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Correlation between IL-33 and IL-13 in asthma exacerbation due to viral infection in adult patients: a cross-sectional study Cover

Correlation between IL-33 and IL-13 in asthma exacerbation due to viral infection in adult patients: a cross-sectional study

Open Access
|Jul 2025

Figures & Tables

Figure 1.

Serum level of IL-33 and viral infection. IL, interleukin.
Serum level of IL-33 and viral infection. IL, interleukin.

Figure 2.

Serum level of IL-13 and viral infection. IL, interleukin.
Serum level of IL-13 and viral infection. IL, interleukin.

Figure 3.

(A and B) Association of IL-33 and IL-13 with viral infection. IL, interleukin.
(A and B) Association of IL-33 and IL-13 with viral infection. IL, interleukin.

Association of viral infection with the severity of asthma exacerbation

Severity of asthma exacerbationVirus-positiveVirus-negativeP-value
Mild-moderate7 (46.7%)26 (76.5%)0.053
Severe8 (53.3%)8 (23.5%)

Profile viral infection in asthma exacerbation

Respiratory virusFrequency%
RV1224.6
Coronavirus12.0
Parainfluenza virus 312.0
Coronavirus and RV12.0
Total1530.6
Negative3469.4

Characteristics of the research subject

VariableVirus-positive (n = 15)Virus-negative (n = 34)P-value
Age (years)37.33 ± 15.7645.91 ± 12.480.067
Gender 0.174
  Male213
  Female1322
Smoking 0.145
  Yes19
  No1425
History of allergy 0.652
  Yes1429
  No15
Duration of asthma (years) 0.538
  <2087
  >201420
Asthma control
  Partially controlled51030.6%
  Uncontrolled102469.4%
Comorbidities
  DM71
  Hypertension31
  GERD10
DOI: https://doi.org/10.2478/pneum-2025-0016 | Journal eISSN: 2247-059X | Journal ISSN: 2067-2993
Language: English
Page range: 105 - 111
Published on: Jul 24, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open

© 2025 Daniel Maranatha, Wiwi Pertiwi, published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.