Predictive value of elastography (Shear-Wave and Elasticity Index) in differentiating benign from malignant breast lesions: a retrospective study in Peru
References
- Arnold M, Morgan E, Rumgay H, Mafra A, Singh D, Laversanne M, et al. Current and future burden of breast cancer: Global statistics for 2020 and 2040. Breast 2022; 66: 15-23. doi: 10.1016/j.breast.2022.08.010
- International Agency for Research on Cancer. Breast cancer cases and deaths are projected to rise globally. Lyon: IARC; 2025 Feb 24. Press Release No. 361
- Terrel-Poccomo MK, Santillán-Romero G, Quispe-Vicuña C, Ybaseta-Medina J, Torres-Roman JS. Trends in breast cancer mortality in Peru and its geographical areas from 2013 to 2022 and prediction until 2027. BMC Cancer 2025; 25: 463. doi: 10.1186/s12885-025-13872-z
- Global Cancer Observatory [Internet]. [cited 2026 Feb 8]. Available at: https://gco.iarc.fr/en?utm_source=chatgpt.com
- Farrell K, Bennett DL, Schwartz TL. Screening for breast cancer: what you need to know. Mo Med 2020; 117: 133-5. PMID: 32308238
- Jacobsen KK, O’Meara ES, Key D, S.m. Buist D, Kerlikowske K, Vejborg I, et al. Comparing sensitivity and specificity of screening mammography in the United States and Denmark. Int J Cancer 2015; 137: 2198-207. doi: 10.1002/ijc.29593
- Kwon MR, Chang Y, Ham SY, Cho Y, Kim EY, Kang J, et al. Screening mammography performance according to breast density: a comparison between radiologists versus standalone intelligence detection. Breast Cancer Res 2025; 26: 1-12. doi: 10.1186/s13058-024-01821-w
- Brem RF, Lenihan MJ, Lieberman J, Torrente J, Brem RF, Lenihan MJ, et al. Screening breast ultrasound:past, present, and future. AJR Am J Roentgenol 2015; 204: 234-40. doi: 10.2214/AJR.13.12072
- Youk JH, Gweon HM, Son EJ. Shear-wave elastography in breast ultrasonography: the state of the art. Ultrasonography 2017; 36: 300-9. doi: 10.14366/usg.17024
- Wang X, He Y, Wang L. Diagnostic value of shear wave elastography combined with super microvascular imaging for BI-RADS 3-5 nodules. Front Oncol 2023; 13: 1192630. doi: 10.3389/fonc.2023.1192630
- Chen YL, Gao Y, Chang C, Wang F, Zeng W, Chen JJ. Ultrasound shear wave elastography of breast lesions: correlation of anisotropy with clinical and histopathological findings. Cancer Imaging 2018; 18: 11. doi: 10.1186/s40644-018-0144-x
- Shi J, Li J, Gao Y, Chen W, Zhao L, Li N, et al. The screening value of mammography for breast cancer: an overview of 28 systematic reviews with evidence mapping. J Cancer Res Clin Oncol 2025: 151: 1-20. doi: 10.1007/s00432-025-06122-z
- Mahmoud ZMS, El-Shinnawy MAM, Ali NSAA. Diagnostic role of shear wave elastography in differentiating benign from malignant breast masses. Egypt J Radiol Nucl Med 2025; 56: 1-9. doi: 10.1186/s43055-025-015484
- Kwon MR, Youn I, Ko ES, Choi SH. Correlation of shear-wave elastography stiffness and apparent diffusion coefficient values with tumor characteristics in breast cancer. Sci Rep 2024; 14: 7180. doi: 10.1038/s41598-024-57832-2
- Marukatat N, Parklug P, Issaragrisil S, Sumanasrethakul C. Shear wave elastography for solid breast masses evaluation: quantitative measurement of mean elasticity value and elasticity ratio. Eur J Radiol 2024; 12: 100573. doi: 10.1016/j.ejro.2024.100573
- Xu J, Zhang L, Wen W, He Y, Wei T, Zheng Y, et al. Evaluation of standard breast ultrasonography by adding two-dimensional and three-dimensional shear wave elastography: a prospective, multicenter trial. Eur Radiol 2023; 34: 945-56. doi: 10.1007/s00330-023-10057-9
- Yan J, Fang S. Diagnostic performance of ultrasound elastography in differentiating malignant from benign breast microcalcifications: a case-control study. BMC Med Imaging 2025; 25: 134. doi: 10.1186/s12880-025-01638-9
- Tang L, Wang Y, Chen P, Chen M, Jiang L. Clinical use and adjustment of ultrasound elastography for breast lesions followed WFUMB guidelines and recommendations in the real world. Front Oncol 2022; 12: 1022917. doi: 10.3389/fonc.2022.1022917
- Cruz-Ramos JA, Trapero-Corona MI, Valencia-Hernández IA, Gómez-Vargas LA, Toranzo-Delgado MT, Cano-Magaña KR, et al. Strain elastography fat-to-lesion index is associated with mammography BI-RADS grading, biopsy, and molecular phenotype in breast cancer. Biosensors 2024; 14: 94. doi: 10.3390/bios14020094
- Urban LABD, Chala LF, Paula IB de, Bauab SDP, Schaefer MB, Oliveira ALK, et al. Recommendations for breast cancer screening in Brazil, from the Brazilian College of Radiology and Diagnostic Imaging, the Brazilian Society of Mastology, and the Brazilian Federation of Gynecology and Obstetrics Associations. Radiol Bras 2023; 56: 207-14. doi: 10.1590/0100-3984.2023.0064-en
- Carcausto Bernal B, Diaz Lazo H. [Diagnostic accuracy of elastography in the evaluation of breast nodules. Spanish]. Rev Per Radiol 2020; 20: 3-11.
- Huang Y, Li F, Han J, Peng C, Li Q, Cao L, et al. Shear wave elastography of breast lesions: Quantitative analysis of elastic heterogeneity improves diagnostic performance. Ultrasound Med Biol 2019; 45: 1909-17. doi: 10.1016/j.ultrasmedbio.2019.04.019
- Lin X, Chang C, Wu C, Chen Q, Peng Y, Luo B, et al. Confirmed value of shear wave elastography for ultrasound characterization of breast masses using a conservative approach in Chinese women: a large-size prospective multicenter trial. Cancer Manag Res 2018; 10: 4447-58. doi: 10.2147/CMAR.S174690
- Guzmán-Aroca F, Martínez-Paredes Y, Berná-Serna JDD, García-Ortega AA, Berná-Mestre JDD, Alcaraz M. Usefulness of elastography for the evaluation of subcentimeter solid breast nodules. Applied Sciences 2021; 11: 1409. doi: 10.3390/app11041409
- Arroyo J, Saavedra AC, Guerrero J, Montenegro P, Aguilar J, Pinto JA, et al. Breast elastography: identification of benign and malignant cancer based on absolute elastic modulus measurement using vibro-elastography [Internet]. SPIE 2018; 105771E. doi: 10.1117/12.2293664. Available at: https://doi.org/10.1117/12.2293664
- Pillai A, Voruganti T, Barr R, Langdon J. Diagnostic accuracy of shear-wave elastography for breast lesion characterization in women: a systematic review and meta-analysis. J Am Coll Radiol 2022; 19: 625-34.e0. doi: 10.1016/j.jacr.2022.02.022
Language: English
Page range: 204 - 216
Submitted on: Dec 17, 2025
Accepted on: Feb 4, 2026
Published on: Apr 16, 2026
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Keywords:
Related subjects:
© 2026 Gaston (Wilmer) Mendoza, Nancy Muñoz, Jorge Aguilar, Jorge Ayón, Diana Díaz-Llontop, Samantha Mendoza, Claudia Quiñones, Richard Castillo, Luis Taxa, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.