Demographic and clinical characteristics of the patients
| Variables | |
|---|---|
| Female (n, %) | 60 (94.99) |
| Age | 49±7.54 |
| Duration of disease, months, (mean, min–max) | 42.05 (8–141) |
| Digital ulcers (n, %) | 13 (20.63) |
| mRSS (mean, min–max) | 10 (0–25) |
| Diffuse cutaneous SSc (n, %) | 19 (30.23) |
| Limited cutaneous SSc (n, %) | 36 (57.28) |
| Interstitial lung disease (n, %) | 38 (60.32) |
| Pulmonary hypertension (n, %) | 20 (31.75) |
| Fatigue, VAS, (mean±SD) | 5.05±2.52 |
| Pain, VAS, (mean, min–max) | 3.48 (0–8) |
| PGA, VAS, (mean±SD) | 5.04±1.49 |
| HAQ (median, min–max) | 0.44 (0–1) |
Capillaroscopic examination findings of the patients
| Variables | |
|---|---|
| Enlarged capillaries (n, %) | 42 (66.67) |
| Megacapillaries (n, %) | 48 (76.19) |
| Hemorrhages (n, %) | 39 (61.9) |
| Neoangiogenesis (n, %) | 8 (12.7) |
| Loss of capillaries (n, %) | 28 (44.44) |
Comparisons of patients between capillaroscopic pattern groups
| Early Pattern N=21 (A) | Active Pattern N=32 (B) | Late Pattern N=10 (C) | A vs B | p value | |
|---|---|---|---|---|---|
| Female (%) | 19 (90.48) | 31 (96.88) | 10 (100) |
| 0.4250 |
| Age (mean, min–max) | 44 (31–55) | 51 (42–61) | 54 (47–60) |
| <0.0001 |
| Disease duration, months (mean, min–max) | 16.43 (8–21) | 47.59 (22–74) | 78.10 (29–141) |
| <0.0001 |
| Digital ulcers (n, %) | 0 (0) | 5 (15.63) | 8 (80) |
| 0.0006 |
| mRSS (mean, min–max) | 2.36 (0–6) | 10.40 (5–14) | 18.00 (14–25) |
| <0.0001 |
| Diffuse cutaneous SSc (n, %) | 1 (4.76) | 11 (34.38) | 7 (70) |
| <0.0001 |
| Limited cutaneous SSc (n, %) | 13 (61.9) | 18 (56.25) | 5 (50) |
| 0.8160 |
| Interstitial lung disease (n, %) | 8 (38.10) | 21 (65.63) | 9 (90) |
| 0.0161 |
| Pulmonary hypertension (n, %) | 1 (4.76) | 12 (37.5) | 7 (70) |
| 0.0009 |
| Fatigue, VAS (median, min–max) | 4.00 (0–7) | 6.00 (2–9) | 6.50 (3–8) |
| 0.0006 |
| Pain, VAS (mean, min–max) | 5.00 (0–8) | 2.78 (0–6) | 2.50 (0–6) |
| 0.0011 |
| PGA, VAS (mean, min–max) | 4.71 (2.9–6.2) | 5.52 (1.3–7.5) | 4.20 (2.3–7.1) |
| 0.0207 |
| HAQ (mean, min–max) | 0.30 (0–0.7) | 0.48 (0.1–1) | 0.62 (0.1–1) |
| 0.0007 |