Have a personal or library account? Click to login
A rare cause of mixed hypertrophic and dilated phenotype cardiomyopathy – the MELAS syndrome Cover

A rare cause of mixed hypertrophic and dilated phenotype cardiomyopathy – the MELAS syndrome

Romanian Journal of Cardiology
Volume 33 (2023): Issue 3 (September 2023)
By: Mihnea Casian,  Nic Dragotoiu,  Sebastian Onciul,  Bogdan A. Popescu and  Ruxandra Jurcuţ  
Open Access
|Sep 2023

Figures & Tables

Figure 1

ECG findings showing a short PR interval and the positive delta wave in the lateral leads.
ECG findings showing a short PR interval and the positive delta wave in the lateral leads.

Figure 2

2D Echocardiography findings. A: Parasternal long axis with mild LVH (interventricular septum of 14 mm, posterior wall of 13mm). B: Apical 4 chamber view shows dilatation of all 4 chambers. C: Myocardial deformation bull’s eye showing severely reduced GLS of 05.6% with non-specific pattern.
2D Echocardiography findings. A: Parasternal long axis with mild LVH (interventricular septum of 14 mm, posterior wall of 13mm). B: Apical 4 chamber view shows dilatation of all 4 chambers. C: Myocardial deformation bull’s eye showing severely reduced GLS of 05.6% with non-specific pattern.

Figure 3

Contrast enhanced cardiovascular magnetic resonance findings. A, B, and C: Diastolic frames of cine images in 2, 4 and 3 chamber views showing a severely dilated left ventricle (LV) with interventricular septum hypertrophy. Large right pleural effusion and small circumferential pericardial effusion are also seen. D: Early Gadolinium enhancement showing multiple thrombi in the LV apex. E, F, G, and I: Late Gadolinium Enhancement (LGE) in 2, 4, 3 chambers and short axis views respectively showing extensive subepicardial LGE with a ring-like pattern.
Contrast enhanced cardiovascular magnetic resonance findings. A, B, and C: Diastolic frames of cine images in 2, 4 and 3 chamber views showing a severely dilated left ventricle (LV) with interventricular septum hypertrophy. Large right pleural effusion and small circumferential pericardial effusion are also seen. D: Early Gadolinium enhancement showing multiple thrombi in the LV apex. E, F, G, and I: Late Gadolinium Enhancement (LGE) in 2, 4, 3 chambers and short axis views respectively showing extensive subepicardial LGE with a ring-like pattern.
DOI: https://doi.org/10.2478/rjc-2023-0020 | Journal eISSN: 2734-6382 | Journal ISSN: 1220-658X
Journal RSS Feed
Language: English
Page range: 118 - 122
Published on: Sep 30, 2023
Published by: Romanian Society of Cardiology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
MELAS,
mitochondrial disease,
hereditary cardiomyopathy,
genetic test
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Cardiology,
Pediatrics and juvenile medicine,
Paediatric cardiology,
Surgery,
Cardiac surgery

© 2023 Mihnea Casian, Nic Dragotoiu, Sebastian Onciul, Bogdan A. Popescu, Ruxandra Jurcuţ, published by Romanian Society of Cardiology
This work is licensed under the Creative Commons Attribution 4.0 License.

Previous articleVolume 33 (2023): Issue 3 (September 2023)Next article