Table 1
The groups were comparable in terms of drugs received
| Drugs received | Group 1 n = 116 | Group 2 n = 120 | Group 3 n = 115 | p-value |
|---|---|---|---|---|
| Aspirin | 100% | 100% | 100% | – |
| Clopidogrel | 100% | 100% | 100% | – |
| Heparin and LMWHs | 100% | 100% | 100% | – |
| Statins | 100% | 100% | 100% | – |
| B-blockers | 83.6% | 84.2% | 88.7% | 0.49 |
| ACE inhibitors or ARBs | 83.6% | 88.3% | 91.3% | 0.2 |
| Aldosterone antagonists | 33.6% | 34.2% | 29.6% | 0.72 |
| Calcium antagonist | 22.4% | 20.8% | 13.9% | 0.22 |
| Loop diuretics | 38.8% | 35.8% | 32.2% | 0.58 |
[i] LMWHs, low molecular weight heparins; ACE, angiotensin-converting enzyme; ARBs, angiotensin II receptor blockers
Table 2
Baseline comparability of the study groups
| Variables | Group 1 n = 116 | Group 2 n = 120 | Group 3 n=115 | p-value |
|---|---|---|---|---|
| GFR (ml/min/1.73 m2) | 48.2 ± 10.4 | 74.7 ± 8.7 | 104.1 ±14.6 | < 0.001 |
| Age, years | 66.2±10.1 | 66.2±9.1 | 64.5±6.8 | 0.23 |
| Male | 64.7% | 65% | 75.7% | 0.12 |
| Hypertension | 68.1% | 69.2% | 63.5% | 0.62 |
| Diabetes | 22.4% | 23.3% | 24.3% | 0.94 |
| PMI | 11.2% | 10% | 4.3% | 0.14 |
| Anterior STEMI | 46.6% | 42.5% | 40% | 0.6 |
| Patients with multivessel disease | 46.6% | 52.5% | 41.7% | 0.25 |
| Patients who underwent complete revascularisation | 7.8% | 13.3% | 10.4% | 0.38 |
| Killip > II class at the time of admission | 3.4% | 2.5% | 0.9% | 0.41 |
| LV EF | 39.1±8.5% | 44.5±3.2% | 41.9±6.8% | 0.16 |
| Used contrast volume (ml) | 234.8±65.1 | 231.7±63.7 | 224.5±23 | 0.34 |
[i] GFR, glomerular filtration rate; STEMI, ST-elevation myocardial infarction; PMI, prior myocardial infarction; LV EF left ventricular ejection fraction
Table 3
Effect of glomerular filtration rate on in-hospital complications
| Outcome variable | Group 1 n = 116 | Group 2 n = 120 | Group 3 n = 115 | p Value |
|---|---|---|---|---|
| ALE and CS | 10.3% | 5.8% | 0.9% | < 0.05 |
| Pulseless VT or VF | 2.6% | 3.3% | 0.9% | > 0.05 |
| AF or AFL | 12.1% | 5.8% | 3.5% | < 0.05 |
| In-hospital pneumonia | 13.8% | 6.7% | 4.3% | < 0.05 |
| In-hospital death | 3.4% | 0.8% | 0 | >0.05 |
| CIN needing dialysis | 1.7% | 0 | 0 | > 0.05 |
[i] ALE, acute lung oedema; CS, cardiogenic shock; VT, ventricular tachycardia; VF, ventricular fibrillation; AF, atrial fibrillation; AFL, atrial flutter; CIN contrast-induced nephropathy