Figure 1.

Figure 2.

mDemicco score adapted from Demicco et al_ (8)_
| Variables | Cutoff/Category | Score (Points) |
|---|---|---|
| Age (years> | ≥55 | 1 |
| <55 | 0 | |
| Tumour size (cm) | <5.0 | 0 |
| 5.0 to <10.0 | 1 | |
| 10.0 to <15.0 | 2 | |
| ≥15.0 | 3 | |
| Mitotic count (/10 HPFs) | 0 | 0 |
| 1–3 | 1 | |
| ≥4 | 2 | |
| Tumour necrosis | ≥10% (Present) | 1 |
| <10% (Absent) | 0 |
mDemicco score, risk category adapted from Demicco EG et al_ (8)_
| Total mDemicco Score | Risk Category | Estimated Metastatic Risk |
|---|---|---|
| 0–3 | Low Risk | Very Low (≈0%–5% at 10 years) |
| 4–5 | Intermediate Risk | Moderate (≈10%–15% at 10 years) |
| 6–7 | High Risk | Substantial (≥50% at 5 years) |