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Correlation (R) between permeabilization and release of damage-associated molecular pattern molecules (DAMPs) after pulse treatment_ Investigated time points for each molecule are present in the bottom row_ Correlation was evaluated with Pearson correlation coefficient and permeabilization was analyzed by propidium iodide (PI) assay 3 minutes after pulse treatment
| R vs permeabilization (PI) | |||||
|---|---|---|---|---|---|
| MTS | -0.680 | ||||
| ATP | 0.704 | 0.728 (L)/0.594 (F) | -0.695 (F) | ||
| DNA | 0.571 | 0.689 | NS | ||
| RNA | 0.584 | 0.696 | NS | ||
| CRT | 0.535 | 0.556 | |||
| uric acid | NS | ||||
| time after points EP | 3 min | 15 min | 30 min | 4 h | 24 h |
Correlation (R) between survival and release of damage-associated molecular pattern molecules (DAMPs) after pulse treatment_ Investigated time points for each molecule are presented in the bottom row_ Correlation was evaluated with Pearson correlation coefficient and survival was analyzed via MTS assay 24 hours after pulse treatment
| R vs. survival (MTS) | |||||
|---|---|---|---|---|---|
| PI | -0.680 | ||||
| ATP | -0.947 (L) | -0.964 (L)/-0.864 (F) | 0.888 (F) | ||
| DNA | -0.935 | -0.919 | -0.928 | ||
| RNA | -0.909 | -0.909 | -0.919 | ||
| CRT | -0.801 | -0.946 | |||
| uric acid | NS | ||||
| time after points EP | 3 min | 15 min | 30 min | 4 h | 24 h |