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A review of emerging trends in experimental, simulation, and theoretical methods for dose calculation in radiation processing Cover

A review of emerging trends in experimental, simulation, and theoretical methods for dose calculation in radiation processing

Open Access
|Aug 2025

Figures & Tables

Fig. 1.

Schematic diagram of dose calculation methods.
Schematic diagram of dose calculation methods.

List of articles focusing on the development of the dosimeter

DosimeterBeamShapeDose rangeReaderUncertaintyReference
TLD-doped silica fibersGammaFiber with a cylinder shape with a diameter of 8.5 μm for core and 125 μm for claddingUp to 20 GyHarshaw 3500 TL readerN/A[14, 28]
Radiochromic film containing poly(hexa-2,4-diynylene adipate)Gamma1 cm × 1 cm size sheets; thickness 0.037 ± 0.004 mm0.5–65 kGyUV–Vis’s spectrophotometer (the measurement wavelength is 520 nm)5.5% (2σ)[33]
Inorganic phosphor particles, NaYF4:Yb3+ and Er3+Low-energy (80/140/200 keV) electron beamLiquid spray (1.6 μm thickness)5–30 kGyThe luminescence decay time of the phosphor was recorded via the photocurrent of a silicon photodiode (Osram SFH2200) equipped with a 980 nm band-pass filter (BrightLine 980/10)15% (2σ)[30, 31]
Silica optical fiber scintillatorsElectron beam (1 MeV)Fiber with a cylinder shape with a diameter of 600 μm for core and 630 μm for cladding10–70 kGyHamamatsu C10082Ca spectrometer (luminescence spectra wavelengths from 200 nm to 800 nm)N/A[29]
PVA films with different concentrations of MTB dyeGammaLiquid stored in 3 ml glass ampoules2.5–20 kGy (for film) and 0.1–1.2 kGy (for solution)UV–Vis spectrophotometry (Shimadzu, Japan); the wave-length ranges from 350 nm to 700 nmN/A[32]
High-density polyethylene (A4009)Gamma; electron beam (2.5 MeV)30 mm × 20 mm × 28 μm25–1000 kGyNICOLET Magna IR-750 spectrometerN/A[35]
FructoseGamma0.5 g of clip plastic0.05–30 kGyMiniScope MS5000 EPR spectrometerN/A[34]
High-density polyethyleneGamma; electron beam (2.5 MeV)30 mm × 4 mm × 28 μm5–193 kGy (for gamma); 5–300 kGy (for electron)Bruker ER 200D spectrometerN/A[36]

Studies related to theoretical methods for processing radiation

YearCalculation methodPhysical parameterObjectAuthorReference
2006Multipole momentFluxCo-60 pencilsLoussaief A.[86]
2007Multipole momentDoseCo-60 pencilsLoussaief A.[87]
2016Haar Wavelet Numerical methodFluxCo-60 pencilsBelkadhi K.[89]
2017Haar Wavelet Numerical methodFluxIrradiated products with different densitiesBelkadhi K.[15]
2017Multipole momentFluxCo-60 pencilsRezaeian P.[88]
2020TOPSISDoseIrradiated product (box)Singh M.[90]
2023Voronoi diagramDoseIrradiated product (box)Singh M.[10]

A list of articles focusing on MC simulation studies related to radiation processing facilities and food irradiation modeling

TypeObjectBeamMC codeParametersYearReference
Modeling of radiation processing facilitiesUSA, JS-7500 MDS Nordion (first category, dry storage)Co-60, GammaMCNPXDose profile2021[61]
Tunisia, C-188 MDS Nordion France (second category, dry storage)Co-60, GammaMCNPXIsodose curve2021[54]
Malaysia, Gamma cell (first category, dry storage)Co-60, GammaMCNPXDose profile2021[61]
Food irradiation modelingMelon (USA)Electron beam 1.35 MeV and 10 MeVMCNP-5Dose distribution, depth-dose curve2010[67]
Egg (USA)10 MeV (high-energy) and 1.35 MeV (low-energy) for electron beams, 5 MeV for X-rays, and 1.25 MeV for gamma raysMCNP-5Dose distribution, depth-dose curve2011[71]
Pineapple (USA)2 MeV (low-energy) and 10 MeV (high-energy) for electron beams, 1.25 MeV for gamma rays, and 5 MeV for X-raysMCNP-5Dose distribution, depth-dose curve2013[72]
Mangosteen (USA)Electron beam (high-energy) and 1.35 MeV (low energy); 5 MeV for X-rays; and 1.25 MeV for Co-60 gamma raysMCNP-5Dose distribution, depth-dose curve2014[77]
Mangoes (USA)1.25 MeV from a Co-60 sourceMCNP-5Dose distribution, depth-dose curve2015[73]
Potatoes, onion (India)2 MeV, 5 MeV, and 10 MeV electron beamsMCNPX2.6Dose distribution, depth-dose curve2018[78]
Pine (USA)10 MeV electron beam and 1.25 MeV gamma raysMCNP-5Dose distribution, depth-dose curve2019[74]
Egg (Japan)80-kV electron beamPHITSSurface and inside dose2023[79]
Apple (Iran)Electron beam = 500 keV; X-ray = 200 kVGeant4Dose distribution, depth-dose curve2023[58]

A list of articles focusing on the development of measurement methods

Dosimeter typeKey resultsMethodBeamYearReference
EBT3 Gafchromic filmExtending the sensitivity of the EBT3 film to high doses up to 100 Gy while ensuring low-dose uncertaintyAn optical setup involving a broadband light source, a fiber optic probe working in reflection configuration, and a spectrometer was used to detect changes in the spectral response of several EBT3 films250 kV X-rays and 1 MeV electron beam2020[37]
AlanineDetermine a scaling factor to convert a dose determination using alanine based on Co-60 calibration to give the dose delivered in a high-energy electron beamThis study combines the alanine dose results of experimental and simulation studies≥6 MeV electron beam2020[41]
PMMAIntroducing a new dosimetry method called Z-scan to optimize the PMMA dosimeterThe Z-scan system was used to measure the non-linear optical properties of the PMMA dosimeter. A He-Cd laser beam (442 nm, 150 mW) was used for this systemGamma2021[40]
AlanineA correction factor that can be used for alanine to measure the kilovoltage is X-raysCombined experimental and MC simulation codes for measuring the dose at several X-rays beam quality20–180 keV X-rays2022[38]
AlanineA model to calculate the relative efficiency of alanine pellets in low-energy X-ray beamsA microdosimetric one-hit detector model was used to characterize the detector’s intrinsic efficiency. Geant4-DNA MC simulations estimated microdosimetric distributions, with literature data providing the free model parametersLow (40–170 kV) and medium X-rays (100–300 kV)2022[45]
B3 filmUnderstanding the effect of heating the B3 film dosimeter on performanceDSC was used to analyze the thermal properties of B3 radiochromic dosimetry films. The glass transition temperature (Tg) and decomposition behavior of irradiated and non-irradiated films were studiedLow-energy electron beam (200 kV)2022[42]
Gafchromic MD-V3 and HD-V2 filmsUnderstanding the effect of temperature on dose measurement during irradiationGafchromic MD-V3 and HD-V2 were irradiated at various temperatures, and their optical densityGamma2022[43]

A list of MC modeling for irradiation facilities

Country/irradiator typeYearIrradiator categoriesBeamSoftware MCParametersExperimentsAgreement MC/EXPReference
Iran, IR-136 irradiator2002IV. Wet storageCo-60, GammaMCNPIsodose curve, absorbed dose, and dose ratePMMA, Fricke, ECB, potassium dichromate dosimeter2.0–6.0%[96]
2002IV. Wet storageCo-60, GammaMCNPAbsorbed dosePMMA, Fricke, ECB, potassium dichromate dosimeter2.0–6.0%[97]
Iran, Gamma Cell1993I. Dry storageCo-60, GammaEGS4Dose rate, fluxFricke<5.0%[98]
2017I. Dry storageCo-60, GammaMCNPFlux distributionPMMAGood agreement[88]
USA, JS-7500 MDS Nordion2003IV wet storageCo-60, GammaITS/ACCEPT MC CodeAbsorbed doseFWT-602.0–5.0%[99]
Portugal, UTR GAMA-Pi2000II. Dry storageCo-60, GammaMCNP 4B2Dose rateAmber perspex and cericaceous dosimetersMax. deviation = 1.08%[100]
2000II. Dry storageCo-60, GammaMCNPFlux, Air Kerma RateIon chamberMax. deviation 12%, avg. MC/EXP = 0.968[101]
2007II. Dry storageCo-60, GammaMCNPXDose rateFrickeAvg. MC/EXP = 0.947 and 1.102, respectively[102]
2008II. Dry storageCo-60, GammaMCNPX, PENELOPEIsodose curve and dose rateFrickeDeviation 2.0–3.0%[53]
2010II. Dry storageCo-60, GammaMCNPXDose rate (per second)Ion chamber and PMMA dosimeterGood agreement[103]
Tunisia, C-188 MDS Nord2005II. Dry storageCo-60, GammaGeant4Dose rate and isodose curveRed Perspex, Gamma-chrome PMMAAvg. deviation of 6.0% (>6.0% for 6 data points)[104]
2005II. Dry storageCo-60, GammaGeant4Isodose curve and dose uniformityRed Perspex, Gamma-chrome PMMAAvg. deviation of 5.0%[105]
2007II. Dry storageCo-60, GammaGeant4Dose, dose rate, transit doseRed Perspex, Gamma-chrome PMMAGood agreement[81]
2017II. Dry storageCo-60, GammaGeant4Absorbed dose, dose rate, dose uniformity, and isodose curvePMMA<3.0%[106]
South Korea, C-188 MDS Nord2008II. Dry storageCo-60, GammaMCNPXDose rateIon chamber and MOSFET dosimeterMax. deviation = 3.0%[107]
South Korea, EB Tech2023N/A2.5 MeV electron beamMCNP 6.2Relative doseCTA film dosimeterGood agreement[108]
UK, JS-7500 MDS Nordion2009Wet storageCo-60, GammaEGSnrcDose rateIon chamber and alanineMax. deviation 2.0% (IC) and 4.0% (alanine)[55]
Vietnam/SVST-Co60 B VINAGAMA2010IV. Wet storageCo-60, GammaMCNP-4CAbsorbed dose, dose rate, and dose uniformityECBMax. deviation = 6.0%[50]
Vietnam2021N/AUERL-10-15S2 linear acceleratorMCNP4cRelative depth doseB3 WINdose<6.0%[64]
Syria2013Wet storageCo-60, GammaMCNP-4CDose rateECB4.0–7.0%[109]
Bangladesh2018II. Dry storageCo-60, GammaMCNPX 2.7Absorbed dose and dose rateFricke and cerebralMax. deviation 12%[110]
Brazil, GB-127 MDS Nordion2017II. Dry storageCo-60, GammaMCNPXDose rate and isodose curveFrickeMax. deviation = 8.03%[111]
2017II. Dry storageCo-60, GammaMCNPX 2.6Absorbed dose, dose rate, isodose curveFrickeMax. deviation = 9.0%[112]
2019II. Dry storageCo-60, GammaMCNPX 2.9Absorbed dose, dose rate, isodose curveFrickeMax. deviation 21%[113]
Malaysia, Gamma cell2017I. Dry storageCo-60, GammaMCNPDose rate and spectrumTLD (silica fiber dosimeter)Max. deviation 6.7%[14]
Croatia2019I. Dry storageCo-60, GammaGeant4Dose rate, transit doseIon chamber5.0–8.0% (Avg. 6.0%)[70]
2024I. Dry storageCo-60, GammaPHITSDose rateIon chamber: ECBMax. deviation = 5.0%[8]
Morocco, Co-602020II. Dry storageCo-60, GammaMCNPXDose rate and isodose curveAlanineMax. deviation 7.3%[114]
2020II. Dry storageCo-60, GammaMCNPXDose rate and isodose curveAlanineMax. deviation = 9.0%[115]
2020II. Dry storageCo-60, GammaMCNPXDose rateFrickeMax. deviation = 9.0%[60]
2021II. Dry storageCo-60, GammaMCNPXDose rateAlanineMax. deviation = 9.0%[62]
2023II. Dry storageCo-60, GammaGeant4Transit doseFrickeMax. deviation = 9.0%[82]
France2022N/AX-rayMCNPX 2.7, RayXpertDose rate, isodose curve, dose-uniformity ratio, spectrumAlanine2.4% and 4.1%[46]

A list of MC modeling for another irradiated object

YearObjectSoftware MCParametersExperimentsAgreement MC/EXPReference
2021, 2023EggPHITSDose and dose distributionRCD, FWT60-180, Far West TechnologyGood agreement[79, 116]
2021CablesMCNP 6.2Energy deposition (MeV/g)CTA film dosimeterGood agreement[66]
2024Aluminum, ethafoam, wood, polystyrenePUFFinDepth-dose distributionCTA, B3-layer film; FWT-60, full-lengthGood agreement[57]
DOI: https://doi.org/10.2478/nuka-2025-0007 | Journal eISSN: 1508-5791 | Journal ISSN: 0029-5922
Language: English
Page range: 59 - 77
Submitted on: Mar 10, 2025
Accepted on: May 7, 2025
Published on: Aug 22, 2025
Published by: Institute of Nuclear Chemistry and Technology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Okky A. Firmansyah, Budhy Kurniawan, Bimo Saputro, Marta Walo, Urszula Gryczka, Nunung Nuraeni, published by Institute of Nuclear Chemistry and Technology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.