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Dental pulp regeneration via dental pulp stem cells conditioned media and curcumin-loaded nanocomposite hydrogel: an in vitro and in vivo study Cover

Dental pulp regeneration via dental pulp stem cells conditioned media and curcumin-loaded nanocomposite hydrogel: an in vitro and in vivo study

Materials Science-Poland
Volume 42 (2024): Issue 2 (June 2024)
By: Bei’er Ma and  Ren Xu  
Open Access
|Aug 2024

Figures & Tables

Fig. 1.

Viability of DPSCs cultured on CALDPSC-CURCNPs and CALDPSC hydrogels under (A) normal and (B) oxidative stress conditions, * shows p-value < 0.05

Fig. 2.

Graphs showing (A) swelling behavior of CALDPSC-CURCNPs and CALDPSC hydrogels, (B) release of curcumin from CALDPSC-CURCNPs hydrogels, and (C) radical scavenging activity of CALDPSC-CURCNPs and CALDPSC hydrogels compared with ascorbic acid. * shows p-value < 0.05

Fig. 3.

Histograms comparing (A) in vitro anti-inflammatory assay with J774A1 cells cultured on different hydrogel systems and (B) ELISA assay results in dental pulp tissues treated with nanocomposite hydrogels in a rat model, * shows p-value < 0.05

Fig. 4.

Representative scanning electron microscopy images of (A) CURCNPs and (B) curcumin-free nanoparticles

Fig. 5.

Representative scanning electron microscopy images of (A) CALDPSC-CURCNPs and (B) CALDPSC hydrogels

Fig. 6.

Representative H&E staining images of dental pulp tissues treated with (A) CALDPSC-CURCNPs, (B) CALDPSC, (C) CALALG-CURCNPs, and (D) control group

Fig. 7.

Representative Masson’s trichrome staining images of dental pulp tissues treated with (A) CALDPSC-CURCNPs, (B) CALDPSC, (C) CALALG-CURCNPs, and (D) control group

Fig. 8.

Histomorphometry analysis results in pulp tissues treated with different hydrogels. * Shows p-value < 0.05
DOI: https://doi.org/10.2478/msp-2024-0018 | Journal eISSN: 2083-134X | Journal ISSN: 2083-1331
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Language: English
Page range: 113 - 124
Submitted on: Apr 23, 2024
|
Accepted on: May 25, 2024
|
Published on: Aug 30, 2024
Published by: Wroclaw University of Science and Technology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
dental pulp repair,
nanocomposite hydrogel,
drug delivery,
tissue engineering
Related subjects:
Materials sciences,
Materials sciences, other,
Nanomaterials,
Functional and smart materials,
Materials characterization and properties

© 2024 Bei’er Ma, Ren Xu, published by Wroclaw University of Science and Technology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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