome,

eosinophilic disorders,

vasculitis,

multisystem involvement,

Related subjects:

Internal medicine, other,

Cardiology,

Gastroenterology,

Rheumatology

© 2025 Ashaq Hussain Parrey, Basharat Kassana, Hilal Bhat, Mohd. Ismail, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 64 (2026): Issue 1 (March 2026)

Hypereosinophilia: Clinical Presentations and Diagnostic Distinction between Syndromic and Reactive Entities – A Case Series

Figures & Tables

Figure 1,2, 3.

Table 1

Figure 4.

Figure 5.

Table 2

Figure 6, 7.

Table 3

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