Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique

Yuan Wang; Miao Zhang; Tong Song; Zhenqi Chang

doi:10.2478/nuka-2021-0007

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Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique

Nukleonika

Volume 66 (2021): Issue 2 (June 2021)

By: Yuan Wang, Miao Zhang, Tong Song and Zhenqi Chang

Open Access

|Jun 2021

Abstract

A new kind of ¹²⁵I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a ¹²⁵I brachytherapy source fabricated by arranging six ¹²⁵I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The influence of the motion and the core size of the ¹²⁵I seeds on the dose distribution was also studied in this work.

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Articles in this issue

DOI: https://doi.org/10.2478/nuka-2021-0007 | Journal eISSN: 1508-5791 | Journal ISSN: 0029-5922

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Language: English

Page range: 55 - 60

Submitted on: Mar 1, 2020

Accepted on: May 7, 2020

Published on: Jun 8, 2021

Published by: Institute of Nuclear Chemistry and Technology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

¹²⁵I seeds,

Brachytherapy source,

Microfluidic,

Monte Carlo calculation,

Core-shell

Related subjects:

Chemistry,

Nuclear chemistry,

Physics,

Astronomy and astrophysics,

Physics, other

© 2021 Yuan Wang, Miao Zhang, Tong Song, Zhenqi Chang, published by Institute of Nuclear Chemistry and Technology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 66 (2021): Issue 2 (June 2021)