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Optical coherence tomography (OCT) vs intravascular ultrasound (IVUS) in diagnosing the mechanisms of in-stent restenosis in drug eluting stents Cover

Optical coherence tomography (OCT) vs intravascular ultrasound (IVUS) in diagnosing the mechanisms of in-stent restenosis in drug eluting stents

Open Access
|Mar 2026

Figures & Tables

Demographic data according to imaging method_

OCT (N = 25)IVUS (N = 25)Stat. testP-value
Age (years)63.8 ± 10.0164.4 ± 12.8T = 0.160.874 NS
SexMale: 14 (56%)Male: 13 (52%)X2 = 0.0810.777 NS
Female: 11 (44%)Female: 12 (48%)

Management according to imaging method_

ManagementOCT (N = 25)IVUS (N = 25)X2P-value
NC5 (20%)2 (8%)1.490.221 NS
DCB13 (52%)9 (36%)1.290.254 NS
DES9 (36%)14 (56%)2.010.156 NS

Time since stent implantation_

OCT (N = 25)IVUS (N = 25)P-value
<1 year560.8
1-3 years13120.85
>3 years770.72

MLA and plaque burden according to imaging method_

OCT (N = 25)IVUS (N = 25)TP-value
MLA2.35 ± 0.852.38 ± 0.770.120.904 NS
Plaque burden78.6 ± 11.677.7 ± 11.40.280.779 NS

Echocardiographic findings according to imaging method_

OCT (N = 25)IVUS (N = 25)TP-value
LVEDD (mm)51.1 ± 6.854.1 ± 6.01.650.105 NS
LVESD (mm)36.4 ± 7.739.7 ± 7.51.520.135 NS
EF (%)54.7 ± 9.850.6 ± 9.51.510.137 NS

Cause of in-stent restenosis according to imaging method_

Cause of Stent FailureOCT (N = 25)IVUS (N = 25)X2P-value
Malapposition12 (48%)4 (16%)5.90.015 S
Under-expansion6 (24%)12 (48%)3.120.077 NS
Edge dissection6 (24%)3 (12%)1.220.269 NS
Neoatherosclerosis13 (52%)5 (20%)5.550.018 S
Neointimal hyperplasia4 (16%)5 (20%)0.130.713 NS

Culprit vessel according to imaging method_

Culprit VesselOCT (N = 25)IVUS (N = 25)X2P-value
LM2 (8%)5 (20%)1.490.221 NS
LAD15 (60%)17 (68%)0.340.556 NS
LCX8 (32%)3 (12%)2.90.088 NS
RCA2 (8%)5 (20%)1.490.221 NS
DOI: https://doi.org/10.2478/rjc-2026-0006 | Journal eISSN: 2734-6382 | Journal ISSN: 1220-658X
Language: English
Published on: Mar 19, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Moustafa Kamal Eldin Ibrahim Khalil Saad, Ahmad Abdelaziz, Fatma Fathelbab, Mahmoud Mohamed Mahmoud Abdallah elmallawany, Khalied Ahmad Emam Elkashab, published by Romanian Society of Cardiology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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