Comparative assessment of hydration status in intestinal failure patients receiving home parenteral nutrition using different bioimpedance analysis devices

Taja Jordan; Jernej Ogrin; Nada Rotovnik Kozjek

doi:10.2478/raon-2026-0048

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Comparative assessment of hydration status in intestinal failure patients receiving home parenteral nutrition using different bioimpedance analysis devices

Radiology and Oncology

AHEAD OF PRINT

By: Taja Jordan, Jernej Ogrin and Nada Rotovnik Kozjek

Open Access

|Sep 2026

Abstract

Background

Intestinal failure patients receiving home parenteral nutrition (HPN) are at high risk of dehydration and malnutrition. To optimize clinical care, accurate monitoring tools are required. This study aimed to compare the accuracy of two bioelectrical impedance analysis (BIA) devices, one that offers only BIA results and the other that offers BIA results of bioelectrical impedance vector analysis (BIVA) and bioelectrical impedance spectroscopy (BIS), in assessing hydration and nutritional status in HPN patients.

Patients and methods

In a cross-sectional study, 55 adult HPN patients (33 males, 22 females; mean age 61.5 ±13.1 years) underwent BIA measurements using both devices during routine visits. Parameters measured included total body water (TBW), intracellular and extracellular water, fat-free mass, fat mass, and phase angle. Serum urea and creatinine served as hydration markers. Paired t-tests, Mann-Whitney U tests, and Spearman correlations were used for analysis.

Results

The BIA/BIVA/BIS analysis indicated dehydration in 69.1% of patients compared to 29.1% by BIA (p < 0.001) and showed stronger correlations with serum urea. It also classified more patients as malnourished (24.4% vs. 16.4%, p = 0.436). Correlation between hydration status and phase angle was more pronounced when using phase angle determined with BIA/BIVA/BIS.

Conclusions

BIA/BIVA/BIS measurements in the study demonstrated superior sensitivity in detecting dehydration and assessing nutritional status in HPN patients in comparison to BIA, supporting its use for improved clinical monitoring and management in this group of patients.

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Articles in this issue

DOI: https://doi.org/10.2478/raon-2026-0048 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099

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Language: English

Submitted on: Mar 19, 2026

Accepted on: May 6, 2026

Published on: Sep 7, 2026

Published by: Association of Radiology and Oncology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

intestinal failure,

home parenteral nutrition,

bioelectrical impedance analysis,

bioelectrical impedance vector analysis,

bioelectrical impedance spectroscopy,

Related subjects:

© 2026 Taja Jordan, Jernej Ogrin, Nada Rotovnik Kozjek, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.

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