Monosodium urate crystals exposure is associated with limited transcriptional changes in primary human PBMCs
Authors
Valentin Nica
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Medeea Badii
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Department of Internal Medicine and Research Institute for Medical Innovations, Radboud University Medical Center, Nijmegen, the Netherlands
Orsolya Gaal
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Department of Internal Medicine and Research Institute for Medical Innovations, Radboud University Medical Center, Nijmegen, the Netherlands
Georgiana Cabău
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Maartje Cleophas
Department of Internal Medicine and Research Institute for Medical Innovations, Radboud University Medical Center, Nijmegen, the Netherlands
Akshayata Naidu
Department of Computational Biology for Individualised Medicine, Centre for Individualised Infection Medicine (CiiM), TWINCORE, a joint venture between the Helmholtz-Centre for Infection Research (HZI) and Hannover Medical School (MHH), Hannover, Germany, Hannover, Germany
Ioana Hotea
Department of Rheumatology, VieCuri Medical Center, Venlo, Netherlands
Tim L. Jansen
Department of Rheumatology, VieCuri Medical Center, Venlo, Netherlands
Cristina Pamfil
Department of Rheumatology, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Simona Rednic
Department of Rheumatology, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Radu A. Popp
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Yang Li
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Department of Computational Biology for Individualised Medicine, Centre for Individualised Infection Medicine (CiiM), TWINCORE, a joint venture between the Helmholtz-Centre for Infection Research (HZI) and Hannover Medical School (MHH), Hannover, Germany, Hannover, Germany
Tania O. Crișan
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Department of Internal Medicine and Research Institute for Medical Innovations, Radboud University Medical Center, Nijmegen, the Netherlands
Leo A.B. Joosten
Department of Medical Genetics and Department of Translational Immunology, Medfuture Institute for Biomedical Research, UMF “Iuliu Hatieganu”, Cluj-Napoca, Romania
Department of Internal Medicine and Research Institute for Medical Innovations, Radboud University Medical Center, Nijmegen, the Netherlands
Language: English
Page range: 300 - 309
Submitted on: Aug 25, 2025
Published on: Sep 18, 2025
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2025 Valentin Nica, Medeea Badii, Orsolya Gaal, Georgiana Cabău, Maartje Cleophas, Akshayata Naidu, Ioana Hotea, , Tim L. Jansen, Cristina Pamfil, Simona Rednic, Radu A. Popp, Yang Li, Tania O. Crișan, Leo A.B. Joosten, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.