Artificial Intelligence in Hyperbaric Medicine: Examples of Applications
Abstract
Artificial Intelligence (AI) and Machine Learning (ML) are revolutionizing modern medicine and hyperbaric oxygen therapy (HBOT) is currently on the threshold of this transformation. This narrative review analyses current AI applications in HBOT, focusing on four key areas: prognostic modelling, safety monitoring, chamber automation, and precision medicine based on omic data.
In predictive modelling, ML algorithms demonstrate high efficacy in forecasting outcomes for sudden sensorineural hearing loss and chronic wound healing. Regarding safety surveillance, the fusion of autonomic signals (e.g., EDA, HRV) represents a breakthrough in the early detection of CNS oxygen toxicity, allowing preventive introduction of air breaks. Advanced control algorithms allow high-precision protocol execution and personalised compression kinetics. Furthermore, integrating transcriptomic and metabolic data paves the way for a deeper understanding of the mechanisms underlying the response to hyperbaric stress.
Despite promising results, most available evidence comes from single-center retrospective studies. Key obstacles include a lack of standardization for oxygen “dose” variables, limited external validation, and regulatory challenges. This paper identifies translational priorities, such as development of multicenter data registries and implementing “human-in-the-loop” clinical decision support systems. Standardization and prospective validation are essential for AI to become a cornerstone of personalized hyperbaric medicine.
© 2026 Justyna Kęczkowska, Małgorzata Płaza, Piotr Siermontowski, Gabriela Henrykowska, published by Polish Hyperbaric Medicine and Technology Society
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