References
- O’Sullivan B, Davis AM, Turcotte R, Bell R, Catton C, Chabot P, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet 2002; 359: 2235-41. doi: 10.1016/ S0140-6736(02)09292-9
- Eckert F, Braun LH, Traub F, Kopp HG, Sipos B, Lamprecht U, et al. Radiotherapy and hyperthermia with curative intent in recurrent high risk soft tissue sarcomas. Int J Hyperthermia 2018; 34: 980-7. doi: 10.1080/02656736.2017.1369174
- Eckert F, Gani C, Kluba T, Mayer F, Kopp HG, Zips D, et al. Effect of concurrent chemotherapy and hyperthermia on outcome of preoperative radiotherapy of high-risk soft tissue sarcomas. Strahlenther Onkol 2013; 189: 482-5. doi: 10.1007/s00066-013-0312-7
- Le Cesne A, Ouali M, Leahy MG, Santoro A, Hoekstra HJ, Hohenberger P, et al. Doxorubicin-based adjuvant chemotherapy in soft tissue sarcoma: pooled analysis of two STBSG-EORTC phase III clinical trials. Ann Oncol 2014; 25: 2425-32. doi: 10.1093/annonc/mdu460
- Crompton JG, Ogura K, Bernthal NM, Kawai A, Eilber FC. Local control of soft tissue and bone sarcomas. J Clin Oncol 2018; 36: 111-7. doi: 10.1200/ JCO.2017.75.2717
- Pervaiz N, Colterjohn N, Farrokhyar F, Tozer R, Figueredo A, Ghert M. A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma. Cancer 2008; 113: 573-81. doi: 10.1002/cncr.23592
- Greto D, Saieva C, Loi M, Desideri I, Delli Paoli C, Lo Russo M, et al. Patterns of care and survival in eederly patients with locally advanced soft tissue sarcoma. Am J Clin Oncol 2019; 42: 749-54. doi: 10.1097/ COC.0000000000000594
- Jones RL. Sarcomas and old age: few options for such a large patient population. Future Oncol 2019; 15: 11-5. doi: 10.2217/fon-2019-0489
- Pfeffer MR, Blumenfeld P. The changing paradigm of radiotherapy in the elderly population. Cancer J 2017; 23: 223-30. doi: 10.1097/ PPO.0000000000000271
- Haas RL, Miah AB, LePechoux C, DeLaney TF, Baldini EH, Alektiar K, et al. Preoperative radiotherapy for extremity soft tissue sarcoma; past, present and future perspectives on dose fractionation regimens and combined modality strategies. Radiother Oncol 2016; 119: 14-21. doi: 10.1016/j. radonc.2015.12.002
- Siegel R, Burock S, Wernecke KD, Kretzschmar A, Dietel M, Loy V, et al. Preoperative short-course radiotherapy versus combined radiochemotherapy in locally advanced rectal cancer: a multi-centre prospectively randomised study of the Berlin Cancer Society. BMC Cancer 2009; 9: 50. doi: 10.1186/1471-2407-9-50
- Kosela-Paterczyk H, Szacht M, Morysinski T, Lugowska I, Dziewirski W, Falkowski S, et al. Preoperative hypofractionated radiotherapy in the treatment of localized soft tissue sarcomas. Eur J Surg Oncol 2014; 40: 1641-7. doi: 10.1016/j.ejso.2014.05.016
- Kosela-Paterczyk H, Szumera-Cieckiewicz A, Szacht M, Haas R, Morysinski T, Dziewirski W, et al. Efficacy of neoadjuvant hypofractionated radiotherapy in patients with locally advanced myxoid liposarcoma. Eur J Surg Oncol 2016; 42: 891-8. doi: 10.1016/j.ejso.2016.02.258
- Spencer RM, Aguiar Junior S, Ferreira FO, Stevanato Filho PR, Kupper BE, Silva ML, et al. Neoadjuvant hypofractionated radiotherapy and chemotherapy in high-grade extremity soft tissue sarcomas: Phase 2 Clinical Trial Protocol. JMIR Res Protoc 2017; 6: e97. doi: 10.2196/resprot.6806
- Emami B. Tolerance of normal tissue to therapeutic radiation. Reports Radiother Oncol 2013; 1: 35-48. doi: 10.1016/0360-3016(91)90171-y
- Wang D, Bosch W, Roberge D, Finkelstein SE, Petersen I, Haddock M, et al. RTOG sarcoma radiation oncologists reach consensus on gross tumor volume and clinical target volume on computed tomographic images for preoperative radiotherapy of primary soft tissue sarcoma of extremity in Radiation Therapy Oncology Group studies. Int J Radiat Oncol Biol Phys 2011; 81: e525-8. doi: 10.1016/j.ijrobp.2011.04.038
- Overgaard M. Spontaneous radiation-induced rib fractures in breast cancer patients treated with postmastectomy irradiation. A clinical radio--biological analysis of the influence of fraction size and dose-response relationships on late bone damage. Acta Oncol 1988; 27: 117-22. doi: 10.3109/02841868809090331
- Dickie CI, Parent AL, Griffin AM, Fung S, Chung PW, Catton CN, et al. Bone fractures following external beam radiotherapy and limb-preservation surgery for lower extremity soft tissue sarcoma: relationship to irradiated bone length, volume, tumor location and dose. Int J Radiat Oncol Biol Phys 2009; 75: 1119-24. doi: 10.1016/j.ijrobp.2008.12.006
- Garbay D, Maki RG, Blay JY, Isambert N, Piperno Neumann S, Blay C, et al. Advanced soft-tissue sarcoma in elderly patients: patterns of care and survival. Ann Oncol 2013; 24: 1924-30. doi: 10.1093/annonc/mdt059
- Hoefkens F, Dehandschutter C, Somville J, Meijnders P, Van Gestel D. Soft tissue sarcoma of the extremities: pending questions on surgery and radiotherapy. Radiat Oncol 2016; 11: 136. doi: 10.1186/s13014-016-0668-9
- Larrier NA, Czito BG, Kirsch DG. Radiation Therapy for Soft Tissue Sarcoma: Indications and controversies for neoadjuvant therapy, adjuvant therapy, intraoperative radiation therapy, and brachytherapy. Surg Oncol Clin N Am 2016; 25: 841-60. doi: 10.1016/j.soc.2016.05.012
- Callegaro D, Miceli R, Bonvalot S, Ferguson P, Strauss DC, Levy A, et al. Impact of perioperative chemotherapy and radiotherapy in patients with primary extremity soft tissue sarcoma: retrospective analysis across major histological subtypes and major reference centres. Eur J Cancer 2018; 105: 19-27. doi: 10.1016/j.ejca.2018.09.028
- Tsuda Y, Ogura K, Kobayashi E, Hiruma T, Iwata S, Asano N, et al. Impact of geriatric factors on surgical and prognostic outcomes in elderly patients with soft-tissue sarcoma. Jpn J Clin Oncol 2017; 47: 422-9. doi: 10.1093/ jjco/hyx016
- Moore J, Isler M, Barry J, Mottard S. Major wound complication risk factors following soft tissue sarcoma resection. Eur J Surg Oncol 2014; 40: 1671-6. doi: 10.1016/j.ejso.2014.10.045
- Slump J, Bastiaannet E, Halka A, Hoekstra HJ, Ferguson PC, Wunder JS, et al. Risk factors for postoperative wound complications after extremity soft tissue sarcoma resection: A systematic review and meta-analyses. J Plast Reconstr Aesthet Surg 2019; 72: 1449-64. doi: 10.1016/j.bjps.2019.05.041
- Sabolch A, Feng M, Griffith K, Rzasa C, Gadzala L, Feng F, et al. Risk factors for local recurrence and metastasis in soft tissue sarcomas of the extremity. Am J Clin Oncol 2012; 35: 151-7. doi: 10.1097/COC.0b013e318209cd72
- Bentzen SM, Constine LS, Deasy JO, Eisbruch A, Jackson A, Marks LB, et al. Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): an introduction to the scientific issues. Int J Radiat Oncol Biol Phys 2010; 76(3 Suppl): S3-9. doi: 10.1016/j.ijrobp.2009.09.040
- Jaikuna T, Khadsiri P, Chawapun N, Saekho S, Tharavichitkul E. Isobio software: biological dose distribution and biological dose volume histogram from physical dose conversion using linear-quadratic-linear model. J Contemp Brachytherapy 2017; 9: 44-51. doi: 10.5114/jcb.2017.66082