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The importance of arterial stiffness parameters for predicting Syntax Score in acute coronary syndrome Cover

The importance of arterial stiffness parameters for predicting Syntax Score in acute coronary syndrome

Open Access
|Dec 2025

Figures & Tables

Demographic findings of patients_

NSTEMI (n=53)STEMI (n=51)Total (n=104)p value



Mean±SDMean±SDMean±SD
Age (year)61,94±11,4760,75±13,5161,36±12,460.626
BMI (kg/m2)28,70±5,0428,14±5,4628,43±5,230.578
Gendern (%)n (%)n (%)
  Female23 (43,4)18 (35,3)41 (39,4)0.428
  Male30 (56,6)33 (64,7)63 (60,6)
HT
  no16 (30,2)27 (52,9)43 (41,3)0.028 (2,6 [1,2–5,8])a
  yes37 (69,8)24 (47,1)61 (58,7)
T2DM
  no27 (50,9)35 (68,6)62 (59,6)0.075
  yes26 (49,1)16 (31,4)42 (40,4)
Smoking
  no24 (45,3)21 (41,2)45 (43,2)0.676
  yes29 (54,7)30 (58,8)59 (56,8)

Correlations with PWV

PWVNSTEMISTEMITotal



rPrPrP
Grace Score (mortality),296*0.032,324*0.021,301**0.002
TIMI Score,375**0.006,510**<0,001,456**<0,001
Left atrium diameter (mm)0.2040.142,404**0.003,294**0.002
Age,760**<0,001,861**<0,001,816**<0,001
BMI−0.1110.4270.1930.1750.0570.564
Hb−0.2280.101−0.1540.281−,226*0.021
Total Cholesterol−,363**0.007−0.0890.534−,235*0.016
LDL−0.2030.146−0.090.53−0.1590.106
HDL−0.0060.9650.0210.8840.0040.964
MSBP,317*0.021,361**0.009,332**0.001
MDBP0.0150.9130.0680.6350.0310.757
AIx0.0410.771,422**0.002,247*0.011
LVEF−0.1110.430.1660.2430.0660.507
WBC−,362**0.008−0.0780.588−,211*0.032
RDW0.1640.2420.0780.5880.1230.215
BUN,491**<0,001,563**<0,001,530**<0,001
Creatinine,320*0.02,453**0.001,376**<0,001
Glucose0.1770.205,293*0.037,197*0.045
CK-MB (on admission)−,275*0.0480.2130.133−0.0050.959
Cardiac Index,389**0.004−0.0960.5010.1360.169

Syntax, TIMI, Grace Scores and echocardiographic findings_

NSTEMI (n=53)STEMI (n=51) (%)Total (n=104)P value
Median (Min-Max)Median (Min-Max)Median (Min-Max)
SYNTAX Score14 (2–33)16,5 (3–28,5)15 (2–33)0.943
Grace Score (Mortality)122 (57–222)132 (66–230)128,5 (57–230)0.396
AIx18 (4–61)15 (5–61)17 (4–61)0.359
TIMI Score3 (1–6)3 (1–7)3 (1–7)0.119
LVEF50 (20–65)40 (15–60)46,5 (15–65)0.001
Cardiac Index2,6 (1,4–5,9)2,6 (1,7–4,1)2,6 (1,4–5,9)0.613
Mean±SDMean±SDMean±SD
PWV8,89±1,948,49±2,188,70±2,060.322
Left atrium diameter (mm)37,06±6,3837,06±5,4337,06±5,900.998
Hb12,62±2,3413,71±1,7313,16±2,120.007
MSBP111,49±20,73113,27±19,62112,37±20,110.654
MSDP77,72±13,5081,06±13,9379,36±13,750.230
SYNTAX Scoren (%)n (%)n (%)
  <1118 (34,0)14 (28,0)32 (31,1)0.758
  11–1816 (30,2)18 (36,0)34 (33,0)
  >1819 (35,8)18 (36,0)37 (35,9)

Correlations with Syntax Score

Syntax ScoreNSTEMISTEMITotal



rPrPrP
PWV,356**0.0090.0950.508,237*0.015
Grace (on admission),609**<0,001,325*0.020,484**<0,001
TIMI Score (on admission),609**<0,001,290*0.039,451**<0,001
MSBP−0.1250.3720.0760.594−0.0310.757
MDBP−0.0590.6740.0140.921−0.0170.861
AIx−0.1850.185−0.0390.786−0.1230.214
LVEF−,421**0.002−0.0430.765−,256**0.009
Left atrium diameter (mm)0.2380.086,301*0.032,265**0.006

Laboratory results of patients

Variables (on admission)NSTEMI (n=53)STEMI (n=51)Total (n=104)p value



Mean±SDMean±SDMean±SD
WBC (*103/mm3)11,18±408211,87±411,46±40.238
Hb (g/dL)12,62±2,3413,71±1,7313,16±2,120.007
BUN (mg/dL)51,49±4143,43±3247,7±37,30.183
Creatinin (mg/dL)1,34±0,91,18±0,61,28±0,80.319
Glucose (mg/dL)148,88±84,57154±68,7150,67±76,20.737
Total kolesterol (mg/dL)209,87±58,63216,51±49,63213,13±54,250.545
LDL (mg/dL)124,72±51,71142,39±48,72133,38±50,800.068
HDL (mg/dL)40±10,941±9,641±10,250.736
cTnI (µg/L)3,7±1,142847±16091411±817<0,001
CK-MB (U/L)15,9±44,75899±42002928±21000.046
DOI: https://doi.org/10.2478/rjim-2025-0023 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749
Language: English
Submitted on: Oct 19, 2025
Published on: Dec 18, 2025
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Semih Gülle, Cenk Ekmekci, Harun Akar, Öner Özdoğan, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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