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An atypical case: RT-PCR-negative, sero-positive covid-19 patient Cover

Abstract

The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency of international concern. The first confirmed COVID-19 case in Indonesia was announced on 2 March 2020, and later on, 11,192 confirmed cases were reported as of 3 May. The World Health Organization has stated that performing a real-time reverse transcription–polymerase chain reaction (RT-PCR) specific for SARS-CoV-2 on specimens from the upper and the lower respiratory tracts, especially nasopharyngeal and oropharyngeal swabs, is the standard diagnostic procedure for COVID-19. In Indonesia, we also use other diagnostic tests, such as rapid antibody tests specific for SARS-CoV-2. Herein, we report an atypical case of COVID-19 and describe the diagnostic process, the clinical course, with progression to severe pneumonia on Week 3 of illness and the case management. We also try to highlight the possibility of false-negative RT-PCR tests.

DOI: https://doi.org/10.2478/pneum-2020-0013 | Journal eISSN: 2247-059X | Journal ISSN: 2067-2993
Language: English
Page range: 107 - 114
Published on: Dec 31, 2020
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open

© 2020 William Suriady, Andika Chandra Putra, Wiwien Heru Wiyono, Mohammad Fahmi Alatas, Bettia Bermawi, Ratna Moniqa, Hendra Koncoro, Laurentius Aswin Pramono, Fransiska, Maria Edith Sulistio, Ramzi, Robert Sinto, Rachmat Hamonangan, Adi Surya Komala, C. Krismini Dwi Irianti, J.B. Endrotomo Sumargono, , published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.